{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T09:57:40Z","timestamp":1783072660217,"version":"3.54.6"},"reference-count":74,"publisher":"Georg Thieme Verlag KG","issue":"05","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ultraschall Med"],"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This second part on Doppler sonography in prenatal medicine and obstetrics reviews its clinical applications. While this has not become the initially anticipated screening tool, it is used for the diagnosis and surveillance of a variety of fetal pathologies. For example, the sonography-based determination of uterine artery blood flow indices is an important parameter for the first trimester multimodal preeclampsia risk assessment, increasing accuracy and providing indication for the prophylactic treatment with aspirin. It also has significant implications for the diagnosis and surveillance of growth-restricted fetuses in the second and third trimesters through Doppler-sonographic analysis of umbilical artery, middle cerebral artery and ductus venosus. Here, especially the hemodynamics of the ductus venosus provides a critical criterium for birth management of severe, early-onset FGR before 34\u200a+\u200a0 weeks of gestation. Further, determination of maximum blood flow velocity of the middle cerebral artery is a central parameter in fetal diagnosis of anemia which has been significantly improved by this analysis. However, it is important to note that the mentioned improvements can only be achieved through highest methodological quality. Importantly, all these analyses are also applied to twins and higher order multiples. Here, for the differential diagnosis of specific complications such as TTTS, TAPS and TRAP, the application of Doppler sonography has become indispensable. To conclude, the successful application of Doppler sonography requires both exact methodology and precise pathophysiological interpretation of the data.<\/jats:p>","DOI":"10.1055\/a-1452-9898","type":"journal-article","created":{"date-parts":[[2021,4,27]],"date-time":"2021-04-27T22:50:27Z","timestamp":1619563827000},"page":"541-550","source":"Crossref","is-referenced-by-count":17,"title":["Doppler ultrasound in pregnancy \u2013 quality requirements of DEGUM and clinical application (part 2)"],"prefix":"10.1055","volume":"42","author":[{"given":"Renaldo","family":"Faber","sequence":"additional","affiliation":[{"name":"Leipzig, Center of Prenatal Medicine, Leipzig, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai-Sven","family":"Heling","sequence":"additional","affiliation":[{"name":"Praxis, prenetal diagnosis and human genetics, Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Horst","family":"Steiner","sequence":"additional","affiliation":[{"name":"Praxis f\u00fcr Pr\u00e4natalmedizin, Salzburg, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulrich","family":"Gembruch","sequence":"additional","affiliation":[{"name":"Obstetrics and Prenatal Medicine, University Hospital, Bonn, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2021,4,27]]},"reference":[{"key":"ref1","first-page":"319","article-title":"Dopplersonografie in der Schwangerschaft \u2013 Qualit\u00e4tsanforderungen der DEGUM und klinischer Einsatz (Teil\u00a01)","volume":"40","author":"R Faber","year":"2019","journal-title":"Ultraschall in Med"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1046\/j.1469-0705.1996.07030182.x","article-title":"Doppler ultrasound of the uterine arteries: the importance of bilateral notching in the prediction of pre-eclampsia, placental abruption or delivery of a small-for-gestational-age baby","volume":"7","author":"K Harrington","year":"1996","journal-title":"Ultrasound Obstet Gynecol"},{"key":"ref3","first-page":"559","article-title":"One-stage screening for pregnancy complications by color Doppler assessment of the uterine arteries at 23 weeks\u2019 gestation","volume":"96","author":"G Albaiges","year":"2000","journal-title":"Obstet Gynecol"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1002\/uog.15873","article-title":"Do knowledge of uterine artery resistance in the second trimester and targeted surveillance improve maternal and perinatal outcome? UTOPIA study: a randomized controlled trial","volume":"47","author":"B Garcia","year":"2016","journal-title":"Ultrasound Obstet Gynecol"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1046\/j.0960-7692.2001.00572.x","article-title":"Multicenter screening for pre-eclampsia and fetal growth restriction by transvaginal uterine artery Doppler at 23 weeks of gestation","volume":"18","author":"A Papageorghiou","year":"2001","journal-title":"Ultrasound