{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,10,12]],"date-time":"2022-10-12T00:18:52Z","timestamp":1665533932616},"reference-count":8,"publisher":"Georg Thieme Verlag KG","issue":"07","license":[{"start":{"date-parts":[[2021,6,17]],"date-time":"2021-06-17T00:00:00Z","timestamp":1623888000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Endosc Int Open"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background and study aims\u2002In the last decade, gastroenterologists have been attempting to use endoscopy to reproduce the great success of traditional surgical suture techniques. Despite recent advances, we still lack a reliable method that results in a permanent suture with minimal incidence of suture failure. This was an experimental study in pigs with an innovative technique that applied basic surgical concepts to endoscopy to evaluate the effectiveness of a novel suture technique.<\/jats:p><jats:p>\n          Methods\u2002The procedures were performed on six live pigs under general anesthesia. Endoscopic mucosal resection (EMR) first was performed in the stomach, exposing the submucosal or muscularis propria layers. A novel device, a transparent chamber cap (DASE), was developed to aspirate the gastric wall, allowing the sutures to reach deep layers. The aspiration was performed with a standard gastroscope to which the novel cap was distally attached. Three sutures aligned were defined as a plication. Each pig received two or three plications and was placed on a liquid diet for 14 days after the procedure. The pigs were sacrificed at 4 and 8 weeks and the sutures were reviewed.<\/jats:p><jats:p>\n          Results\u2002The technique was feasible in all animals. Of 16 plications, only one failed. One perforation occurred after EMR. There were no other complications or adverse events. Permanent fusion of the gastric wall was confirmed by histology in all cases.<\/jats:p><jats:p>\n          Conclusions\u2002This study showed that basic principles of surgery can be applied endoscopically to ensure a permanent suture with reduced chances of failure. These findings can help to pave the way for more effective bariatric endoscopic techniques.<\/jats:p>","DOI":"10.1055\/a-1451-3854","type":"journal-article","created":{"date-parts":[[2021,6,17]],"date-time":"2021-06-17T22:30:17Z","timestamp":1623969017000},"page":"E1049-E1054","source":"Crossref","is-referenced-by-count":1,"title":["Applying basic principles of surgery may pave the way for more effective endoscopic bariatric techniques"],"prefix":"10.1055","volume":"09","author":[{"given":"Kiyoshi","family":"Hashiba","sequence":"additional","affiliation":[{"name":"Department of Digestive Endoscopy, Hospital S\u00edrio-Liban\u00eas, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos Alberto","family":"Cappellanes","sequence":"additional","affiliation":[{"name":"Department of Digestive Endoscopy, Hospital S\u00edrio-Liban\u00eas, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pablo Rodrigo","family":"de Siqueira","sequence":"additional","affiliation":[{"name":"Department of Digestive Endoscopy, Hospital S\u00edrio-Liban\u00eas, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio Carlos","family":"Conrado","sequence":"additional","affiliation":[{"name":"Endoscopy Unit, Hospital da Restaura\u00e7\u00e3o \u2013 Recife, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruno","family":"Ribeiro","sequence":"additional","affiliation":[{"name":"Endoscopy Division, UF Health Jacksonville \u2013 Jacksonville, Florida, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernando Pavinato","family":"Marson","sequence":"additional","affiliation":[{"name":"Department of Digestive Endoscopy, Hospital S\u00edrio-Liban\u00eas, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruno Gregnanin","family":"Pedron","sequence":"additional","affiliation":[{"name":"Department of Digestive Endoscopy, Hospital S\u00edrio-Liban\u00eas, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2021,6,17]]},"reference":[{"key":"ref2","doi-asserted-by":"crossref","first-page":"AB461","DOI":"10.1016\/j.gie.2013.03.408","article-title":"Endoscopic suturing procedure: what it can do and how it should be made","volume":"77","author":"K Hashiba","year":"2013","journal-title":"Gastrointest Endosc"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1111\/j.1445-2197.1990.tb07388.x","article-title":"A view of the development of intestinal suture Part II. 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