{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,2,27]],"date-time":"2024-02-27T17:48:49Z","timestamp":1709056129056},"reference-count":45,"publisher":"Georg Thieme Verlag KG","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rofo"],"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:p>\n            Background\u2002Normal pressure hydrocephalus is a disease in elderly patients and one of the most common causes of treatable dementia. It occurs frequently with microangiopathy and Alzheimer\u2019s disease, so that differential diagnosis plays an important role. This is crucially determined by imaging findings. Therapy consists of cerebrospinal fluid drainage through a shunt, which should be performed as early as possible to improve the chances of success.<\/jats:p><jats:p>\n            Method\u2002This report is based on a summary of the relevant literature that has been reviewed in PubMed with reference to epidemiology, symptoms, pathophysiology, diagnostics, and therapy. The results were supplemented by the joint guidelines of the German Society of Neurology and the German Society of Neurosurgery.<\/jats:p><jats:p>\n            Results and Conclusion\u2002The understanding of the pathophysiologic changes leading to normal pressure hydrocephalus has expanded significantly in recent years to include concepts explaining relevant comorbidities. Diagnosis is based on radiological and clinical indicators, although accurate differentiation with respect to comorbidities is not always possible. A high response rate to treatment can be achieved by good patient selection. Positive prognostic markers for therapeutic success include Disproportionately Enlarged Subarachnoid Space Hydrocephalus (DESH), short disease duration, predominant gait disturbance, and few comorbidities.<\/jats:p><jats:p>\n            Key Points:\u2002<\/jats:p><jats:p>\n            Citation Format\n          <\/jats:p>","DOI":"10.1055\/a-1425-8065","type":"journal-article","created":{"date-parts":[[2021,9,16]],"date-time":"2021-09-16T23:22:37Z","timestamp":1631834557000},"page":"1197-1206","source":"Crossref","is-referenced-by-count":2,"title":["What Radiologists Should Know About Normal Pressure Hydrocephalus"],"prefix":"10.1055","volume":"193","author":[{"given":"Till","family":"Illies","sequence":"additional","affiliation":[{"name":"Fachbereich Neuroradiologie, Asklepios Klinik Altona, Hamburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernd","family":"Eckert","sequence":"additional","affiliation":[{"name":"Fachbereich Neuroradiologie, Asklepios Klinik Altona, Hamburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Uwe","family":"Kehler","sequence":"additional","affiliation":[{"name":"Abt. f. Neurochirurgie, Asklepios Klinik Altona, Hamburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2021,9,16]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/0022-510X(65)90016-X","article-title":"The special clinical problem of symptomatic hydrocephalus with normal cerebrospinal fluid pressure. Observations on cerebrospinal fluid hydrodynamics","volume":"2","author":"S Hakim","year":"1965","journal-title":"J Neurol Sci"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1056\/NEJM196507152730301","article-title":"Symptomatic Occult Hydrocephalus with \u201cNormal\u201d Cerebrospinal-Fluid Pressure. 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