{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,6]],"date-time":"2022-04-06T01:44:56Z","timestamp":1649209496208},"reference-count":28,"publisher":"Georg Thieme Verlag KG","issue":"04","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nuklearmedizin"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>\n          Ziel\u2002Lokalrezidive von Schilddr\u00fcsenkarzinomen k\u00f6nnen zu einer Tumorinfiltration im unteren Kehlkopfbereich f\u00fchren. Da diese Tumoren in der Regel nicht mehr jodspeichernd sind, sind die weiteren Therapieoptionen erheblich eingeschr\u00e4nkt. Die vorliegende Arbeit beschreibt unsere Erfahrung mit laryngotrachealen Resektionen dieser Lokalrezidive.<\/jats:p><jats:p>\n          Material und Methode\u2002Von Juli 2019 bis November 2020 behandelten wir 5 Patienten mit maligner Infiltration der Trachea und des Larynx durch ein Lokalrezidiv eines Schilddr\u00fcsenkarzinoms. Wir f\u00fchrten bei 4 Patienten eine laryngotracheale Resektion mit End-zu-End-Anastomose durch, bei einer Patientin erfolgte eine frontolaterale Teillaryngektomie.<\/jats:p><jats:p>\n          Ergebnisse\u2002Der Krankenhausaufenthalt betrug median 6\u00a0Tage (5\u201314). Eine R0-Resektion wurde nur bei 2 Patienten erreicht. Bei keinem Patienten traten Probleme mit der Anastomose oder eine beidseitige Rekurrensparese auf. Ein Patient musste am ersten postoperativen Tag wegen zunehmenden Lungenversagens reintubiert werden. Er konnte nach 5 Tagen extubiert werden.<\/jats:p><jats:p>\n          Schlussfolgerung\u2002Hohe Trachealresektionen mit Teilresektion des Larynx k\u00f6nnen mit geringem Risiko durchgef\u00fchrt werden. Obwohl onkologisch radikale Resektionen selten sind, stellen diese Resektionen eine Erweiterung der Therapieoptionen bei jodrefrakt\u00e4ren Lokalrezidiven von Schilddr\u00fcsenkarzinomen dar. Hohe Trachealresektionen k\u00f6nnten Teil des onkologischen Therapiespektrums beim lokal rezidivierenden, nicht mehr Jod speichernden Schilddr\u00fcsenkarzinom werden.<\/jats:p>","DOI":"10.1055\/a-1475-3638","type":"journal-article","created":{"date-parts":[[2021,5,25]],"date-time":"2021-05-25T23:01:10Z","timestamp":1621983670000},"page":"272-277","source":"Crossref","is-referenced-by-count":0,"title":["Lokalrezidive von jodrefrakt\u00e4ren Schilddr\u00fcsenkarzinomen \u2013 chirurgische Therapieoption bei Infiltration des Kehlkopfs"],"prefix":"10.1055","volume":"60","author":[{"given":"Heinrich","family":"Fuerst","sequence":"additional","affiliation":[{"name":"Chirurgische Klinik, Krankenhaus Martha-Maria, M\u00fcnchen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Negele","sequence":"additional","affiliation":[{"name":"Chirurgische Klinik, Krankenhaus Martha-Maria, M\u00fcnchen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nikolaos","family":"Tsalos","sequence":"additional","affiliation":[{"name":"Chirurgische Klinik, Krankenhaus Martha-Maria, M\u00fcnchen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"Fertl","sequence":"additional","affiliation":[{"name":"Zentrum f\u00fcr Innere Medizin, Krankenhaus Martha-Maria, M\u00fcnchen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Markus","family":"Suckf\u00fcll","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Hals-, Nasen- und Ohrenheilkunde, Krankenhaus Martha-Maria, M\u00fcnchen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrei","family":"Todica","sequence":"additional","affiliation":[{"name":"Klinik und Poliklinik f\u00fcr Nuklearmedizin, Klinikum Gro\u00dfhadern, M\u00fcnchen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Bartenstein","sequence":"additional","affiliation":[{"name":"Klinik und Poliklinik f\u00fcr Nuklearmedizin, Klinikum Gro\u00dfhadern, M\u00fcnchen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2021,5,25]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"2370","DOI":"10.1200\/JCO.2014.59.8391","article-title":"Presence and number of lymph node metastases are associated with compromised survival for patients younger than age 45 years with papillary thyroid cancer","volume":"33","author":"M A Adam","year":"2015","journal-title":"J Clin Oncol"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"497","DOI":"10.1016\/j.ecl.2008.02.001","article-title":"External beam radiation therapy for thyroid cancer","volume":"37","author":"J D Brierley","year":"2008","journal-title":"Endocrinol Metabol Clinics North 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