{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,4,29]],"date-time":"2024-04-29T13:56:16Z","timestamp":1714398976061},"reference-count":33,"publisher":"Georg Thieme Verlag KG","issue":"05","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Fortschr Neurol Psychiatr"],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>St\u00f6rungen des Gehens, der Mobilit\u00e4t und St\u00fcrze sind h\u00e4ufige Gesundheitsprobleme von Patienten mit chronischen, neurologischen Erkrankungen. Daher ist es wichtig, neben der Behandlung der neurologischen Grunderkrankung auch symptomatische Therapieoptionen mit dem Ziel der Verbesserung des Gehens einzusetzen.<\/jats:p><jats:p>Mittels einer selektiven Literaturrecherche von Studien mit expliziter Untersuchung der Gehf\u00e4higkeit wurden symptomatische Therapiem\u00f6glichkeiten in den folgenden klinischen Entscheidungsfeldern identifiziert und diskutiert: (1) hypokinetische Gangst\u00f6rung (z.B. bei M. Parkinson, Normaldruckhydrocephalus und vaskul\u00e4rer Enzephalopathie), (2) Gangunsicherheit mit Ataxie (sensorisch und zerebell\u00e4r) und (3) spastisch-paretische Gangst\u00f6rung (bei Multipler Sklerose). Es werden medikament\u00f6se und nicht-medikament\u00f6se Therapieoptionen analysiert, speziell zu den Funktionsbereichen \u201eLokomotion\u201c, \u201eposturale Kontrolle\u201c, \u201eModulation\u201c und \u201eAdaptionsf\u00e4higkeit\u201c. Die medikament\u00f6sen Behandlungskonzepte orientieren sich vorwiegend an den pathophysiologischen Ver\u00e4nderungen der Grunderkrankungen. Physikalisch-medizinische Basistherapien sowie Gang- und Bewegungstherapien erweitern das therapeutische Spektrum. Zudem k\u00f6nnen geh-relevante Einzelsymptome effizient mittels physikalisch-medizinischer oder pharmakologischer Therapien verbessert werden.<\/jats:p><jats:p>Die Behandlungsoptionen neurologischer Gangst\u00f6rungen sind gut und systematisch untersucht und erm\u00f6glichen eine individuelle Anpassung an die zugrundeliegende neurologische Erkrankung, an die Funktionsdefizite der individuellen Gangst\u00f6rung sowie an relevante Einzelsymptome, welche das Gehen nochmals verschlechtern.<\/jats:p>","DOI":"10.1055\/a-1472-5860","type":"journal-article","created":{"date-parts":[[2021,4,24]],"date-time":"2021-04-24T01:16:12Z","timestamp":1619226972000},"page":"243-253","source":"Crossref","is-referenced-by-count":3,"title":["Symptomatische Behandlungsoptionen chronischer, neurologischer Gangst\u00f6rungen"],"prefix":"10.1055","volume":"89","author":[{"given":"Roman","family":"Schniepp","sequence":"additional","affiliation":[{"name":"Deutsches Schwindel- und Gleichgewichtszentrum, Ludwig-Maximilians Universit\u00e4t M\u00fcnchen"},{"name":"Neurologische Klinik, Ludwig-Maximilians Universit\u00e4t M\u00fcnchen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ken","family":"M\u00f6hwald","sequence":"additional","affiliation":[{"name":"Deutsches Schwindel- und Gleichgewichtszentrum, Ludwig-Maximilians Universit\u00e4t M\u00fcnchen"},{"name":"Neurologische Klinik, Ludwig-Maximilians Universit\u00e4t M\u00fcnchen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Max","family":"Wuehr","sequence":"additional","affiliation":[{"name":"Deutsches Schwindel- und Gleichgewichtszentrum, Ludwig-Maximilians Universit\u00e4t M\u00fcnchen"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2021,4,23]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1002\/mds.20266","article-title":"Prevalence of gait disorders in hospitalized neurological 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