{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T08:32:48Z","timestamp":1740126768368,"version":"3.37.3"},"reference-count":25,"publisher":"Georg Thieme Verlag KG","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Laryngorhinootologie"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>\n          Zielsetzung\u2002Es war das Ziel dieser Untersuchung, Daten zu epithelialen Speicheldr\u00fcsentumoren im Rahmen einer umfassenden monozentrischen und retrospektiven Analyse zu erheben.<\/jats:p><jats:p>\n          Material und Methoden\u2002Analysiert wurden Patienten mit einer epithelialen Speicheldr\u00fcsenneoplasie, welche zwischen 1993 und 2017 entweder die Klinik f\u00fcr Mund-, Kiefer- und Gesichtschirurgie (MKG) des Universit\u00e4tsklinikums Halle (UKH) aufsuchten oder\/und am Institut f\u00fcr Pathologie (IPA) des UKH diese Diagnose erhielten oder\/und deren Diagnose zwischen 2000 und 2017 dem Statistischen Landesamt Sachsen-Anhalt gemeldet wurde. Folgende Parameter wurden erhoben: demografische Daten, Tumorlokalisation, Tumorentit\u00e4t, Klinik, Therapieverfahren und Verlauf. Die Daten wurden in einer Datenbank im Format SPSS 21.5 erfasst und statistisch analysiert.<\/jats:p><jats:p>\n          Ergebnisse\u2002Im Beobachtungszeitraum wurden unter Verwendung der Datenbanken der MKG sowie des IPA des UKH 382 Patienten mit einer epithelialen Speicheldr\u00fcsenneoplasie registriert. Die h\u00e4ufigste Tumorlokalisation entfiel auf die Gl.\u00a0parotis mit 71\u200a% (n\u200a=\u200a271), w\u00e4hrend 15\u200a% der Tumoren in den kleinen Speicheldr\u00fcsen auftraten (n\u200a=\u200a57). Der Anteil benigner Speicheldr\u00fcsentumoren betrug 80\u200a% (n\u200a=\u200a307). Im genannten Zeitraum waren in Sachsen-Anhalt 5586 Patienten mit epithelialen Speicheldr\u00fcsentumoren gemeldet worden.<\/jats:p><jats:p>\n          Schlussfolgerung\u2002Unserer Kenntnis nach ist dies die erste epidemiologische Analyse zur Evaluation von H\u00e4ufigkeit, Dignit\u00e4t und Therapie von epithelialen Speicheldr\u00fcsenneoplasien in Sachsen-Anhalt. Das pleomorphe Adenom mit der Vorzugslokalisation Ohrspeicheldr\u00fcse ist in unserer Analyse die h\u00e4ufigste Entit\u00e4t. Unter den malignen Pathologien dominiert das adenoid-zystische Karzinom, welches in der Regel von den kleinen Speicheldr\u00fcsen seinen Ausgang nimmt.<\/jats:p>","DOI":"10.1055\/a-1337-3126","type":"journal-article","created":{"date-parts":[[2021,1,12]],"date-time":"2021-01-12T03:48:40Z","timestamp":1610423320000},"page":"896-904","source":"Crossref","is-referenced-by-count":1,"title":["Epitheliale Speicheldr\u00fcsentumoren \u2013 monozentrische retrospektive Erhebung f\u00fcr den S\u00fcden Sachsen-Anhalts"],"prefix":"10.1055","volume":"100","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1471-7630","authenticated-orcid":false,"given":"Theresa Marie","family":"Galdirs","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Plastic Surgery, Martin Luther University Halle-Wittenberg, Halle, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthias","family":"Kappler","sequence":"additional","affiliation":[{"name":"Department of 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