{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T12:01:52Z","timestamp":1778846512820,"version":"3.51.4"},"reference-count":38,"publisher":"Georg Thieme Verlag KG","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Laryngorhinootologie"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>\n          Hintergrund\u2002Die konfokale Laser-Endomikroskopie (CLE) bietet mit einer bis zu 1000-fachen Vergr\u00f6\u00dferungsleistung die M\u00f6glichkeit, Interzellularr\u00e4ume in vivo zu erkennen. Die CLE hat sich in verschiedensten Fachbereichen bereits etabliert. Dieser Artikel gibt einen \u00dcberblick \u00fcber die aktuelle Studienlage der CLE in der Diagnostik des Plattenepithelkarzinoms des Kopf-Hals-Bereichs.<\/jats:p><jats:p>\n          Material und Methoden\u2002Systematische Literaturrecherche in folgenden Online-Datenbanken: PubMed, MEDLINE, Thompson Reuters Web of Science, SPIE nach den Suchbegriffen: confocal laser endomicroscopy, CLE, endomicroscopy, head and neck, larynx. Bewertung der wissenschaftlichen Relevanz der Arbeiten nach festgelegten Kriterien.<\/jats:p><jats:p>\n          Ergebnisse\u2002Es wurden Arbeiten in Bezug auf die klinische Anwendung, die klinische Befunderhebung und die computergest\u00fctzte Datenauswertung analysiert.<\/jats:p><jats:p>\n          Schlussfolgerungen\u2002In Zusammenschau der aktuell publizierten Ergebnisse verspricht die CLE ein gro\u00dfes Potenzial, die Diagnostik maligner Schleimhautver\u00e4nderungen im Bereich des oberen Aerodigestivtrakts zu verbessern.<\/jats:p>","DOI":"10.1055\/a-1339-1635","type":"journal-article","created":{"date-parts":[[2021,1,5]],"date-time":"2021-01-05T23:36:01Z","timestamp":1609889761000},"page":"875-881","source":"Crossref","is-referenced-by-count":9,"title":["Konfokale Laser-Endomikroskopie des Kopf-Hals-Plattenepithelkarzinoms: eine systematische 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Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Florian","family":"Stelzle","sequence":"additional","affiliation":[{"name":"Klinik und Poliklinik f\u00fcr Mund-Kiefer-Gesichtschirurgie, Universit\u00e4tsklinikum Erlangen, Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"Maier","sequence":"additional","affiliation":[{"name":"Pattern Recognition Lab, Computer Science, Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Konstantinos","family":"Mantsopoulos","sequence":"additional","affiliation":[{"name":"Hals-Nasen-Ohrenklinik, Kopf- und Hals-Chirurgie, Universit\u00e4tsklinikum Erlangen, Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg, 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