{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,30]],"date-time":"2022-03-30T09:50:37Z","timestamp":1648633837880},"reference-count":24,"publisher":"Georg Thieme Verlag KG","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Laryngorhinootologie"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Die Aktinomykose ist eine durch grampositive, fakultativ anaerobe Bakterien verursachte Infektionskrankheit, die sich in den meisten F\u00e4llen im zervikofazialen Bereich manifestiert und oft einen dentogenen Fokus aufweist. Das klinische Bild reicht vom akuten Abszessgeschehen bis zu chronisch fistulierenden Gewebeprozessen. Eine fr\u00fchzeitige Diagnose und ein angemessenes therapeutisches Vorgehen mit einer Kombination aus ausgedehnter antibiotischer Behandlung und ggf. chirurgischer Sanierung sind f\u00fcr einen g\u00fcnstigen Krankheitsverlauf entscheidend. In diesem Artikel werden 5 F\u00e4lle von Aktinomyzeteninfektionen dargestellt, welche die Vielfalt der klinischen Erscheinungsbilder, die Problematik auf dem Weg zur richtigen Diagnose und m\u00f6gliche Therapieverl\u00e4ufe illustrieren sollen.<\/jats:p>","DOI":"10.1055\/a-1381-8406","type":"journal-article","created":{"date-parts":[[2021,2,22]],"date-time":"2021-02-22T23:57:56Z","timestamp":1614038276000},"page":"966-972","source":"Crossref","is-referenced-by-count":0,"title":["Zervikofaziale Aktinomykose"],"prefix":"10.1055","volume":"100","author":[{"given":"Anja Maria","family":"Brosig","sequence":"additional","affiliation":[{"name":"Klinik und Poliklinik f\u00fcr Hals-Nasen-Ohren-Heilkunde, Universit\u00e4tsklinikum Regensburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Florian","family":"Hitzenbichler","sequence":"additional","affiliation":[{"name":"Abteilung f\u00fcr Krankenhaushygiene und Infektiologie, Universit\u00e4tsklinikum Regensburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benjamin","family":"Ernst","sequence":"additional","affiliation":[{"name":"Hals-Nasen-Ohrenklinik und Poliklinik, Johannes-Gutenberg-Universit\u00e4t Mainz, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Josef","family":"K\u00f6stler","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Mikrobiologie und Hygiene, Universit\u00e4tsklinikum Regensburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher","family":"Bohr","sequence":"additional","affiliation":[{"name":"Klinik und Poliklinik f\u00fcr Hals-Nasen-Ohren-Heilkunde, Universit\u00e4tsklinikum Regensburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julian","family":"K\u00fcnzel","sequence":"additional","affiliation":[{"name":"Klinik und Poliklinik f\u00fcr Hals-Nasen-Ohren-Heilkunde, Universit\u00e4tsklinikum Regensburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2021,2,22]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"e627","DOI":"10.4317\/medoral.19124","article-title":"Treatment of cervicofacial actinomycosis: a report of 19 cases and review of literature","volume":"18","author":"M Moghimi","year":"2013","journal-title":"Medicina oral, patologia oral y cirugia bucal"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"9","DOI":"10.3390\/antibiotics9040139","article-title":"Diagnosis and Management of Cervicofacial Actinomycosis: Lessons from Two Distinct Clinical Cases","author":"A St\u00e1jer","year":"2020","journal-title":"Antibiotics (Basel, Switzerland)"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"31604","DOI":"10.1038\/srep31604","article-title":"The association of medication-related osteonecrosis of the jaw with Actinomyces spp","volume":"6","author":"G Russmueller","year":"2016","journal-title":"infection. 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