{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T12:16:31Z","timestamp":1756383391837},"reference-count":23,"publisher":"Georg Thieme Verlag KG","issue":"01","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tierarztl Prax Ausg G Grosstiere Nutztiere"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Ziel Das vermehrte Auftreten von Ketose in der Transitphase bei Milchk\u00fchen verursacht hohe \u00f6konomische Verluste. Die fr\u00fchzeitige Identifizierung betroffener Tiere bereits im subklinischen Stadium erm\u00f6glicht, die Erkrankungsh\u00e4ufigkeit zu reduzieren und Verluste zu vermeiden. Ziel der Studie war, die Eignung eines mobilen Testger\u00e4ts zur Analyse der Betahydroxybutyrat-Konzentration (BHB-Konzentration) in der praktischen Anwendung zu pr\u00fcfen. Dar\u00fcber hinaus sollten die mit diesem Ger\u00e4t gemessenen BHB-Konzentrationen mit denen verglichen werden, die mit einer Laborreferenzmethode aus dem Blut der V.\u2005jugularis ermittelt wurden.<\/jats:p><jats:p>Material und Methoden Bei 81\u2005Milchk\u00fchen wurde zu 7\u2005Zeitpunkten (14 und 7\u2005Tage a.\u2005p. sowie 7, 14, 21, 28, 42\u2005Tage p.\u2005p.) Blut f\u00fcr die Analyse der BHB-Konzentration entnommen. Zur Messung im Labor mit einer kinetisch-enzymatischen Methode diente Blut aus der V.\u2005jugularis und V.\u2005oder A.\u2005coccygea mediana, zur Messung mit dem Ger\u00e4t WellionVet\u202fBELUA Blut aus der V.\u2005oder A.\u2005coccygea mediana sowie Kapillarblut (gewonnen am \u00dcbergang der Haut zur Schleimhaut an der Vulva).<\/jats:p><jats:p>Ergebnisse Anf\u00e4ngliche Anwendungsfehler bei der Bedienung des Ger\u00e4ts konnten mit Training abgestellt werden. Bei den Analyseergebnissen im Labor lagen die BHB-Konzentrationen aus dem Blut der V.\u2005jugularis um 0,07\u2005mmol\/l niedriger als die in Blut aus der V.\u2005oder A.\u2005coccygea mediana. Die mit dem Testger\u00e4t ermittelten BHB-Konzentrationen in Proben der V.\u2005oder A.\u2005coccygea mediana lagen um 0,13\u2005mmol\/l niedriger und die im Kapillarblut um 0,12\u2005mmol\/l niedriger als die im Labor aus dem Blut der V.\u2005jugularis gemessenen. Die mit dem Testger\u00e4t gemessenen BHB-Konzentrationen differierten zwischen den beiden Entnahmelokalisationen nicht signifikant.<\/jats:p><jats:p>Schlussfolgerung F\u00fcr die Kapillarblutentnahme eignet sich die Lokalisation am \u00dcbergang von Haut zu Schleimhaut an der Vulva. Das Ger\u00e4t WellionVet BELUA liefert sofort Ergebnisse mit guter \u00dcbereinstimmung zwischen den Messwerten in Proben von verschiedenen Blutentnahmeorten wie auch im Vergleich zur Laboranalyse. Das Testsystem ist zur Anwendung in Milchviehbetrieben geeignet. Als Matrix kann sowohl Kapillarblut als auch Blut aus der V.\u2005oder A.\u2005coccygea mediana empfohlen werden.<\/jats:p>","DOI":"10.1055\/a-1320-4203","type":"journal-article","created":{"date-parts":[[2021,2,16]],"date-time":"2021-02-16T14:53:10Z","timestamp":1613487190000},"page":"5-11","source":"Crossref","is-referenced-by-count":5,"title":["\u00dcberpr\u00fcfung eines Schnelltestsystems zur Erfassung der Betahydroxybutyrat-Konzentration im Blut von Milchk\u00fchen"],"prefix":"10.1055","volume":"49","author":[{"given":"Teja","family":"Snedec","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Klauentiere, Veterin\u00e4rmedizinische Fakult\u00e4t, Universit\u00e4t Leipzig"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kirsten","family":"Theinert","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Klauentiere, Veterin\u00e4rmedizinische Fakult\u00e4t, Universit\u00e4t Leipzig"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabian","family":"Pietsch","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Klauentiere, Veterin\u00e4rmedizinische Fakult\u00e4t, Universit\u00e4t Leipzig"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne-Sophie","family":"Leonhardt","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Klauentiere, Veterin\u00e4rmedizinische Fakult\u00e4t, Universit\u00e4t Leipzig"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mari\u00e1n","family":"Kad\u00e1\u0161i","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Wiederk\u00e4uer, Veterin\u00e4rmedizinische und Pharmazeutische Universit\u00e4t Ko\u0161ice"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Klein","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Wiederk\u00e4uer, Veterin\u00e4rmedizinische und Pharmazeutische Universit\u00e4t Ko\u0161ice"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joachim","family":"Spilke","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Agrar- und Ern\u00e4hrungswissenschaften, der Arbeitsgruppe Biometrie und Agrarinformatik, Martin-Luther-Universit\u00e4t Halle-Wittenberg"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erik","family":"Bannert","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Klauentiere, Veterin\u00e4rmedizinische Fakult\u00e4t, Universit\u00e4t Leipzig"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melanie","family":"Sch\u00e4ren","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Klauentiere, Veterin\u00e4rmedizinische Fakult\u00e4t, Universit\u00e4t Leipzig"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabor","family":"K\u00f6ller","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Klauentiere, Veterin\u00e4rmedizinische Fakult\u00e4t, 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