{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,23]],"date-time":"2025-05-23T01:09:40Z","timestamp":1747962580900},"reference-count":39,"publisher":"Georg Thieme Verlag KG","issue":"06","license":[{"start":{"date-parts":[[2021,5,27]],"date-time":"2021-05-27T00:00:00Z","timestamp":1622073600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Endosc Int Open"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background and study aims\u2002In patients with symptomatic dilation of the main pancreatic duct (MPD) for whom endoscopic retrograde cholangiopancreatography (ERCP) is impossible, surgery has long been the only available treatment. EUS-PD is described as a minimally invasive alternative for ductal decompression surgery. We describe the results of our experience with it.<\/jats:p><jats:p>\n          Patients and methods\u2002This was a retrospective single-center study over 9 years. Twenty-seven patients, median age 61.8 years (range 36 to 85) who underwent EUS-PD for symptomatic MPD dilatation were included. The main objective was to evaluate the technical success (placement of a plastic stent between the stomach and the MPD). Secondary objectives were to document clinical success based on pain and quality of life (visual analogic scales and treatments) and complication rates, and to define a standardized management algorithm.<\/jats:p><jats:p>\n          Results\u2002The technical success rate was 92.5\u200a%. The rate of minor adverse events was 21\u200a% (4 cases of non-specific postoperative pain and two cases of delayed benign edematous pancreatitis). The clinical success rate was 88\u200a%, and half of patients in whom the procedure was successful had \"complete regression\" of pain and half \"partial regression.\" Median follow-up was 34.2 months (range 4 to 108). During follow-up, 74\u200a% of patients reported improvement in quality of life and no patients required secondary surgery.<\/jats:p><jats:p>\n          Conclusion\u2002Provided it is performed in an expert center, EUS-PD is a minimally invasive, effective, and safe alternative to pancreatic surgical drainage in patients with symptomatic MPD dilatation with failure or in whom ERCP is impossible.<\/jats:p>","DOI":"10.1055\/a-1302-1484","type":"journal-article","created":{"date-parts":[[2021,5,27]],"date-time":"2021-05-27T23:16:28Z","timestamp":1622157388000},"page":"E934-E942","source":"Crossref","is-referenced-by-count":5,"title":["Safety and efficacy of EUS-guided pancreatic duct drainage in symptomatic main pancreatic duct obstruction: Is there still a place for surgery?"],"prefix":"10.1055","volume":"09","author":[{"given":"Arthur","family":"Falque","sequence":"additional","affiliation":[{"name":"Aix-Marseille Universit\u00e9, AP-HM, H\u00f4pital Nord, Gastroenterologie, Marseille, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed","family":"Gasmi","sequence":"additional","affiliation":[{"name":"Aix-Marseille Universit\u00e9, AP-HM, H\u00f4pital Nord, Gastroenterologie, Marseille, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marc","family":"Barthet","sequence":"additional","affiliation":[{"name":"Aix-Marseille Universit\u00e9, AP-HM, H\u00f4pital Nord, Gastroenterologie, Marseille, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean-Michel","family":"Gonzalez","sequence":"additional","affiliation":[{"name":"Aix-Marseille Universit\u00e9, AP-HM, H\u00f4pital Nord, Gastroenterologie, Marseille, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2021,5,27]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1177\/2050640614548208","article-title":"Epidemiology of chronic pancreatitis: burden of the disease and consequences","volume":"2","author":"P L\u00e9vy","year":"2014","journal-title":"United Eur Gastroenterol J"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1136\/gut.2010.213835","article-title":"Type of pain, pain-associated complications, quality of life, disability and resource utilisation in chronic pancreatitis: a prospective cohort study","volume":"60","author":"D K Mullady","year":"2011","journal-title":"Gut"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.3109\/00365529008997633","article-title":"Pancreatic tissue fluid pressure in chronic pancreatitis relation to pain, morphology, and function","volume":"25","author":"N Ebbeh\u00f8j","year":"1990","journal-title":"Scand J Gastroenterol"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1053\/j.gastro.2011.04.003","article-title":"Pregabalin reduces pain in patients with chronic pancreatitis in a randomized, controlled trial","volume":"141","author":"S S Olesen","year":"2011","journal-title":"Gastroenterology"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1023\/A:1026607703352","article-title":"Effect of tramadol and morphine on pain and gastrointestinal motor function in patients with chronic pancreatitis","volume":"44","author":"C H Wilder-Smith","year":"1999","journal-title":"Dig Dis Sci"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1055\/s-2007-1010649","article-title":"Stenting in severe chronic pancreatitis: