{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,14]],"date-time":"2025-11-14T21:35:44Z","timestamp":1763156144463},"reference-count":16,"publisher":"Georg Thieme Verlag KG","issue":"01","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Endosc Int Open"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background and study aims\u2002Exposed endoscopic full-thickness resection (EFTR) enables the operator to obtain a sufficient surgical margin. However, insufflation leakage and secure endoscopic full-thickness closure (EFTC) remain problematic. This study aimed to evaluate the safety and feasibility of a new exposed EFTR.<\/jats:p><jats:p>\n          Patients and methods\u2002Exposed EFTR was performed for 2-cm virtual lesions in different locations of the upper stomach in four dogs. EFTR mainly involved half-circumferential EFTR of the endpoint and clip-line traction. Pulley traction was applied with the forward approach for the greater curvature. EFTC involved endoscopic ligation with O-ring closure to diminish insufflation leakage, followed by over-the-scope clip closure.<\/jats:p><jats:p>\n          Results\u2002Complete resection and technical success were achieved in all four cases. One case of intraoperative bleeding was endoscopically managed. No postoperative complications occurred in any cases. The median maximum resected size was 27.5\u200amm. The median procedure time of the total operation, EFTR, and EFTC was 76, 37, and 35.5 minutes, respectively. The 1-month survival rate was 100\u200a%.<\/jats:p><jats:p>\n          Conclusions\u2002This therapeutic strategy may lead to the establishment of exposed EFTR.<\/jats:p>","DOI":"10.1055\/a-1287-7482","type":"journal-article","created":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T23:30:57Z","timestamp":1609543857000},"page":"E51-E57","source":"Crossref","is-referenced-by-count":14,"title":["Traction-assisted endoscopic full-thickness resection followed by O-ring and over-the-scope clip closure in the stomach: an animal experimental study"],"prefix":"10.1055","volume":"09","author":[{"given":"Hideki","family":"Kobara","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Neurology, Kagawa University, Kagawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noriko","family":"Nishiyama","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Neurology, Kagawa University, Kagawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shintaro","family":"Fujihara","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Neurology, Kagawa University, Kagawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoya","family":"Tada","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Neurology, Kagawa University, Kagawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuhiro","family":"Kozuka","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Neurology, Kagawa University, Kagawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takanori","family":"Matsui","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Neurology, Kagawa University, Kagawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tadayuki","family":"Takata","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Neurology, Kagawa University, Kagawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taiga","family":"Chiyo","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Neurology, Kagawa University, Kagawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nobuya","family":"Kobayashi","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Neurology, Kagawa University, Kagawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koji","family":"Fujita","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Neurology, Kagawa University, Kagawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatsuo","family":"Yachida","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Neurology, Kagawa University, Kagawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keiichi","family":"Okano","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery, Kagawa University, Kagawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuyuki","family":"Suzuki","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery, Kagawa University, Kagawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akira","family":"Nishiyama","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, Kagawa University, Kagawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hirohito","family":"Mori","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Neurology, Kagawa University, Kagawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tsutomu","family":"Masaki","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Neurology, Kagawa University, Kagawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2021,1,1]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"2926","DOI":"10.1007\/s00464-011-1644-y","article-title":"Endoscopic full-thickness resection without laparoscopic assistance for gastric submucosal tumors originated from the muscularis propria","volume":"25","author":"P H Zhou","year":"2011","journal-title":"Surg