Obstet Gynecol"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1515\/jpm.2011.077","article-title":"Screening for pre-eclampsia: a systematic review of tests combining uterine artery Doppler with other markers","volume":"39","author":"A C Pedrosa","year":"2011","journal-title":"J Perinat Med"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1097\/AOG.0b013e318242ad81","article-title":"Role of second-trimester uterine artery Doppler in assessing stillbirth risk","volume":"119","author":"T Singh","year":"2012","journal-title":"Obstet Gynecol"},{"key":"ref8","first-page":"CD008363","article-title":"Utero-placental Doppler ultrasound for improving pregnancy outcome","volume":"2010","author":"T Stampalija","year":"2010","journal-title":"Cochrane Database Syst Rev"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1097\/GRF.0b013e3181fbb65d","article-title":"Uterine Artery Doppler in First-trimester Pregnancy Screening","volume":"53","author":"R O Bahado-Singh","year":"2010","journal-title":"Clin Obstet Gynecol"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1159\/000341264","article-title":"Competing risks model in early screening for preeclampsia by biophysical and biochemical markers","volume":"33","author":"R Akolekar","year":"2013","journal-title":"Fetal Diagn Ther"},{"key":"ref11","first-page":"297","article-title":"Early Prediction of Preeclampsia","volume":"2014","author":"L C Poon","year":"2014","journal-title":"Obstet Gynecol Int"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1002\/uog.20105","article-title":"ISUOG Practice Guidelines: role of ultrasound in screening for and follow-up of pre-eclampsia","volume":"53","author":"A Sotiriadis","year":"2018","journal-title":"Ultrasound Obstet Gynecol"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1097\/AOG.0b013e3181e9322a","article-title":"Prevention of Preeclampsia and Intrauterine Growth Restriction With Aspirin Started in Early Pregnancy","volume":"116","author":"E Bujold","year":"2010","journal-title":"Obstet Gynecol"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1159\/000336662","article-title":"Early administration of low-dose aspirin for the prevention of preterm and term preeclampsia: a systematic review and meta-analysis","volume":"31","author":"S Roberge","year":"2012","journal-title":"Fetal Diagn Ther"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1056\/NEJMoa1704559","article-title":"Aspirin versus Placebo in Pregnancies at High Risk for Preterm Preeclampsia","volume":"377","author":"D L Rolnik","year":"2017","journal-title":"N Engl J Med"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1002\/uog.12366","article-title":"How to record uterine artery Doppler in the first trimester","volume":"42","author":"A Khalil","year":"2013","journal-title":"Ultrasound Obstet Gynecol"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1002\/uog.2814","article-title":"Sequential changes in uterine artery blood flow pattern between the first and second trimesters of gestation in relation to pregnancy outcome","volume":"28","author":"O Gomez","year":"2006","journal-title":"Ultrasound Obstet 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Gynecol"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1002\/pd.4412","article-title":"Stage-based approach to the management of fetal growth restriction","volume":"34","author":"F Figueras","year":"2014","journal-title":"Prenat Diagn"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"2162","DOI":"10.1016\/S0140-6736(14)62049-3","article-title":"2 year neurodevelopmental and intermediate perinatal outcomes in infants with very preterm fetal growth restriction (TRUFFLE): a randomised trial","volume":"385","author":"C C Lees","year":"2015","journal-title":"Lancet"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1055\/s-0043-118908","article-title":"Intrauterine Growth Restriction. 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Collaborative Group for Doppler Assessment of the Blood Velocity in Anemic Fetuses","volume":"342","author":"G Mari","year":"2000","journal-title":"N Engl J Med"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"526.e1","DOI":"10.1016\/j.ajog.2007.04.002","article-title":"Determinants of the middle cerebral artery peak systolic velocity in the human fetus","volume":"197","author":"A H Picklesimer","year":"2007","journal-title":"Am J Obstet Gynecol"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1002\/uog.3953","article-title":"Middle cerebral artery peak systolic velocity: a new Doppler parameter in the assessment of growth-restricted fetuses","volume":"29","author":"G Mari","year":"2007","journal-title":"Ultrasound