{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T08:33:50Z","timestamp":1740126830859,"version":"3.37.3"},"reference-count":44,"publisher":"Georg Thieme Verlag KG","issue":"06","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Handchir Mikrochir Plast Chir"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Der tiefe sternale Wundinfekt (TSWI) ist eine seltene Komplikation nach Sternotomie, die mit hoher Morbidit\u00e4t und Mortalit\u00e4t behaftet ist und Krankenhausaufenthalt sowie die Behandlungskosten signifikant ansteigen l\u00e4sst. Eine mikrobiologische Besonderheit ist die Ausbildung von Biofilmen auf Implantatmaterial und\/oder Knochensequestern. Die Diagnose wird anhand der klinischen Symptomatik der lokalen Entz\u00fcndungsreaktion gestellt und durch systemische Infektionszeichen gest\u00fctzt. Eine fr\u00fchzeitige und gemeinsame Konsensfindung, welche die oft interdisziplin\u00e4re Behandlungsstrategie festlegt, ist dabei essenziell. Die Behandlung besteht i.\u2009d.\u2009R.\u2005aus mehreren chirurgischen Wunddebridements mit zwischenzeitlicher Wundkonditionierung, bis ein ausreichend sauberer Wundstatus erreicht ist. Zur Infektsanierung und f\u00fcr den Wundverschluss stehen je nach Gr\u00f6\u00dfe und Lokalisation des Gewebedefektes eine Vielzahl verschiedener gestielter und freier Lappenplastiken zur Auswahl.<\/jats:p>","DOI":"10.1055\/a-1425-5987","type":"journal-article","created":{"date-parts":[[2021,5,5]],"date-time":"2021-05-05T22:38:22Z","timestamp":1620254302000},"page":"519-525","source":"Crossref","is-referenced-by-count":2,"title":["Der tiefe sternale Wundinfekt nach Sternotomie"],"prefix":"10.1055","volume":"53","author":[{"given":"Yves","family":"Harder","sequence":"first","affiliation":[{"name":"Klinik f\u00fcr Plastische, Rekonstruktive und \u00c4sthetische Chirurgie, Ospedale Regionale di Lugano (ORL), Ente Ospedaliero Cantonale (EOC), Lugano, Schweiz"},{"name":"Faculty of Biomedical Sciences, Universit\u00e0 della Svizzera Italiana, Lugano, 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