results of medium-term follow-up in seventy-six patients","volume":"23","author":"M Cremer","year":"1991","journal-title":"Endoscopy"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"77","DOI":"10.3109\/00365529009093130","article-title":"Non-surgical management of severe chronic pancreatitis","volume":"175","author":"M Cremer","year":"1990","journal-title":"Scand J Gastroenterol Suppl"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/S0016-5107(96)70189-X","article-title":"Endoscopic pancreatic drainage in chronic pancreatitis associated with ductal stones: long-term results","volume":"43","author":"J-M Dumonceau","year":"1996","journal-title":"Gastrointest Endosc"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1016\/j.gie.2008.12.233","article-title":"Single-operator EUS-guided cholangiopancreatography for difficult pancreaticobiliary access (with video)","volume":"70","author":"B C Brauer","year":"2009","journal-title":"Gastrointest Endosc"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1016\/j.giec.2013.06.011","article-title":"Endoscopic ultrasonography-guided drainage of the pancreatic duct","volume":"23","author":"J Widmer","year":"2013","journal-title":"Gastrointest Endosc Clin N Am"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.gie.2006.06.029","article-title":"EUS-guided pancreatogastrostomy and pancreatobulbostomy for the treatment of pain in patients with pancreatic ductal dilatation inaccessible for transpapillary endoscopic therapy","volume":"65","author":"G Tessier","year":"2007","journal-title":"Gastrointest Endosc"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1067\/mge.2002.125547","article-title":"EUS-guided pancreaticogastrostomy","volume":"56","author":"E Fran\u00e7ois","year":"2002","journal-title":"Gastrointest Endosc"},{"key":"ref13","first-page":"180","article-title":"Radiologic pitfalls in endoscopic retrograde pancreatography: pancreas","volume":"1","author":"A S Fink","year":"1986"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1056\/NEJMoa060610","article-title":"Endoscopic versus surgical drainage of the pancreatic duct in chronic pancreatitis","volume":"356","author":"D L Cahen","year":"2007","journal-title":"N Engl J Med"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1016\/S0039-6060(99)70137-6","article-title":"Surgical decompression of ductal obstruction in patients with chronic pancreatitis","volume":"126","author":"C E Lucas","year":"1999","journal-title":"Surgery"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1097\/00000658-199405000-00006","article-title":"Outcome after lateral pancreaticojejunostomy for chronic pancreatitis","volume":"219","author":"D B Adams","year":"1994","journal-title":"Ann Surg"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1097\/00000658-199305010-00005","article-title":"Progressive loss of pancreatic function in chronic pancreatitis is delayed by main pancreatic duct decompression a longitudinal prospective analysis of the modified Puestow procedure","volume":"217","author":"W H Nealon","year":"1993","journal-title":"Ann Surg"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1001\/archsurg.1994.01420280044006","article-title":"Failure of symptomatic relief after pancreaticojejunal decompression for chronic pancreatitis","volume":"129","author":"J S Markowitz","year":"1994","journal-title":"Strategies for salvage. Arch Surg"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"1704","DOI":"10.1007\/s11605-007-0369-7","article-title":"Long-term Anastomotic Complications After Pancreaticoduodenectomy for Benign Diseases","volume":"11","author":"K M Reid-Lombardo","year":"2007","journal-title":"J Gastrointest Surg"},{"key":"ref20","first-page":"2382","article-title":"Pancreatic duct patency after pancreaticogastrostomy: long-term follow-up study","volume":"45","author":"H Amano","year":"1998","journal-title":"Hepatogastroenterology"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1055\/s-2007-966212","article-title":"Transgastric endoscopic ultrasonography-guided biliary drainage: results of a pilot study","volume":"39","author":"E Bories","year":"2007","journal-title":"Endoscopy"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.gie.2013.01.042","article-title":"Prospective evaluation of a treatment algorithm with enhanced guidewire manipulation protocol for EUS-guided biliary drainage after failed ERCP (with video)","volume":"78","author":"D H Park","year":"2013","journal-title":"Gastrointest Endosc"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"1166","DOI":"10.1016\/j.gie.2009.10.048","article-title":"Therapeutic EUS-assisted endoscopic retrograde pancreatography after failed pancreatic duct cannulation at ERCP","volume":"71","author":"O Barkay","year":"2010","journal-title":"Gastrointest Endosc"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1016\/j.gie.2013.05.016","article-title":"EUS-guided pancreatic duct intervention: outcomes of a single tertiary-care referral center experience","volume":"78","author":"L L Fujii","year":"2013","journal-title":"Gastrointest