Endosc"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1055\/s-0043-104526","article-title":"Laparoscopic and luminal endoscopic cooperative surgery can be a standard treatment for submucosal tumors of the stomach: a retrospective multicenter study","volume":"49","author":"T Matsuda","year":"2017","journal-title":"Endoscopy"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.gie.2011.08.018","article-title":"Submucosal tunneling endoscopic resection: a new technique for treating upper GI submucosal tumors originating from the muscularis propria layer (with videos)","volume":"75","author":"M D Xu","year":"2012","journal-title":"Gastrointest Endosc"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"3356","DOI":"10.1007\/s00464-015-4076-2","article-title":"Endoscopic full-thickness resection with defect closure using an over-the-scope clip for gastric subepithelial tumors originating from the muscularis propria","volume":"29","author":"J Guo","year":"2015","journal-title":"Surg Endosc"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1016\/j.gie.2017.07.022","article-title":"Endoscopic full-thickness resection using suture loop needle T-tag tissue anchors in the porcine stomach (with video)","volume":"87","author":"A Dobashi","year":"2018","journal-title":"Gastrointest Endosc"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"E471","DOI":"10.1055\/a-0858-2210","article-title":"Feasibility and safety of third-space endoscopic full-thickness resection in ex vivo and in vivo porcine models","volume":"7","author":"O Goto","year":"2019","journal-title":"Endosc Int Open"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1053\/j.gastro.2014.06.030","article-title":"Balloon-armed mechanical counter traction and double-armed bar suturing systems for pure endoscopic full-thickness resection","volume":"147","author":"H Mori","year":"2014","journal-title":"Gastroenterology"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"E1310","DOI":"10.1055\/a-0860-5387","article-title":"Endoscopic full-thickness resection using an endoluminal-suturing device: a proof-of-concept study","volume":"7","author":"V Huberty","year":"2019","journal-title":"Endosc Int Open"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.gie.2008.03.1126","article-title":"A new technique for gastric endoscopic submucosal dissection: peroral traction-assisted endoscopic submucosal dissection","volume":"69","author":"W J Jeon","year":"2009","journal-title":"Gastrointest Endosc"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.gie.2010.08.041","article-title":"Endoscopic submucosal dissection with the pulley method for early-stage gastric cancer (with video)","volume":"73","author":"C H Li","year":"2011","journal-title":"Gastrointest Endosc"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1055\/a-1149-8597","article-title":"Novel endoscopic ligation with O-ring closure involving muscle layer of a gastric artificial defect","author":"N Nishiyama","year":"2020","journal-title":"Endoscopy"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"3864","DOI":"10.1007\/s00464-019-06920-w","article-title":"The efficacy of dental floss and a hemoclip as a traction method for the endoscopic full-thickness resection of submucosal tumors in the gastric fundus","volume":"33","author":"B Li","year":"2019","journal-title":"Surg Endosc"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1111\/jgh.14402","article-title":"Over-the-scope clip system: A review of 1517 cases over 9 years","volume":"34","author":"H Kobara","year":"2019","journal-title":"J Gastroenterol Hepatol"},{"key":"ref14","first-page":"76","article-title":"Endoscopic full-thickness resection for gastrointestinal lesions using the over-the-scope clip system: a case series","volume":"47","author":"M F\u00e4hndrich","year":"2015","journal-title":"Endoscopy"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1186\/s12876-015-0230-5","article-title":"Closure of iatrogenic large mucosal and full-thickness defects of the stomach with endoscopic interrupted sutures in in vivo porcine models: are they durable enough?","volume":"15","author":"M Kobayashi","year":"2015","journal-title":"BMC Gastroenterol"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"1280","DOI":"10.1136\/gutjnl-2016-313677","article-title":"Colonoscopic full-thickness resection using an over-the-scope device: a prospective multicenter study in various indications","volume":"67","author":"A Schmidt","year":"2018","journal-title":"Gut"}],"container-title":["Endoscopy International Open"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-1287-7482.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T23:32:06Z","timestamp":1609543926000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-1287-7482"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":16,"journal-issue":{"issue":"01","published-online":{"date-parts":[[2021,1,1]]},"published-print":{"date-parts":[[2021,1]]}},"URL":"https:\/\/doi.org\/10.1055\/a-1287-7482","relation":{},"ISSN":["2364-3722","2196-9736"],"issn-type":[{"value":"2364-3722","type":"print"},{"value":"2196-9736","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,1]]}}}