{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T21:57:34Z","timestamp":1782511054864,"version":"3.54.5"},"reference-count":28,"publisher":"Georg Thieme Verlag KG","issue":"04","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Klin Padiatr"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Background The prevalence of hypernatremic dehydration (HND) has increased in recent years most likely due to insufficient intake of breast milk as the most important factor. This study aimed to investigate risk factors of HND.<\/jats:p><jats:p>Methods In this study, 47 neonates whom were diagnosed to have HND were included in the study group and 96 healty neonates whom were included in the control group. While demographic data of the patients were recorded, mothers were asked to fill out the sociodemographic\/ psychosocial data form, Edinburgh Postpartum Depression Scale(EPDS) and STAI I and II State and Trait Anxiety Scale. Breast milk sodium concentrations were studied from mothers of all infants. The relationship between the development of neonatal HND and risk factors affecting this condition were evaluated.<\/jats:p><jats:p>Results Being the first-born baby of the family was found to be a significant risk factor for HND. Breast milk sodium concentration was 25.8\u00b17.9 mmol\/L in the HND group which was significantly higher than the control group. Median depression score was similar in both groups and there was no statistical difference in terms of groups. The anxiety score was higher in the control group compared to the study group. There was no difference in terms of other sociodemographic \/ psychosocial data of mothers.<\/jats:p><jats:p>Conclusion Primiparity or insufficient breastfeeding may result in elevated breast milk sodium levels and related neonatal HND. Breastfeeding support should principally target primiparous women to improve breastfeeding outcomes like as especially HND.<\/jats:p>","DOI":"10.1055\/a-1443-6017","type":"journal-article","created":{"date-parts":[[2021,7,21]],"date-time":"2021-07-21T23:00:21Z","timestamp":1626908421000},"page":"194-199","source":"Crossref","is-referenced-by-count":3,"title":["Hypernatremic Dehydration Risk Factors in Newborns: Prospective Case-Controlled Study"],"prefix":"10.1055","volume":"233","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4522-6885","authenticated-orcid":false,"given":"Kiymet","family":"Celik","sequence":"additional","affiliation":[{"name":"Neonatology, Akdeniz University, Antalya, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aylin","family":"Ozbek","sequence":"additional","affiliation":[{"name":"Child and Adolescent Psychiatry, Dokuz Eyl\u00fcl University, IZMIR, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ozgur","family":"Olukman","sequence":"additional","affiliation":[{"name":"Neonatology, Dr Behcet Uz Child Disease and Surgery Training and Research Hospital, Izmir, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Figen","family":"Isleten","sequence":"additional","affiliation":[{"name":"Biochemistry, Dr Behcet Uz Child Disease and Surgery Training and Research Hospital, Izmir, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebnem","family":"Calkavur","sequence":"additional","affiliation":[{"name":"Neonatology, Dr Behcet Uz Child Disease and Surgery Training and Research Hospital, Izmir, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2021,7,21]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"e0167313","DOI":"10.1371\/journal.pone.0167313","article-title":"Evidence Based Weighing Policy during the First Week to Prevent Neonatal Hypernatremic Dehydration while Breastfeeding","volume":"11","author":"S Boer","year":"2016","journal-title":"PLoS One"},{"key":"ref2","first-page":"301","article-title":"Neonatal hypernatremia and dehydration in infants receiving inadequate breastfeeding","volume":"19","author":"H Boskabadi","year":"2010","journal-title":"Asia Pac J Clin Nutr"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1590\/S0100-879X2006000400015","article-title":"Risk factors for excess weight loss and hypernatremia in exclusively breast-fed infants","volume":"39","author":"M K Caglar","year":"2006","journal-title":"Braz J Med Biol Res"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1192\/bjp.150.6.782","article-title":"Detection of postnatal depression, Development of the 10 items Edinburgh postnatal depression scale","volume":"150","author":"J L Cox","year":"1987","journal-title":"Br J Psychiatry"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1542\/peds.112.3.607","article-title":"Risk factors for suboptimal infant breastfeeding behavior, delayed onset of lactation, and excess neonatal weight loss","volume":"112","author":"K G Dewey","year":"2003","journal-title":"Pediatrics."