Endosc"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/S0016-5107(03)02300-9","article-title":"EUS-guided rendezvous drainage of obstructed biliary and pancreatic ducts: report of 6 cases","volume":"59","author":"S Mallery","year":"2004","journal-title":"Gastrointest Endosc"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1007\/s00534-006-1139-8","article-title":"Transgastric pancreatography and EUS-guided drainage of the pancreatic duct","volume":"14","author":"U Will","year":"2007","journal-title":"J Hepatobiliary Pancreat Surg"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/j.gie.2006.05.008","article-title":"EUS-guided pancreaticogastrostomy: analysis of its efficacy to drain inaccessible pancreatic ducts","volume":"65","author":"M Kahaleh","year":"2007","journal-title":"Gastrointest Endosc"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.gie.2016.07.030","article-title":"EUS-guided pancreatic drainage for pancreatic strictures after failed ERCP: a multicenter international collaborative study","volume":"85","author":"A Tyberg","year":"2017","journal-title":"Gastrointest Endosc"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1055\/a-0822-0832","article-title":"Endoscopic treatment of chronic pancreatitis: European Society of Gastrointestinal Endoscopy (ESGE) Guideline \u2013 Updated August 2018","volume":"51","author":"J-M Dumonceau","year":"2019","journal-title":"Endoscopy"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/j.ijsu.2018.04.027","article-title":"Endoscopic versus surgical drainage treatment of calcific chronic pancreatitis","volume":"54","author":"L Jiang","year":"2018","journal-title":"Int J Surg"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1055\/s-2002-34256","article-title":"Endoscopic treatment of chronic pancreatitis: a multicenter study of 1000 patients with long-term follow-up","volume":"34","author":"T R\u00f6sch","year":"2002","journal-title":"Endoscopy"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1016\/S1542-3565(04)00544-0","article-title":"Long-term clinical outcome after endoscopic pancreatic ductal drainage for patients with painful chronic pancreatitis","volume":"2","author":"M Delhaye","year":"2004","journal-title":"Clin Gastroenterol Hepatol"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1016\/S0016-5107(95)70049-8","article-title":"Endoscopic stenting for pain relief in chronic pancreatitis: Results of a standardized protocol","volume":"42","author":"T Ponchon","year":"1995","journal-title":"Gastrointest Endosc"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1002\/jhbp.187","article-title":"Endoscopic ultrasound-guided pancreatic duct drainage","volume":"22","author":"L L Fujii-Lau","year":"2015","journal-title":"J Hepatobiliary Pancreat Sci"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.gie.2016.07.031","article-title":"An international multicenter study comparing EUS-guided pancreatic duct drainage with enteroscopy-assisted endoscopic retrograde pancreatography after Whipple surgery","volume":"85","author":"Y I Chen","year":"2017","journal-title":"Gastrointest Endosc"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"E196","DOI":"10.1055\/a-1005-6573","article-title":"Endoscopic ultrasound-guided pancreatic duct intervention and pancreaticogastrostomy using a novel cross-platform technique with small-caliber devices","volume":"8","author":"U Hayat","year":"2020","journal-title":"Endosc Int Open"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1055\/s-2005-921069","article-title":"Multiple stenting of refractory pancreatic duct strictures in severe chronic pancreatitis: long-term results","volume":"38","author":"G Costamagna","year":"2006","journal-title":"Endoscopy"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/j.gie.2015.07.015","article-title":"Feasibility and safety of a fully covered self-expandable metal stent with antimigration properties for EUS-guided pancreatic duct drainage: early and midterm outcomes (with video)","volume":"83","author":"D Oh","year":"2016","journal-title":"Gastrointest Endosc"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"281","DOI":"10.4103\/eus.eus_86_17","article-title":"Endoscopic ultrasound-guided pancreatic duct drainage: Ready for the prime time?","volume":"6","author":"M Giovannini","year":"2017","journal-title":"Endosc Ultrasound"}],"container-title":["Endoscopy International Open"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-1302-1484.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,27]],"date-time":"2021-05-27T23:21:51Z","timestamp":1622157711000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-1302-1484"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5,27]]},"references-count":39,"journal-issue":{"issue":"06","published-online":{"date-parts":[[2021,5,27]]},"published-print":{"date-parts":[[2021,6]]}},"URL":"https:\/\/doi.org\/10.1055\/a-1302-1484","relation":{},"ISSN":["2364-3722","2196-9736"],"issn-type":[{"value":"2364-3722","type":"print"},{"value":"2196-9736","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,5,27]]}}}