{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T19:15:15Z","timestamp":1774379715875,"version":"3.50.1"},"reference-count":48,"publisher":"Georg Thieme Verlag KG","issue":"06","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Fortschr Neurol Psychiatr"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>In dieser \u00dcbersichtsarbeit wurden aktuelle Angaben zu H\u00e4ufigkeit und Relevanz chemosensorischer St\u00f6rungen bei Covid-19 erfasst, pathophysiologisch zugeordnet und Aussagen zur prognostischen Bedeutung abgeleitet. Die Ergebnisse basieren auf einer umfassenden Literaturrecherche s\u00e4mtlicher Literatur zu diesem Thema und eigenen Erfahrungen in der Behandlung von Patienten mit Riech- und Schmeckst\u00f6rungen seit dem Beginn der Pandemie.<\/jats:p><jats:p>Bisherige Studienergebnisse deuten darauf hin, dass klinisch gering betroffene Covid-19-Patienten ohne station\u00e4re Behandlungs- und Beatmungspflicht h\u00e4ufig St\u00f6rungen der Chemosensorik aufweisen. Insbesondere bei jungen Patienten und Frauen scheinen sie ein Indikator einer g\u00fcnstigen Prognose des Krankheitsverlaufs zu sein. Riechst\u00f6rungen k\u00f6nnen fr\u00fch, isoliert oder als eines von mehreren Symptomen einer Covid-19-Erkrankung auftreten. Ob eine Ageusie eigenst\u00e4ndig auftreten kann oder aber im Rahmen der Anosmie mit empfunden wird, ist noch nicht gekl\u00e4rt. In der Pandemie ist das neue Auftreten einer Anosmie ohne Kongestion\u200a\/\u200aObstruktion\/Schnupfen wahrscheinlich Ausdruck einer Infektion mit SARS-CoV-2 und sollte stets zu Quarant\u00e4ne und Testung auf SARS-CoV-2 Anlass geben. Die Riechst\u00f6rung bei Covid-19 scheint meist vor\u00fcbergehend zu sein; ob es regelhaft zu einer vollst\u00e4ndigen Restitution kommt, kann noch nicht abschlie\u00dfend beurteilt werden. Die bereits bei anderen postviralen Riechst\u00f6rungen etablierten Therapieans\u00e4tze (z.\u200aB. Riechtraining) kommen auch hier zum Einsatz.<\/jats:p>","DOI":"10.1055\/a-1375-0761","type":"journal-article","created":{"date-parts":[[2021,2,24]],"date-time":"2021-02-24T00:00:44Z","timestamp":1614124844000},"page":"281-288","source":"Crossref","is-referenced-by-count":10,"title":["St\u00f6rungen der Chemosensorik bei Covid-19: Pathomechanismen und klinische Relevanz"],"prefix":"10.1055","volume":"89","author":[{"given":"Stefan","family":"Isenmann","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Neurologie und klinische Neurophysiologie, St. Josef Krankenhaus Moers"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1311-8000","authenticated-orcid":false,"given":"Antje","family":"Haehner","sequence":"additional","affiliation":[{"name":"Interdisziplin\u00e4res Zentrum f\u00fcr Riechen und Schmecken, Klinik f\u00fcr HNO-Heilkunde, Universit\u00e4tsklinikum Carl Gustav Carus, TU Dresden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Hummel","sequence":"additional","affiliation":[{"name":"Interdisziplin\u00e4res Zentrum f\u00fcr Riechen und Schmecken, Klinik f\u00fcr HNO-Heilkunde, Universit\u00e4tsklinikum Carl Gustav Carus, TU Dresden"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2021,2,23]]},"reference":[{"issue":"01","key":"ref1","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1093\/chemse\/bjp083","article-title":"An initial evaluation of the functions of human olfaction","volume":"35","author":"RJ Stevenson","year":"2010","journal-title":"Chem Senses"},{"issue":"01","key":"ref2","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/0092-8674(91)90418-X","article-title":"A novel multigene family may encode odorant receptors: a molecular basis for odor recognition","volume":"65","author":"L Buck","year":"1991","journal-title":"Cell"},{"key":"ref3","first-page":"1","article-title":"Riechst\u00f6rungen: H\u00e4ufig im Alter und wichtiges Fr\u00fchsymptom","volume":"110","author":"KB H\u00fcttenbrink","year":"2013","journal-title":"Dtsch Arztebl Int"},{"key":"ref4","first-page":"1787","volume-title":"Anosmie und Influenza (Ein rhinologischer Beitrag zur Differentialdiagnose der Erk\u00e4ltungskrankheiten). 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