},{"key":"ref6","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1177\/0890334416662241","article-title":"Postpartum Anxiety and Infant-Feeding Outcomes","volume":"32","author":"V Fallon","year":"2016","journal-title":"J Hum Lact"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1067\/mob.2002.123404","article-title":"Diagnosing postpartum depression: can we do better?","volume":"186","author":"S S Fergerson","year":"2002","journal-title":"Am J Obstet Gynecol"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1177\/0890334405280947","article-title":"Symptoms of postpartum depression and breastfeeding","volume":"21","author":"D C Hatton","year":"2005","journal-title":"J Hum Lact"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1007\/s00431-008-0841-8","article-title":"Prevention of hypernatraemic dehydration in breastfed newborn infants by daily weighing","volume":"168","author":"G Konetzny","year":"2009","journal-title":"Eur J Pediatr"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1136\/adc.57.7.500","article-title":"Breast milk sodium","volume":"57","author":"W W Koo","year":"1982","journal-title":"Arch Dis Child"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1089\/bfm.2016.0213","article-title":"Associations Between Postpartum Depression, Breastfeeding, and Oxytocin Levels in Latina Mothers","volume":"12","author":"S Lara-Cinisomo","year":"2017","journal-title":"Breastfeed Med"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1177\/0890334415613079","article-title":"Breastfeeding-Associated Hypernatremia: A Systematic Review of the Literature","volume":"32","author":"C Lavagno","year":"2016","journal-title":"J Hum Lact"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1067\/mpd.2001.118880","article-title":"Incidence of dehydration and hypernatremia in exclusively breast-fed infants","volume":"139","author":"R Manganaro","year":"2001","journal-title":"J Pediatr"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1159\/000360323","article-title":"Breastfeeding","volume":"113","author":"K F Michaelsen","year":"2015","journal-title":"World Rev Nutr Diet"},{"key":"ref15","first-page":"731","article-title":"Initial management of hypernatremic dehydration in the breastfed infant","volume":"33","author":"K H Molteni","year":"1994","journal-title":"Clin Pediatr (Phila)"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"1687","DOI":"10.1007\/s00467-005-1933-6","article-title":"Preventing neurological complica- tions from dysnatremias in children","volume":"20","author":"M L Moritz","year":"2005","journal-title":"Pediatr Nephrol"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/S0031-3955(08)70026-9","article-title":"Prevention of breastfeeding tragedies","volume":"48","author":"M R Neifert","year":"2001","journal-title":"Pediatr Clin North Am"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/S0031-3955(05)70284-4","article-title":"Lactogenesis","volume":"48","author":"M C Neville","year":"2001","journal-title":"Pediatr Int Clin North Am"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1136\/adc.85.4.318","article-title":"Hypernatraemic dehydration and breastfeeding: a population study","volume":"85","author":"S Oddie","year":"2001","journal-title":"Arch Dis Child"},{"key":"ref20","volume-title":"State-Trait Anxiety Inventory Handbook","author":"N Oner","year":"1983","edition":"2nd edn."},{"key":"ref21","doi-asserted-by":"crossref","first-page":"361","DOI":"10.18621\/eurj.373386","article-title":"The relationship between hypernatremia and breast milk sodium levels in newborns with hypernatremic dehydration","volume":"5","author":"L T Orgun","year":"2019","journal-title":"Eur Res J"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1111\/j.1440-1754.2007.01208.x","article-title":"Maternal psychosocial aspects of hypernatremic dehydration with high sodium concentrations in breast milk: a case-control study","volume":"44","author":"A Ozbek","year":"2008","journal-title":"Paediatr Child Health"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"F349","DOI":"10.1136\/fn.88.4.F349-a","article-title":"Hypernatraemic dehydration: excess sodium is not the cause","volume":"88","author":"S Richmond","year":"2003","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.1111\/j.1365-2648.2012.06112.x","article-title":"Postpartum depression: the (in) experience of Brazilian primary healthcare professionals","volume":"69","author":"H P Santos Junior","year":"2013","journal-title":"J Adv Nurs"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1177\/0300060517700013","article-title":"Do mothers have high depression and anxiety scores?","volume":"45","author":"B Serim Demirgoren","year":"2017","journal-title":"J Int Med Res"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1016\/j.jped.2016.08.005","article-title":"Association between postpartum depression and the first three months of life","volume":"93","author":"C S Silva","year":"2017","journal-title":"J Pediatr (Rio J)"},{"key":"ref27","volume-title":"Manual for the State-Trait Anxiety Inventory (Form \u2013Y)","author":"C D Spielberger","year":"1983"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1111\/j.1442-200X.2007.02507.x","article-title":"Breast-feeding-associated hypernatremia: retrospective analysis of 169 term newborns","volume":"50","author":"S Unal","year":"2008","journal-title":"Pediatr Int"}],"container-title":["Klinische P\u00e4diatrie"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-1443-6017.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,6]],"date-time":"2023-11-06T09:54:03Z","timestamp":1699264443000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-1443-6017"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7]]},"references-count":28,"journal-issue":{"issue":"04","published-online":{"date-parts":[[2021,7,20]]},"published-print":{"date-parts":[[2021,7]]}},"URL":"https:\/\/doi.org\/10.1055\/a-1443-6017","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0300-8630","1439-3824"],"issn-type":[{"value":"0300-8630","type":"print"},{"value":"1439-3824","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,7]]}}}