Obstet Gynecol"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1002\/uog.3925","article-title":"First-trimester treatment of fetal anemia secondary to parvovirus B19 infection","volume":"29","author":"A Kempe","year":"2007","journal-title":"Ultrasound Obstet Gynecol"},{"key":"ref43","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1159\/000477208","article-title":"Early intrauterine transfusion in fetuses with severe anemia caused by parvovirus B19 infection","volume":"43","author":"A Hellmund","year":"2018","journal-title":"Fetal Diagn Ther"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1056\/NEJMoa052855","article-title":"DIAMOND Study Group: Doppler ultrasonography versus amniocentesis to predict fetal anemia","volume":"355","author":"D Oepkes","year":"2006","journal-title":"N Engl J Med"},{"key":"ref45","doi-asserted-by":"crossref","first-page":"1558","DOI":"10.1111\/j.1471-0528.2009.02255.x","article-title":"Noninvasive methods of detecting fetal anaemia: a systematic review and meta-analysis","volume":"116","author":"S J Pretlove","year":"2009","journal-title":"BJOG"},{"key":"ref46","doi-asserted-by":"crossref","first-page":"1340","DOI":"10.1111\/j.1471-0528.2011.03028.x","article-title":"Noninvasive fetal blood group genotyping of rhesus D, c, E and of K in alloimmunised pregnant women: evaluation of a 7-year clinical experience","volume":"118","author":"P G Scheffer","year":"2011","journal-title":"BJOG"},{"key":"ref47","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1097\/AOG.0b013e31826d7dc1","article-title":"Management and prevention of red cell alloimmunization in pregnancy: a systematic review","volume":"120","author":"K J Moise Jr","year":"2012","journal-title":"Obstet Gynecol"},{"key":"ref48","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1016\/j.ajog.2015.01.059","article-title":"Society of Maternal-Fetal Medicine (SFMF) Clinical Guideline #8: the fetus at risk for anemia \u2013 diagnosis and management","volume":"212","author":"G Mari","year":"2015","journal-title":"Am J Obstet Gynecol"},{"key":"ref49","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1067\/mob.2001.118161","article-title":"Collaborative Group for Doppler Assessment of the Blood Velocity in Anemic Fetuses: Doppler ultrasound velocimetry for timing the second intrauterine transfusion in fetuses with anemia from red cell alloimmunization","volume":"185","author":"L Detti","year":"2001","journal-title":"Am J Obstet Gynecol"},{"key":"ref50","doi-asserted-by":"crossref","first-page":"1550","DOI":"10.1016\/j.ajog.2006.03.060","article-title":"Prediction of severe fetal anemia in red blood cell alloimmunization after previous intrauterine transfusions","volume":"195","author":"M Scheier","year":"2006","journal-title":"Am J Obstet Gynecol"},{"key":"ref51","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1002\/uog.18807","article-title":"MCA Doppler Study Group. Fetal middle cerebral artery Doppler to time intrauterine transfusion in red-cell alloimmunization: a randomized trial","volume":"51","author":"J M Dodd","year":"2018","journal-title":"Ultrasound Obstet Gynecol"},{"key":"ref52","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.ejogrb.2015.06.016","article-title":"Management of severe fetal anemia by Doppler measurement of middle cerebral artery: are there other benefits than reducing invasive procedures","volume":"192","author":"C Garabedian","year":"2015","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"ref53","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1002\/pd.237","article-title":"Middle cerebral artery Doppler study in fetuses with homozygous alpha-thalassaemia-1 at 12\u201313 weeks of gestation","volume":"22","author":"Y H Lam","year":"2002","journal-title":"Prenat Diagn"},{"key":"ref54","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.bpobgyn.2011.10.009","article-title":"Thalassaemia in pregnancy","volume":"26","author":"T Y Leung","year":"2012","journal-title":"Best Pract Res Clin Obstet Gynecol"},{"key":"ref55","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1111\/j.1471-0528.2010.02749.x","article-title":"Parvovirus B19 infection in human pregnancy","volume":"118","author":"R F Lamont","year":"2011","journal-title":"BJOG"},{"key":"ref56","doi-asserted-by":"crossref","first-page":"204.e1","DOI":"10.1016\/j.ajog.2011.12.035","article-title":"Intrauterine transfusion for parvovirus B19 infection: long-term neurodevelopmental outcome","volume":"206","author":"E P de Jong","year":"2012","journal-title":"Am J Obstet Gynecol"},{"key":"ref57","doi-asserted-by":"crossref","first-page":"1290","DOI":"10.1067\/mob.2002.128024","article-title":"Noninvasive