{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T13:27:41Z","timestamp":1787318861145,"version":"build-2736575974"},"reference-count":30,"publisher":"Georg Thieme Verlag KG","issue":"02","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Endoscopy"],"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Background\u2002During endoscopic retrograde cholangiopancreatography (ERCP), access to the common bile duct (CBD) can be problematic after unintentional insertion of the guidewire into the pancreatic duct. We conducted a prospective, randomized study in order to compare biliary cannulation success rates of early double-guidewire (EDG) and repeated single-guidewire (RSG) techniques in patients with inadvertent passage of the guidewire into the pancreatic duct.<\/jats:p>\n                  <jats:p>Methods\u2002Patients with a native papilla were randomly assigned to either the EDG or RSG groups after unintentional insertion of the guidewire into the pancreatic duct. The primary outcome was successful selective CBD cannulation within 10 minutes. The secondary outcomes were successful final selective bile duct cannulation, time to bile duct cannulation, and frequency of post-ERCP pancreatitis (PEP).<\/jats:p>\n                  <jats:p>Results\u2002142 patients were randomized and selective bile duct cannulation was achieved in 57\/68 patients (84\u200a%) in the EDG group and in 37\/74 patients (50\u200a%) in the RSG group within 10 minutes (relative risk 1.34; 95\u200a% confidence interval 1.08\u20136.18; P\u200a&lt;\u200a0.001). The overall final selective bile duct cannulation rate was 99.3\u200a%. The time to access the CBD was shorter using the EDG technique (6.0 vs. 10.4 minutes; P\u200a=\u200a0.002). Mild PEP was not observed more frequently in the EDG group than in the RSG group.<\/jats:p>\n                  <jats:p>Conclusion\u2002The EDG technique significantly increased the success rate of biliary duct cannulation within 10 minutes compared with an RSG approach.<\/jats:p>","DOI":"10.1055\/a-1395-7485","type":"journal-article","created":{"date-parts":[[2021,4,16]],"date-time":"2021-04-16T03:03:25Z","timestamp":1618542205000},"page":"120-127","source":"Crossref","is-referenced-by-count":24,"title":["Early double-guidewire versus repeated single-guidewire technique to facilitate selective bile duct cannulation: a randomized controlled trial"],"prefix":"10.1055","volume":"54","clinical-trial-number":[{"clinical-trial-number":"nct03582540","registry":"10.18810\/clinical-trials-gov"}],"author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8805-4454","authenticated-orcid":false,"given":"Arthur","family":"Laqui\u00e8re","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Saint Joseph Hospital, Marseille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jocelyn","family":"Privat","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Jacques Lacarin Hospital, Vichy, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeremie","family":"Jacques","sequence":"additional","affiliation":[{"name":"Department of Endoscopy and Gastroenterology, Dupuytren Hospital, Limoges, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Romain","family":"Legros","sequence":"additional","affiliation":[{"name":"Department of Endoscopy and Gastroenterology, Dupuytren Hospital, Limoges, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Romina","family":"Urena-Campos","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Saint Joseph Hospital, Marseille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hichem","family":"Belkhodja","sequence":"additional","affiliation":[{"name":"Digestive Endoscopy Unit, University Hospital Lyon Sud, Lyon, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cl\u00e9ment","family":"Subtil","sequence":"additional","affiliation":[{"name":"Digestive Endoscopy Unit, University Hospital, Bordeaux, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Le\u00efla","family":"Kanafi","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Groupe Polyclinique Marzet-Navarre, Pau, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurence","family":"Lecomte","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Saint Joseph Hospital, Marseille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Bousti\u00e8re","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Saint Joseph Hospital, Marseille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Katsogiannou","sequence":"additional","affiliation":[{"name":"Department of Clinical Research, Saint Joseph Hospital, Marseille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1487-2814","authenticated-orcid":false,"given":"David","family":"Karsenti","sequence":"additional","affiliation":[{"name":"Digestive Endoscopy Unit, P\u00f4le Digestif Paris Bercy, Clinique Paris-Bercy, Charenton-le-Pont, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2021,4,15]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.gie.2005.04.015","article-title":"ASGE guideline: the role of ERCP in diseases of the biliary tract and the pancreas","volume":"62","author":"D G Adler","year":"2005","journal-title":"Gastrointest Endosc"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/S0016-5107(04)02463-0","article-title":"ERCP cannulation: a review of reported techniques","volume":"61","author":"M L Freeman","year":"2005","journal-title":"Gastrointest Endosc"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1055\/s-0042-108641","article-title":"Papillary cannulation and sphincterotomy techniques at ERCP: European Society of Gastrointestinal Endoscopy (ESGE) Clinical Guideline","volume":"48","author":"P A 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A prospective randomized controlled trial.","volume":"45","author":"K Ito","year":"2010","journal-title":"J Gastroenterol"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"108","DOI":"10.3748\/wjg.v19.i1.108","article-title":"Double guidewire technique vs transpancreatic precut sphincterotomy in difficult biliary cannulation","volume":"19","author":"Y W Yoo","year":"2013","journal-title":"World J Gastroenterol"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1016\/j.gie.2015.09.039","article-title":"Algorithm for the management of ERCP-related perforations","volume":"83","author":"V Kumbhari","year":"2016","journal-title":"Gastrointest Endosc"},{"key":"ref20","first-page":"15","article-title":"Double-guidewire technique in difficult biliary cannulation for the prevention of post-ERCP pancreatitis: a systematic review and meta-analysis","volume":"49","author":"F Tse","year":"2017","journal-title":"Endoscopy"},{"issue":"S 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Gastroenterol"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1055\/s-0034-1377875","article-title":"Prophylaxis of post-ERCP pancreatitis: European Society of Gastrointestinal Endoscopy (ESGE) Guideline \u2013 updated June 2014","volume":"46","author":"J M Dumonceau","year":"2014","journal-title":"Endoscopy"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1111\/den.12779","article-title":"Prophylactic rectal indomethacin may be ineffective for preventing post-endoscopic retrograde cholangiopancreatography pancreatitis in general patients: a meta-analysis","volume":"29","author":"Y Feng","year":"2017","journal-title":"Dig Endosc"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"1144","DOI":"10.1016\/j.gie.2017.01.033","article-title":"Indomethacin and diclofenac in the prevention of post-ERCP pancreatitis: a systematic review and meta-analysis of prospective controlled trials","volume":"85","author":"A Patai","year":"2017","journal-title":"Gastrointest Endosc"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1016\/j.pan.2017.07.008","article-title":"Rectal nonsteroidal anti-inflammatory drugs administration is effective for the prevention of post-ERCP pancreatitis: an updated meta-analysis of randomized controlled trials","volume":"17","author":"C Yang","year":"2017","journal-title":"Pancreatology"}],"container-title":["Endoscopy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-1395-7485.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,27]],"date-time":"2022-01-27T20:30:40Z","timestamp":1643315440000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-1395-7485"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4,15]]},"references-count":30,"journal-issue":{"issue":"02","published-online":{"date-parts":[[2022,1,27]]},"published-print":{"date-parts":[[2022,2]]}},"URL":"https:\/\/doi.org\/10.1055\/a-1395-7485","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0013-726X","1438-8812"],"issn-type":[{"value":"0013-726X","type":"print"},{"value":"1438-8812","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,4,15]]}}}