{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,31]],"date-time":"2022-03-31T20:49:53Z","timestamp":1648759793054},"reference-count":11,"publisher":"Georg Thieme Verlag KG","issue":"04","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Z Gastroenterol"],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A 50-year-old female patient with cirrhosis due to alcoholic steatohepatitis was referred to our department because of recurrent hepatorenal syndrome (HRS) and hepatic hydrothorax. Clinically, severe anasarca was the leading problem. In contrast to previous episodes, HRS did not respond to standard treatment including terlipressin.<\/jats:p><jats:p>Given the severe, refractory hyperhydration, we finally initiated renal replacement therapy (RRT). Subsequently, RRT was performed without severe side effects for more than 100\u00a0days. In the meantime, liver function remarkably improved, most probably due to the prolonged abstinence from alcohol. Finally, RRT could be stopped. Since then, our patient has remained in good clinical condition for more than 6 months, with well-compensated Child-Pugh stage A cirrhosis and only mild chronic kidney disease stage III.<\/jats:p><jats:p>In conclusion, this case highlights that RRT may be considered in individual cases as bridging therapy in refractory HRS until the liver regenerates due to the absence of damaging mechanisms.<\/jats:p>","DOI":"10.1055\/a-1369-9859","type":"journal-article","created":{"date-parts":[[2021,2,26]],"date-time":"2021-02-26T01:09:40Z","timestamp":1614301780000},"page":"331-335","source":"Crossref","is-referenced-by-count":0,"title":["Renal replacement therapy as bridging-to-recovery in refractory hepatorenal syndrome"],"prefix":"10.1055","volume":"59","author":[{"given":"Christoph","family":"Luedemann","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine I, University Hospital Bonn, Venusberg Campus 1, Bonn, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jessica","family":"Plota","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine I, University Hospital Bonn, Venusberg Campus 1, Bonn, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacob","family":"Nattermann","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine I, University Hospital Bonn, Venusberg Campus 1, Bonn, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian P.","family":"Strassburg","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine I, University Hospital Bonn, Venusberg Campus 1, Bonn, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philipp","family":"Lutz","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine I, University Hospital Bonn, Venusberg Campus 1, Bonn, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felix","family":"Goeser","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine I, University Hospital Bonn, Venusberg Campus 1, Bonn, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2021,2,25]]},"reference":[{"key":"ref1","first-page":"1","article-title":"Kidney Disease: Improving Global Outcomes (KDIGO). 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Long-term treatment with terlipressin as a brigde to liver transplantation","volume":"41","author":"N Ganne-Carrie","year":"1996","journal-title":"Dig Dis Sci"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1016\/j.jhep.2018.03.024","article-title":"EASL Clinical Practice Guidelines for the management of patients with decompensated cirrhosis","volume":"69","author":"The European Association for the Study of the Liver","year":"2018","journal-title":"J Hepatol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1002\/hep.23383","article-title":"The role of transjugular intrahepatic portosystemic shunt (tips) in the management of portal hypertension: Update 2009","volume":"51","author":"T Boyer","year":"2010","journal-title":"Hepatology"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"135","DOI":"10.3109\/08860229509026250","article-title":"Risk factors and outcome of 107\u00a0patients with decompensated liver disease and acute renal failure (including 26 patients with hepatorenal syndrome): The role of hemodialysis","volume":"17","author":"F Keller","year":"1995","journal-title":"Renal Failure"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1007\/s11255-013-0527-7","article-title":"Management and outcome in hepatorenal syndrome: need for renal replacement therapy in non-transplanted patients","volume":"46","author":"A Sourianarayanane","year":"2014","journal-title":"Int Urol Nephrol"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1111\/liv.13389","article-title":"Renal replacement therapy in critically ill liver cirrhotic patients \u2013 outcome and clinical implications","volume":"37","author":"K Staufer","year":"2017","journal-title":"Liver International"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"1369","DOI":"10.1111\/j.1440-1746.2004.03471.x","article-title":"Which patients benefit from hemodialysis therapy in hepatorenal syndrome?","volume":"19","author":"O Witzke","year":"2005","journal-title":"J Gastroenterol Hepatol"}],"container-title":["Zeitschrift f\u00fcr Gastroenterologie"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-1369-9859.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,12]],"date-time":"2021-04-12T23:31:50Z","timestamp":1618270310000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-1369-9859"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2,25]]},"references-count":11,"journal-issue":{"issue":"04","published-online":{"date-parts":[[2021,4,12]]},"published-print":{"date-parts":[[2021,4]]}},"URL":"https:\/\/doi.org\/10.1055\/a-1369-9859","relation":{},"ISSN":["0044-2771","1439-7803"],"issn-type":[{"value":"0044-2771","type":"print"},{"value":"1439-7803","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,2,25]]}}}