diagnosis by Doppler ultrasonography of fetal anemia resulting from parvovirus infection","volume":"187","author":"E Cosmi","year":"2002","journal-title":"Am J Obstet Gynecol"},{"issue":"S 02","key":"ref58","doi-asserted-by":"crossref","first-page":"E115","DOI":"10.1055\/s-0031-1281756","article-title":"Fetal anemia of unknown cause \u2013 a diagnostic challenge","volume":"32","author":"C Amann","year":"2011","journal-title":"Ultraschall in Med"},{"key":"ref59","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1097\/AOG.0b013e3181da7929","article-title":"Fetomaternal hemorrhage","volume":"115","author":"B J Wylie","year":"2010","journal-title":"Obstet Gynecol"},{"key":"ref60","doi-asserted-by":"crossref","first-page":"F67","DOI":"10.1136\/archdischild-2014-308004","article-title":"Prenatal therapy in transient abnormal myelopoiesis: a systematic review","volume":"101","author":"J A Tamblyn","year":"2016","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"ref61","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1002\/uog.15821","article-title":"ISUOG Practice Guidelines: role of ultrasound in twin pregnancy","volume":"47","author":"A Khalil","year":"2016","journal-title":"Ultrasound Obstet Gynecol"},{"key":"ref62","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1046\/j.1469-0705.2002.00866.x","article-title":"Doppler assessment of the uterine circulation in the second trimester in twin pregnancies: prediction of pre-eclampsia, fetal growth restriction and birth weight discordance","volume":"20","author":"A Geipel","year":"2002","journal-title":"Ultrasound Obstet Gynecol"},{"key":"ref63","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/j.placenta.2009.02.005","article-title":"The basic and clinical science of twin-twin transfusion syndrome","volume":"30","author":"N M Fisk","year":"2009","journal-title":"Placenta"},{"key":"ref64","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1038\/sj.jp.7200292","article-title":"Staging of twin-twin transfusion syndrome","volume":"19","author":"R A Quintero","year":"1999","journal-title":"J Perinatol"},{"key":"ref65","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1056\/NEJMoa032597","article-title":"Endoscopic laser surgery versus serial amnioreduction for severe twin-to-twin transfusion syndrome","volume":"351","author":"M V Senat","year":"2004","journal-title":"N\u00a0Engl J Med"},{"key":"ref66","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1159\/000304512","article-title":"Twin anemia-polycythemia sequence: diagnostic criteria, classification, perinatal management and outcome","volume":"27","author":"F Slaghekke","year":"2010","journal-title":"Fetal Diagn Ther"},{"key":"ref67","doi-asserted-by":"crossref","first-page":"285.e1\u2013e7","DOI":"10.1016\/j.ajog.2014.05.012","article-title":"Residual anastomoses in twin-twin transfusion syndrome after laser: the Solomon randomized trial","volume":"211","author":"F Slaghekke","year":"2014","journal-title":"Am J Obstet Gynecol"},{"key":"ref68","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1159\/000365919","article-title":"Pre-operative twin anemia\/polycythemia in the setting of twin-twin transfusion syndrome (TTTS)","volume":"37","author":"K R van Winden","year":"2015","journal-title":"Fetal Diagn Ther"},{"key":"ref69","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1002\/uog.14925","article-title":"Middle cerebral artery peak systolic velocity to predict fetal hemoglobin levels in twin anemia-polycythemia sequence","volume":"46","author":"F Slaghekke","year":"2015","journal-title":"Ultrasound Obstet Gynecol"},{"key":"ref70","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1002\/uog.20096","article-title":"Improved antenatal prediction of twin anemia-polycythemia sequence by delta middle cerebral artery peak systolic velocity: a new antenatal classification system","volume":"53","author":"L SA Tollenaar","year":"2019","journal-title":"Ultrasound Obstet Gynecol"},{"key":"ref71","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1002\/uog.20116","article-title":"Role of fetal intertwin difference in middle cerebral artery peak systolic velocity in predicting neonatal twin anemia-polycythemia sequence","volume":"53","author":"M Tavares de Sousa","year":"2019","journal-title":"Ultrasound Obstet Gynecol"},{"key":"ref72","doi-asserted-by":"crossref","first-page":"213.e1\u20134","DOI":"10.1016\/j.ajog.2010.04.018","article-title":"The outcome of twin reversed arterial perfusion sequence diagnosed in the first trimester","volume":"203","author":"L 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