{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T08:33:26Z","timestamp":1740126806772,"version":"3.37.3"},"reference-count":62,"publisher":"Georg Thieme Verlag KG","issue":"03","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aktuelle Urol"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Harnr\u00f6hrenstrikturen der Frau sind ein seltenes Krankheitsbild mit individueller Symptomatik. Vor diesem Hintergrund mangelt es an klinischen Leitf\u00e4den, die sich mit Diagnostik und Therapie dieser Erkrankung befassen. Mittlerweile liegen einige Ergebnisse zu verschiedenen Operationstechniken vor, ein direkter inter-institutioneller Vergleich wird jedoch durch heterogene Patientenkohorten und kleine Fallzahlen erschwert. Die vorliegende Arbeit befasst sich mit einer aktuellen narrativen Literatur\u00fcbersicht relevanter Artikel zur klinischen Diagnostik und zu den Therapiem\u00f6glichkeiten bei weiblicher Harnr\u00f6hrenstriktur.<\/jats:p><jats:p>Iatrogene Ursachen wie eine vorangegangene Katheterisierung oder ein urogenitaler operativer Eingriff sind die h\u00e4ufigsten Gr\u00fcnde f\u00fcr die Entstehung einer Harnr\u00f6hrenstriktur bei der Frau. Im klinischen Alltag stellt die k\u00f6rperliche Untersuchung einen wichtigen Grundstein in der Differentialdiagnostik dar, um bei Verdacht auf eine anatomisch-morphologische Ursache der Harnblasenentleerungsst\u00f6rung weitere diagnostische Ma\u00dfnahmen (Urethrozystoskopie, Urethrographie, MRT) einzuleiten. Therapeutisch sind minimal-invasive Eingriffe wie Harnr\u00f6hrenbougierungen oder Urethrotomien oftmals nur mit kurzfristigem Erfolg assoziiert, sodass die offene Harnr\u00f6hrenrekonstruktion mit langfristigeren Therapieerfolgen hier eine Sonderstellung einnimmt. Zur Verf\u00fcgung stehen neben offenen Harnr\u00f6hrenplastiken mit gestielten Lappen aus Vaginal- oder Labialschleimhaut auch die Verwendung freier Transplantate, vor allem dem Mundschleimhaut-Autotransplantat. Aufgrund der genannten Seltenheit der Erkrankung mit nur kleinen publizierten Fallserien ist jedoch eine Beurteilung der vergleichenden Wirksamkeit der verschiedenen Techniken nur schwer m\u00f6glich. Wie bei allen seltenen Erkrankungen bedarf es hier der Etablierung von multizentrischen, gro\u00dfen Serien, um die Standards im perioperativen Vorgehen zu verbessern.<\/jats:p>","DOI":"10.1055\/a-1367-6565","type":"journal-article","created":{"date-parts":[[2021,4,16]],"date-time":"2021-04-16T07:04:38Z","timestamp":1618556678000},"page":"260-267","source":"Crossref","is-referenced-by-count":0,"title":["Harnr\u00f6hrenstrikturen der Frau: Aktuelles zu Diagnostik und Therapie"],"prefix":"10.1055","volume":"52","author":[{"given":"Lennart","family":"K\u00fchnke","sequence":"additional","affiliation":[{"name":"Klinik und Poliklinik f\u00fcr Urologie, Universit\u00e4tsklinikum Hamburg-Eppendorf"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margit","family":"Fisch","sequence":"additional","affiliation":[{"name":"Klinik und Poliklinik f\u00fcr Urologie, Universit\u00e4tsklinikum 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