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Overall, the maternal prognosis is good. The fetal outcome depends on the bile acid level. ICP is associated with increased risks for adverse perinatal outcomes, including preterm delivery, meconium-stained amniotic fluid, and stillbirth. Acute fetal asphyxia and not chronic uteroplacental dysfunction leads to stillbirth. Therefore, predictive fetal monitoring is not possible. While medication with ursodeoxycholic acid (UDCA) improves pruritus, it has not been shown to affect fetal outcome. The indication for induction of labour depends on bile acid levels and gestational age. There is a high risk of recurrence in subsequent pregnancies.<\/jats:p>","DOI":"10.1055\/a-1386-3912","type":"journal-article","created":{"date-parts":[[2021,8,10]],"date-time":"2021-08-10T00:01:34Z","timestamp":1628553694000},"page":"922-939","source":"Crossref","is-referenced-by-count":25,"title":["Management of Intrahepatic Cholestasis of Pregnancy: Recommendations of the Working Group on Obstetrics and Prenatal Medicine \u2013 Section on Maternal Disorders"],"prefix":"10.1055","volume":"81","author":[{"given":"Carsten","family":"Hagenbeck","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinikum D\u00fcsseldorf, Frauenklinik, D\u00fcsseldorf, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amr","family":"Hamza","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinikum des Saarlandes, Klinik f\u00fcr Frauenheilkunde, Geburtshilfe und Reproduktionsmedizin, Homburg, Germany"},{"name":"Kantonsspital Baden AG, Baden, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sven","family":"Kehl","sequence":"additional","affiliation":[{"name":"Frauenklinik, Friedrich Alexander University Erlangen Nuremberg, Faculty of Medicine, Erlangen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Holger","family":"Maul","sequence":"additional","affiliation":[{"name":"Section of Prenatal Disgnostics and Therapy, Asklepios Klinik Barmbek, Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Lammert","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Innere Medizin II, Universit\u00e4tsklinikum des Saarlandes und Medizinische Fakult\u00e4t der Universit\u00e4t des Saarlandes, Homburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Verena","family":"Keitel","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinikum D\u00fcsseldorf, Klinik f\u00fcr Gastroenterologie, 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