{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T18:06:25Z","timestamp":1758477985769},"reference-count":22,"publisher":"Georg Thieme Verlag KG","issue":"08","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Z Gastroenterol"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background\u2002We aimed to determine the prevalence and incidence of gallbladder stones in a random population-based collective in Germany.<\/jats:p><jats:p>\n          Methods\u2002We determined the prevalence and incidence rates of gallbladder stones in a random population sample of 1909 individuals from the Echinococcus-multilocularis in Leutkirch (EMIL) study in 2002 and 380 individuals in a follow-up analysis in the year 2013. The sonographic analysis was performed with a Philipps HDI 5000 (2002) and IU 22 (2013) (Netherlands) transducer 1\u20135\u200aMHz. Statistical analysis was performed using SAS Version 9.4.<\/jats:p><jats:p>\n          Results\u2002The prevalence of gallbladder stones was 3.8\u200a% (69\/1909) in 2002 and 10.8\u200a% (41\/380) in 2013. In 2013, the gallbladder stone prevalence was 15.1\u200a% (26\/172) in women, compared to 7.2\u200a% (15\/208) in men. No gallbladder stones were found in participants in the 18\u201330 or 31\u201340 age groups. The average annual incidence was 1.03\u200a% in the 41\u201350 age group, 0.79\u200a% in the 51\u201365 age group, and 0.63\u200a% in the &gt;\u200a65\u00a0age group.\u200aThe annual incidence was higher among women (1.04\u200a%) than men (0.53\u200a%). The age-associated annual incidence rates for women and men were 1.93\u200a% and\u00a00.5\u200a% in the 41\u201350 age group, 0.8\u200a% and 0.78\u200a% in the 51\u201365 age group, and 1.06\u200a% and 0.30\u200a% in the &gt;\u200a65 age group.<\/jats:p><jats:p>\n          Conclusion\u2002For the investigated German collective from 2002 to 2013, the average annual incidence of gallbladder stones was 0.75\u200a%, with a higher incidence rate among women. These results are consistent with data from comparable international studies.<\/jats:p>","DOI":"10.1055\/a-1401-2170","type":"journal-article","created":{"date-parts":[[2021,3,17]],"date-time":"2021-03-17T00:12:36Z","timestamp":1615939956000},"page":"859-864","source":"Crossref","is-referenced-by-count":7,"title":["Gallbladder stone incidence and prevalence in Germany: a\u00a0population-based study"],"prefix":"10.1055","volume":"59","author":[{"given":"Wolfgang","family":"Kratzer","sequence":"first","affiliation":[{"name":"Klinik f\u00fcr Innere Medizin I, Universit\u00e4tsklinikum Ulm"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Magdalena","family":"Klysik","sequence":"first","affiliation":[{"name":"Klinik f\u00fcr Innere Medizin I, Universit\u00e4tsklinikum Ulm"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"Binzberger","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Innere Medizin I, Universit\u00e4tsklinikum Ulm"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julian","family":"Schmidberger","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Innere Medizin I, Universit\u00e4tsklinikum Ulm"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"for the EMIL-Study group","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2021,3,16]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"148","DOI":"10.3238\/arztebl.2020.0148","article-title":"The treatment of gallstone disease","volume":"117","author":"C Gutt","year":"2020","journal-title":"Dtsch Arztebl Int"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"912","DOI":"10.1055\/a-0644-2972","article-title":"[Updated S3-Guideline for Prophylaxis, Diagnosis and Treatment of Gallstones. 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