{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,24]],"date-time":"2024-08-24T00:09:40Z","timestamp":1724458180321},"reference-count":30,"publisher":"Georg Thieme Verlag KG","issue":"03","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dtsch Med Wochenschr"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:title>Was ist neu?<\/jats:title><jats:p>Steroide sollen bei der Sepsis\/septischen Schock, der Tuberkulose und der Meningtitis weiterhin nur in bestimmten F\u00e4llen zum Einsatz kommen: N\u00e4mlich bei anders nicht stabilisierbarem Kreislaufversagen in der Sepsis, bei tuberkul\u00f6ser Meningitis oder bei eitriger Meningitis durch Pneumokokken.<\/jats:p><jats:p>Der Einsatz von Steroiden bei eher sp\u00e4ter, hyperinflammatorischer Covid-19-Erkrankung kann die Sterblichkeit wesentlich senken, wobei die Effekte vor allem f\u00fcr sauerstoffpflichtige und intubiert beatmete Patienten signifikant sind, w\u00e4hrend Steroide bei Patienten ohne Sauerstoffpflichtigkeit keine signifikant mortalit\u00e4tssenkende Effekte haben. Untersucht sind Dexamethason, Methylprednisolon und Hydrocortison, wobei die Evidenzlage f\u00fcr Dexamethason am besten ist.<\/jats:p><jats:p>Steroide kommen weiterhin beim Immunrekonstitutionssyndrom (IRIS) des erworbenen Immunschw\u00e4chesyndroms (AIDS) durch HIV zum Einsatz.<\/jats:p>","DOI":"10.1055\/a-1302-3530","type":"journal-article","created":{"date-parts":[[2021,1,29]],"date-time":"2021-01-29T23:31:34Z","timestamp":1611963094000},"page":"162-166","source":"Crossref","is-referenced-by-count":1,"title":["Steroide in der Infektionsmedizin"],"prefix":"10.1055","volume":"146","author":[{"given":"Christoph D.","family":"Spinner","sequence":"additional","affiliation":[{"name":"Technische Universit\u00e4t M\u00fcnchen, Fakult\u00e4t f\u00fcr Medizin, Klinikum rechts der Isar, Klinik und Poliklinik f\u00fcr Innere Medizin II, M\u00fcnchen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00fcrgen","family":"Barton","sequence":"additional","affiliation":[{"name":"Klinikum der Ludwig-Maximilians-Universit\u00e4t Klinikum, Medizinische Klinik und Poliklinik V, M\u00fcnchen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"Biever","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinikum Freiburg, Abteilung Infektiologie, Klinik f\u00fcr Innere Medizin II, Freiburg"},{"name":"Universit\u00e4tsklinikum Freiburg, Klinik f\u00fcr Innere Medizin III, und Universit\u00e4ts-Herzzentrum Freiburg \u2013 Bad Krozingen, Klinik f\u00fcr Kardiologie und Angiologie I, Freiburg"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthias","family":"Klein","sequence":"additional","affiliation":[{"name":"Klinikum der Ludwig-Maximilians-Universit\u00e4t Klinikum, Neurologische Klinik und Poliklinik, 81377 M\u00fcnchen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Siegbert","family":"Rieg","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinikum Freiburg, Abteilung Infektiologie, Klinik f\u00fcr Innere Medizin II, Freiburg"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jochen","family":"Schneider","sequence":"additional","affiliation":[{"name":"Technische Universit\u00e4t M\u00fcnchen, Fakult\u00e4t f\u00fcr Medizin, Klinikum rechts der Isar, Klinik und Poliklinik f\u00fcr Innere Medizin II, M\u00fcnchen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan","family":"Thoden","sequence":"additional","affiliation":[{"name":"Gemeinschaftspraxis Drs. 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