{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T11:39:18Z","timestamp":1787312358087,"version":"build-2736575974"},"reference-count":18,"publisher":"Georg Thieme Verlag KG","issue":"05","license":[{"start":{"date-parts":[[2021,5,20]],"date-time":"2021-05-20T00:00:00Z","timestamp":1621468800000},"content-version":"vor","delay-in-days":19,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Geburtshilfe Frauenheilkd"],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>In 2017, ovarian cancer due to asbestos exposure was designated a new, and thereby the first, gynaecological occupational disease in Germany. Asbestos is a naturally occurring mineral fibre with an annual usage in Germany of 160\u200a000\u200a\u2013\u200a180\u200a000 metric tonnes in the 1960s and 1970s. The carcinogenicity of asbestos for the target organs lungs, larynx, pleura including pericardium, and peritoneum including tunica vaginalis testis has been clearly established for many years. Recent meta-analyses of data from cohort studies have demonstrated that the risk of ovarian cancer roughly doubles in women with occupational exposure to asbestos. Since the group of people with double the risk of developing lung cancer due to work-related asbestos exposure has a 2.25-fold increased risk of mortality from ovarian cancer on average, work-related ovarian cancer has been assigned the same recognition requirements as in occupational lung (and laryngeal) cancer. Thus, gynaecologists must obtain\n\t\t\t\t\ta thorough history of occupational exposure to asbestos, even if it may have taken place long in the past. The law mandates that suspected such cases must be reported to the Statutory Accident Insurance carrier or the State Occupational Safety and Health Agency.<\/jats:p>","DOI":"10.1055\/a-1361-1715","type":"journal-article","created":{"date-parts":[[2021,5,20]],"date-time":"2021-05-20T18:38:51Z","timestamp":1621535931000},"page":"555-561","source":"Crossref","is-referenced-by-count":15,"title":["Asbestos Exposure and Ovarian Cancer \u2013 a Gynaecological Occupational Disease. Background, Mandatory Notification, Practical Approach"],"prefix":"10.1055","volume":"81","author":[{"given":"Dennis","family":"Nowak","sequence":"additional","affiliation":[{"name":"Institut und Poliklinik f\u00fcr Arbeits-, Sozial- und Umweltmedizin, LMU Klinikum, M\u00fcnchen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Schmalfeldt","sequence":"additional","affiliation":[{"name":"Klinik und Poliklinik f\u00fcr Gyn\u00e4kologie, Universit\u00e4tsklinikum Hamburg-Eppendorf, Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Tannapfel","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Pathologie der Ruhr-Universit\u00e4t Bochum, Berufsgenossenschaftliches Universit\u00e4tsklinikum Bergmannsheil, Bochum, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sven","family":"Mahner","sequence":"additional","affiliation":[{"name":"Klinik und Poliklinik f\u00fcr Frauenheilkunde und Geburtshilfe, LMU Klinikum, M\u00fcnchen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2021,5,20]]},"reference":[{"key":"ref3","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1007\/s12672-010-0054-2","article-title":"Microenvironment and pathogenesis of epithelial ovarian cancer","volume":"1","author":"A F Saad","year":"2010","journal-title":"Horm Cancer"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"1459","DOI":"10.1093\/jnci\/91.17.1459","article-title":"Possible role of ovarian epithelial inflammation in ovarian cancer","volume":"91","author":"R B Ness","year":"1999","journal-title":"J Natl Cancer Inst"},{"key":"ref5","first-page":"239","article-title":"NF-kappaB, macrophage migration inhibitory factor and cyclooxygenase-inhibotions als likely mechanisms behind the acetaminophen- and NSAID-prevention of the ovarian cancer","volume":"51","author":"M A Altinoz","year":"2004","journal-title":"Neoplasma"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1289\/ehp.1003283","article-title":"Occupational exposure to asbestos and ovarian cancer: a meta-analysis","volume":"119","author":"M C Camargo","year":"2011","journal-title":"Environ Health Perspect"},{"key":"ref9","first-page":"261","article-title":"T\u00f6dliche Peritonealmesotheliomerkrankungen bei Frauen infolge Asbesteinwirkung am Arbeitsplatz","volume":"21","author":"K Gro\u00dfgarten","year":"1991","journal-title":"Gyn\u00e4kologe"},{"key":"ref10","first-page":"114","article-title":"Verteilung von Asbestk\u00f6rpern in menschlichen Organen","volume":"10","author":"M Marten","year":"1989","journal-title":"Pathologe"},{"key":"ref11","first-page":"1955","article-title":"Perineal application of cosmetic talc and risk of invasive epithelial ovarian cancer: a meta-analysis of 11,933 subjects from sixteen observational studies","volume":"23","author":"M Huncharek","year":"2003","journal-title":"Anticancer Res"},{"key":"ref12","first-page":"811","article-title":"Genital powder use and risk of ovarian cancer: A pooled analysis of 8525 cases and 9859 controls","volume":"6","author":"K L Terry","year":"2013","journal-title":"Cancer Prev Res"},{"key":"ref13","first-page":"181","article-title":"A meta-analytical approach examining the potential relationship between talc exposure and ovarian cancer","volume":"5","author":"A J Gross","year":"1995","journal-title":"J Expo Anal Environ Epidemiol"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"1411","DOI":"10.1158\/1055-9965.EPI-15-1281","article-title":"Association between body powder use and ovarian cancer: The African American Cancer Epidemiology Study (AACES)","volume":"25","author":"J M Schildkraut","year":"2016","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"1369","DOI":"10.1158\/1055-9965.EPI-16-0476","article-title":"Body powder and ovarian cancer risk \u2013 what is the role of recall bias?","volume":"25","author":"B Trabert","year":"2016","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"ref16","first-page":"142","article-title":"Determinants of inflammatory markers in a bi-ethnic population","volume":"21","author":"M Paalani","year":"2011","journal-title":"Ethn Dis"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1158\/1055-9965.EPI-10-1302","article-title":"Does exposure to asbestos cause ovarian cancer? A systematic literature review and meta-analysis","volume":"20","author":"A Reid","year":"2011","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"ref18","first-page":"1089","article-title":"Professional risk factors associated with the cancer of the ovary. Literature review","volume":"101","author":"A Bounin","year":"2014","journal-title":"Bull Cancer"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"1487","DOI":"10.1055\/a-0754-0498","article-title":"Zusammenhangsbegutachtung von Berufskrankheiten \u2013 die Rolle des Arztes","volume":"144","author":"D Nowak","year":"2019","journal-title":"Dtsch Med Wochenschr"},{"key":"ref20","volume-title":"Verdacht auf Berufskrankheit. Darauf kommt es beim Berufskrankheiten-Verfahren an! 3. Aufl","author":"D Nowak","year":"2018"},{"key":"ref21","volume-title":"Essentials Arbeitsmedizin. Das Wichtigste f\u00fcr \u00c4rzte aller Fachrichtungen","author":"D Nowak","year":"2018"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"1341","DOI":"10.1186\/s12889-019-7590-7","article-title":"Investigating the association between occupational exposure to asbestos and ovarian carcinoma: results from a pilot study in Germany","volume":"19","author":"Z Rajput","year":"2019","journal-title":"BMC Public Health"}],"container-title":["Geburtshilfe und Frauenheilkunde"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-1361-1715.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,20]],"date-time":"2021-05-20T18:40:19Z","timestamp":1621536019000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-1361-1715"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5]]},"references-count":18,"journal-issue":{"issue":"05","published-online":{"date-parts":[[2021,5,20]]},"published-print":{"date-parts":[[2021,5]]}},"URL":"https:\/\/doi.org\/10.1055\/a-1361-1715","relation":{},"ISSN":["0016-5751","1438-8804"],"issn-type":[{"value":"0016-5751","type":"print"},{"value":"1438-8804","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,5]]}}}