{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,5,26]],"date-time":"2023-05-26T17:29:09Z","timestamp":1685122149520},"reference-count":45,"publisher":"Georg Thieme Verlag KG","issue":"03","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tierarztl Prax Ausg G Grosstiere Nutztiere"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>\n               Ziel Untersuchung von Abwehrreaktionen, Ferkelverlusten und Aufwachphase unter automatisierter Isoflurannarkose kastrierter Saugferkel, Erhebung von Isoflurankonzentrationen in der Umgebung sowie des Erfolgs von Reinigung und Desinfektion der Narkosemasken.<\/jats:p><jats:p>\n               Material und Methoden Insgesamt 955 m\u00e4nnliche Saugferkel (Alter 4,0 \u00b1 1,2 Tage; Gewicht 2,0 \u00b1 0,5 kg) aus 5 Abferkeldurchg\u00e4ngen (DG) wurden nach Applikation eines nicht steroidalen Antiphlogistikums unter Isoflurannarkose (PorcAnest 3000\u00ae) kastriert. Zur Beurteilung von Reaktionen der Tiere dienten der Zwischenklauenreflex vor sowie Abwehrbewegungen und Laut\u00e4u\u00dferungen w\u00e4hrend der Kastration. Die Aufwachphase wurde im Stallgang (DG 1) bzw. in der Abferkelbucht (DG 4\u20135) evaluiert. Bei 73 Tieren wurde der Samenstrang mit dem Skalpell abgesetzt und Nachblutungen visuell \u00fcberpr\u00fcft. Isofluranmessungen fanden an verschiedenen Lokalisationen statt. Die Narkosemasken wurden vor und nach der Anwendung sowie nach Desinfektion auf Gesamtkeimbelastung und Indikatorkeime untersucht.<\/jats:p><jats:p>\n               Ergebnisse Bei der Kastration wiesen 94,3 % der Saugferkel nach der Einleitungszeit von 90 Sekunden und 95,3 % der Ferkel mit vorheriger Testung des Zwischenklauenreflexes und gegebenenfalls Verl\u00e4ngerung der Isofluranzufuhr keine oder nur eine kurze Abwehrbewegung auf. Bei 0,9 % der Ferkel trat ein Narkosezwischenfall auf, kein Tier verendete. Die Aufwachphase dauerte 7,3 \u00b1 4,7 Minuten (DG 1) bzw. 6,2 \u00b1 3,3 Minuten (DG 4\u20135). Das Absetzen des Samenstrangs mittels Skalpells f\u00fchrte zu einem h\u00f6heren Nachblutungsscore (p &lt; 0,001) als die Anwendung des Emaskulators. Die Isoflurankonzentrationen in der Umgebungsluft lagen zwischen 4,5 und 28,1 mg\/m3. Die Maskendesinfektion reduzierte die Gesamtkeimzahl um 99,8 %. Kontaminationen mit Escherichia coli und MRSA waren in 4 von 6 F\u00e4llen nach Desinfektion nicht mehr nachweisbar.<\/jats:p><jats:p>\n               Schlussfolgerung Die Isoflurannarkose f\u00fchrte bei \u00fcber 94 % der Ferkel zu keiner bzw. einer geringgradigen Abwehrreaktion w\u00e4hrend der Kastration. Narkosezwischenf\u00e4lle waren selten und hatten keine vermehrten Ferkelverluste zur Folge. Somit ist die automatisierte Isoflurannarkose bei sorgf\u00e4ltiger Anwendung mit einem geringen Risiko f\u00fcr die Saugferkel verbunden. Die Isoflurankonzentration in der Atemluft der beteiligten Personen lag unter dem international niedrigsten Grenzwert. Die Desinfektion der Narkosemasken k\u00f6nnte eine Keim\u00fcbertragung zwischen Tiergruppen \u00fcber diesen potenziellen Vektor verhindern.<\/jats:p>","DOI":"10.1055\/a-1396-3113","type":"journal-article","created":{"date-parts":[[2021,6,22]],"date-time":"2021-06-22T22:32:46Z","timestamp":1624401166000},"page":"167-177","source":"Crossref","is-referenced-by-count":3,"title":["Untersuchungen zur automatisierten Isoflurannarkose bei der Saugferkelkastration"],"prefix":"10.1055","volume":"49","author":[{"given":"Helena","family":"H\u00e4rtel","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Schweine, Zentrum f\u00fcr Klinische Tiermedizin, Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sophie","family":"Gumbert","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Schweine, Zentrum f\u00fcr Klinische Tiermedizin, Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Rauh","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Schweine, Zentrum f\u00fcr Klinische Tiermedizin, Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marina","family":"Beisl","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Schweine, Zentrum f\u00fcr Klinische Tiermedizin, Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jochen","family":"Schulz","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Tierhygiene, Tierschutz und Nutztierethologie, Stiftung Tier\u00e4rztliche Hochschule Hannover"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katrin","family":"Kempf","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Tierhygiene, Tierschutz und Nutztierethologie, Stiftung Tier\u00e4rztliche Hochschule Hannover"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steffanie","family":"Senf","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Schweine, Zentrum f\u00fcr Klinische Tiermedizin, Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eva","family":"Winner","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Schweine, Zentrum f\u00fcr Klinische Tiermedizin, Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine","family":"Wei\u00df","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Schweine, Zentrum f\u00fcr Klinische Tiermedizin, Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"N\u00fc\u00dflein","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Landtechnik und Tierhaltung, Bayerische Landesanstalt f\u00fcr Landwirtschaft, Schwarzach am Main"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yury","family":"Zablotski","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Schweine, Zentrum f\u00fcr Klinische Tiermedizin, Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mathias","family":"Ritzmann","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Schweine, Zentrum f\u00fcr Klinische Tiermedizin, Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susanne","family":"Z\u00f6ls","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Schweine, Zentrum f\u00fcr Klinische Tiermedizin, Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2021,6,22]]},"reference":[{"key":"ref2","first-page":"1218","article-title":"Saugferkelkastration unter Lokalan\u00e4sthesie?","volume":"9","author":"K H Waldmann","year":"2018","journal-title":"Dtsch Tier\u00e4rztebl"},{"key":"ref3","first-page":"17","volume-title":"Allgemeinan\u00e4sthetika","author":"W Erhardt","year":"2012","edition":"2. 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