{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T05:53:23Z","timestamp":1776405203602,"version":"3.51.2"},"reference-count":10,"publisher":"Georg Thieme Verlag KG","issue":"03","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pneumologie"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Die S2k-Leitlinie \u201eDiagnostik und Begutachtung asbestbedingter Erkrankungen\u201c wurde im November 2020 aktualisiert. Dieser Beitrag fasst die wichtigsten \u00c4nderungen zusammen. Neu ist der Hinweis auf das Risiko einer potenziell hohen Exposition gegen\u00fcber Asbestfasern bei der Sanierung von asbesthaltigem Putz, Spachtelmassen und Klebern. Biomarker wie Mesothelin und Calretinin sollen aktuell nur im Rahmen der Forschung eingesetzt werden. Die \u201easbestos airways disease\u201c, die nur histologisch diagnostiziert werden kann, wird als fr\u00fche Form der Asbestose in die Leitlinie aufgenommen. Da das UIP-Muster nicht charakteristisch ist f\u00fcr eine Asbestose, k\u00f6nnen computertomografische F\u00e4lle mit UIP-Muster ohne den gleichzeitigen Nachweis von Pleuraplaques alleine nicht sicher einer Asbestose zugeordnet werden. Bez\u00fcglich der Bewertung des funktionellen Schadens wird auf die gro\u00dfe Bedeutung von Flussvolumenkurve, Ganzk\u00f6rperplethysmografie, Diffusionskapazit\u00e4t und Belastungstests hingewiesen. Wenn verf\u00fcgbar, sind die Referenzwerte nach GLI Grundlage der Bewertung. In der Leitlinie finden sich spezifische Hinweise zur Pr\u00e4vention, medizinischen Behandlung und erstmals zum Stellenwert der ambulanten Rehabilitation und Trainingstherapie. Ferner finden sich Hinweise auf die Begutachtung der neue Berufskrankheit Ovarialkarzinom nach beruflicher Asbestexposition.<\/jats:p>","DOI":"10.1055\/a-1350-1078","type":"journal-article","created":{"date-parts":[[2021,3,17]],"date-time":"2021-03-17T00:05:07Z","timestamp":1615939507000},"page":"201-205","source":"Crossref","is-referenced-by-count":9,"title":["Update der AWMF-S2k-Leitlinie \u201eDiagnostik und Begutachtung asbestbedingter Erkrankungen\u201c \u2013 Was gibt es Neues?"],"prefix":"10.1055","volume":"75","author":[{"given":"T.","family":"Kraus","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Arbeits-, Sozial- und Umweltmedizin Uniklinik RWTH Aachen, Aachen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Teschler","sequence":"additional","affiliation":[{"name":"Ruhrlandklinik Universit\u00e4tsmedizin Essen, Ambulantes Lungenzentrum Essen, Essen"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2021,3,16]]},"reference":[{"key":"ref4","doi-asserted-by":"crossref","first-page":"2238","DOI":"10.1158\/1055-9965.EPI-10-0346","article-title":"Serum mesothelin for early detection of asbestos-induced cancer malignant mesothelioma","volume":"19","author":"J Creaney","year":"2010","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"14321","DOI":"10.1038\/s41598-018-32315-3","article-title":"Prediagnostic detection of mesothelioma by circulating calretinin and mesothelin \u2013 a case-control comparison nested into a prospective cohort of asbestos-exposed workers","volume":"8","author":"G Johnen","year":"2018","journal-title":"Sci Rep"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"462","DOI":"10.5858\/134.3.462","article-title":"Pathology of asbestosis \u2013 An update of the diagnostic criteria: Report of the asbestosis committee of the college of american pathologists and pulmonary pathology society","volume":"134","author":"V L Roggli","year":"2010","journal-title":"Arch Pathol Lab Med"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"1602534","DOI":"10.1183\/13993003.02534-2016","article-title":"The asbestos fibre burden in human lungs: new insights into the chrysotile debate","volume":"49","author":"I S Feder","year":"2017","journal-title":"Eur Respir J"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1111\/his.12951","article-title":"Usual interstitial pneumonia in asbestos-exposed cohorts \u2013 concurrent idiopathic pulmonary fibrosis or atypical asbestosis?","volume":"69","author":"R L Attanoos","year":"2016","journal-title":"Histopathology"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1164\/rccm.200310-1436ST","article-title":"Diagnosis and initial management of nonmalignant diseases related to asbestos","volume":"170","author":"American Thoracic Society","year":"2004","journal-title":"Am J Respir Crit Care Med"},{"key":"ref10","first-page":"114","volume-title":"Bildgebende Verfahren bei der Begutachtung respiratorischer Erkrankungen","author":"K G Hering","year":"2009"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"1324","DOI":"10.1183\/09031936.00080312","article-title":"Multi-ethnic reference values for spirometry for the 3-95-yr age range: the global lung function 2012 equations","volume":"40","author":"P H Quanjer","year":"2012","journal-title":"Eur Respir J"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1097\/JOM.0b013e31821aa964","article-title":"Spirometry in the occupational health setting \u2013 2011 update","volume":"53","author":"M C Townsend","year":"2011","journal-title":"J Occup Environ Med"},{"key":"ref13","volume-title":"The Health Effects of Asbestos: An Evidence-based Approch","author":"D D Smith","year":"2016"}],"container-title":["Pneumologie"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-1350-1078.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,3,17]],"date-time":"2021-03-17T00:05:40Z","timestamp":1615939540000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-1350-1078"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3]]},"references-count":10,"journal-issue":{"issue":"03","published-online":{"date-parts":[[2021,3,16]]},"published-print":{"date-parts":[[2021,3]]}},"URL":"https:\/\/doi.org\/10.1055\/a-1350-1078","relation":{},"ISSN":["0934-8387","1438-8790"],"issn-type":[{"value":"0934-8387","type":"print"},{"value":"1438-8790","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,3]]}}}