{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T13:19:36Z","timestamp":1785763176710,"version":"3.56.0"},"reference-count":31,"publisher":"Georg Thieme Verlag KG","issue":"05","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ultraschall Med"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Purpose\u2002To evaluate the relationship between gastrointestinal (GI) symptoms and transvaginal ultrasound (TVUS) findings suggestive of endometriosis.<\/jats:p><jats:p>Materials and Methods\u2002A prospective design. Women referred for a diagnostic ultrasound due to suspicion of endometriosis completed a Rome III and Pelvic Floor Distress Inventory (PFDI-20) questionnaire for clinical, GI symptoms, before undergoing TVUS.\u200aEndometriosis was diagnosed in the presence of endometriomas and\/or deeply infiltrative endometriotic (DIE) lesions. Association between lesion sites and GI symptoms was evaluated by univariate and multivariate analysis.<\/jats:p><jats:p>Results\u2002The study included 241 women who presented with: dysmenorrhea (89.6\u200a%), dyspareunia (76.3\u200a%), chronic pelvic pain (77.2\u200a%), dyschezia (66\u200a%), hematochezia (15.4\u200a%), subfertility (24.5\u200a%). GI symptoms were present in 25.3\u201376.8\u200a% and 5.4\u201355.6\u200a% of Rome III and PFDI-20 questionnaire responses, respectively. TVUS findings were endometriomas (23.2\u200a%), peritoneal adhesions (46.5\u200a%), uterosacral ligament (26.7\u200a%), retrocervical (11.2\u200a%), rectosigmoid (11.2\u200a%), intestinal (4.6\u200a%), and bladder (0.8\u200a%) involvement, and pouch of Douglas (POD) obliteration (15.4\u200a%). There was a high prevalence of peritoneal adhesions, uterosacral ligament involvement, and rectosigmoid and intestinal nodules on TVUS in women with GI symptoms, up to Chi2\u200a=\u200a9.639 (p\u200a=\u200a0.013) on\u00a0univariate and Chi2\u200a=\u200a8.102 (p\u200a=\u200a0.005) on multivariate analysis.<\/jats:p><jats:p>Conclusion\u2002We observed an almost 10-fold increase in DIE lesions in women with GI symptoms. We suggest that the presence of GI symptoms should prompt a referral for endometriosis evaluation and performance of a dedicated TVUS before invasive gastrointestinal procedures.<\/jats:p>","DOI":"10.1055\/a-1300-1887","type":"journal-article","created":{"date-parts":[[2020,12,15]],"date-time":"2020-12-15T00:00:33Z","timestamp":1607990433000},"page":"e81-e89","source":"Crossref","is-referenced-by-count":13,"title":["The Association Between Gastrointestinal Symptoms and\u00a0Transvaginal Ultrasound Findings in Women Referred for\u00a0Endometriosis Evaluation: A Prospective Pilot Study"],"prefix":"10.1055","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4081-0457","authenticated-orcid":false,"given":"Lee","family":"Cohen Ben-Meir","sequence":"additional","affiliation":[{"name":"Endometriosis center of excellence, Sheba Medical Center, Tel Hashomer, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Soriano","sequence":"additional","affiliation":[{"name":"Endometriosis center of excellence, Sheba Medical Center, Tel Hashomer, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michal","family":"Zajicek","sequence":"additional","affiliation":[{"name":"Endometriosis center of excellence, Sheba Medical Center, Tel Hashomer, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vered","family":"Yulzari","sequence":"additional","affiliation":[{"name":"Endometriosis center of excellence, Sheba Medical Center, Tel Hashomer, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jerome","family":"Bouaziz","sequence":"additional","affiliation":[{"name":"Endometriosis center of excellence, Sheba Medical Center, Tel Hashomer, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Beer-Gabel","sequence":"additional","affiliation":[{"name":"Neurogastroenetrology and Pelvic Floor Unit, Sheba Medical Center, Tel Hashomer, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7457-9957","authenticated-orcid":false,"given":"Vered H.","family":"Eisenberg","sequence":"additional","affiliation":[{"name":"Endometriosis center of excellence, Sheba Medical Center, Tel Hashomer, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2020,12,14]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1111\/1471-0528.14711","article-title":"Epidemiology of endometriosis: a large population-based database study from a healthcare provider with 2\u00a0million members","volume":"125","author":"V H Eisenberg","year":"2018","journal-title":"BJOG An Int J Obstet 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