{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T15:21:10Z","timestamp":1785252070930,"version":"3.55.0"},"reference-count":33,"publisher":"Georg Thieme Verlag KG","issue":"01","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Endosc Int Open"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background and study aims\u2002The aim of this study was to elucidate the differences in image-enhanced endoscopy (IEE) findings between Helicobacter-pylori-associated and autoimmune gastritis.<\/jats:p><jats:p>\n          Patients and methods\u2002Seven H. pylori-na\u00efve, 21 patients with H. pylori-associated gastritis and seven with autoimmune gastritis were enrolled. Mucosal atrophy in the corpus was evaluated using autofluorescence imaging and classified into small, medium and large. In a 2\u200a\u00d7\u200a2-cm area of the lesser curvature of the lower corpus, micromucosal pattern was evaluated by magnifying narrow band imaging and proportion of foveola (FV)- and groove (GR)-type mucosa was classified into FV\u200a&gt;\u200a80\u200a%, FV 50\u200a% to 80\u200a%, GR 50\u200a% to 80\u00a0%, and GR\u200a&gt;\u200a80\u200a%, then a biopsy specimen was taken.<\/jats:p><jats:p>\n          Results\u2002Fifteen of 21 (71\u200a%) H. pylori-associated gastritis patients exhibited medium-to-large atrophic mucosa at the corpus lesser curvature. All autoimmune gastritis patients had large atrophic mucosa throughout the corpus (P\u200a&lt;\u200a0.001). All H. pylori-na\u00efve patients had the FV\u200a&gt;\u200a80\u200a% micromucosal pattern. Nineteen of 21 (90\u200a%) H. pylori-associated gastritis patients had varying proportions of GR- and FV-type mucosae and five of seven (71\u200a%) autoimmune gastritis patients showed FV\u200a&gt;\u200a80\u200a% mucosa (P\u200a&lt;\u200a0.001). Compared with patients who were H. pylori-na\u00efve, patients with H. pylori-associated and autoimmune gastritis exhibited a higher grade of atrophy (P\u200a&lt;\u200a0.001), but only patients with H. pylori-associated gastritis showed a higher grade of intestinal metaplasia (P\u200a=\u200a0.022). Large mucosal atrophy with FV\u200a&gt;\u200a80\u200a% micromucosal pattern had sensitivity of 71\u200a% (95\u200a% CI: 29\u00a0%\u201396\u200a%) and specificity of 100\u200a% (95\u200a% CI: 88\u200a% to 100\u200a%) for diagnosis of autoimmune gastritis.<\/jats:p><jats:p>\n          Conclusions\u2002IEE findings of the gastric corpus differed between H. pylori-associated and autoimmune gastritis, suggesting different pathogenesis of the two diseases.<\/jats:p>","DOI":"10.1055\/a-1287-9767","type":"journal-article","created":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T23:30:57Z","timestamp":1609543857000},"page":"E22-E30","source":"Crossref","is-referenced-by-count":21,"title":["Differences in image-enhanced endoscopic findings between Helicobacter pylori-associated and autoimmune gastritis"],"prefix":"10.1055","volume":"09","author":[{"given":"Minoru","family":"Kato","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Oncology, Osaka International Cancer Institute, Osaka, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noriya","family":"Uedo","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Oncology, Osaka International Cancer Institute, Osaka, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ervin","family":"Toth","sequence":"additional","affiliation":[{"name":"Department of Endoscopy, Sk\u00e5ne University Hospital, Lund University, Malm\u00f6, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoki","family":"Shichijo","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Oncology, Osaka International Cancer Institute, Osaka, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akira","family":"Maekawa","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Oncology, Osaka International Cancer Institute, Osaka, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Kanesaka","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Oncology, Osaka International Cancer Institute, Osaka, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoji","family":"Takeuchi","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Oncology, Osaka International Cancer Institute, Osaka, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sachiko","family":"Yamamoto","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Oncology, Osaka International Cancer Institute, Osaka, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koji","family":"Higashino","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Oncology, Osaka International Cancer Institute, Osaka, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryu","family":"Ishihara","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Oncology, Osaka International Cancer Institute, Osaka, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Artur","family":"Nemeth","sequence":"additional","affiliation":[{"name":"Department of Endoscopy, Sk\u00e5ne University Hospital, Lund University, Malm\u00f6, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henrik","family":"Thorlacius","sequence":"additional","affiliation":[{"name":"Department of Surgery, Sk\u00e5ne University Hospital, Lund University, Malm\u00f6, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuhiko","family":"Tomita","sequence":"additional","affiliation":[{"name":"Department of Pathology, Osaka International Cancer Institute, Osaka, Japan"},{"name":"Department of Pathology, International University of Health and Welfare, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriele","family":"Wurm Johansson","sequence":"additional","affiliation":[{"name":"Department of Endoscopy, Sk\u00e5ne University Hospital, Lund University, Malm\u00f6, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2021,1,1]]},"reference":[{"key":"ref1","first-page":"1161","article-title":"Classification and grading of gastritis. 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