{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T08:32:49Z","timestamp":1740126769498,"version":"3.37.3"},"reference-count":24,"publisher":"Georg Thieme Verlag KG","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Laryngorhinootologie"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>\n          Einleitung\u2002Die Zahl der Schilddr\u00fcsenmalignome zeigt eine deutliche Zunahme. Da die Schilddr\u00fcse an der HNO-Klinik Bad Hersfeld im Fokus steht, war dies f\u00fcr uns Anlass, unsere Behandlungsresultate zu untersuchen und Erfahrungen darzustellen.<\/jats:p><jats:p>\n          Material und Methoden\u2002Es handelt sich um eine Untersuchung beginnend im Jahre 2014 bis zum Juli 2020. Es wurden alle Patienten mit Schilddr\u00fcsenmalignomen erfasst und wichtige demografische und medizinische Parameter wie Alter, Geschlecht, Histologie, Calcium, OP-Dauer, Rekurrensparese etc. registriert.<\/jats:p><jats:p>\n          Ergebnisse\u2002Es wurden insgesamt 63 Patienten mit malignen Schilddr\u00fcsenerkrankungen eingeschlossen. Davon waren 42\u00a0weiblichen und 21 m\u00e4nnlichen Geschlechts. Die Altersspanne reichte von 11 bis zu 95 Jahren. Patienten mit differenzierten Schilddr\u00fcsenkarzinomen waren im Schnitt j\u00fcnger als diejenigen mit anaplastischen Malignomen. Histologisch dominierten die papill\u00e4ren Schilddr\u00fcsenkarzinome mit 65\u200a% (n\u200a=\u200a41) gegen\u00fcber anderen Varianten wie dem follikul\u00e4ren (n\u200a=\u200a6), medull\u00e4ren (n\u200a=\u200a5) und entdifferenzierten Karzinom (n\u200a=\u200a6). Alle Patienten wurden einer operativen Behandlung unterzogen; postoperativ erhielten die Betroffenen mit fortgeschrittenen, differenzierten Karzinomen eine Radiojodtherapie. Von den Patienten mit einem entdifferenzierten Karzinom sind alle ihrem Leiden erlegen, w\u00e4hrend nach unserer Kenntnis nur eine Betroffene mit einem differenzierten Malignom tumorbedingt verstorben ist.<\/jats:p><jats:p>\n          Schlussfolgerung\u2002In die Behandlung von malignen Schilddr\u00fcsenerkrankungen ist der HNO-Arzt eingebunden. Wie bei den benignen Erkrankungen der endokrinen Halsorgane ist eine interdisziplin\u00e4re Zusammenarbeit entscheidend.<\/jats:p>","DOI":"10.1055\/a-1475-4939","type":"journal-article","created":{"date-parts":[[2021,4,27]],"date-time":"2021-04-27T22:48:48Z","timestamp":1619563728000},"page":"889-895","source":"Crossref","is-referenced-by-count":0,"title":["Die Behandlung von Schilddr\u00fcsenmalignomen aus HNO-\u00e4rztlicher Sicht"],"prefix":"10.1055","volume":"100","author":[{"given":"Peter Rolf","family":"Issing","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Hals-Nasen-Ohrenheilkunde, Klinikum Bad Hersfeld GmbH, Bad Hersfeld, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Torsten","family":"K\u00f6hler","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Hals-Nasen-Ohrenheilkunde, Klinikum Bad Hersfeld GmbH, Bad Hersfeld, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hendrik","family":"Tebben","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Hals-Nasen-Ohrenheilkunde, Klinikum Bad Hersfeld GmbH, Bad Hersfeld, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Wenger","sequence":"additional","affiliation":[{"name":"Nuklearmedizin, Klinikum Bad Hersfeld GmbH, Bad\u00a0Hersfeld, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9433-8306","authenticated-orcid":false,"given":"Christian","family":"Issing","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Hals-Nasen-Ohrenheilkunde, Universit\u00e4tsklinikum Frankfurt, Frankfurt am Main, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2021,4,27]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1002\/hed.23848","article-title":"High prevalence of papillary thyroid cancer in Korean women with insulin resistance","volume":"38","author":"M J Bae","year":"2016","journal-title":"Head & Neck"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1089\/thy.2013.0045","article-title":"The increasing incidence of thyroid cancer: The influence of access to care","volume":"23","author":"L GT Morris","year":"2013","journal-title":"Thyroid"},{"key":"ref4","volume-title":"TNM-Klassifikation maligner Tumoren","author":"C Wittekind","year":"2017","edition":"8 Aufl."},{"key":"ref5","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1055\/s-0042-119071","article-title":"Prospektive Untersuchung zur Ergebnisqualit\u00e4t von Schilddr\u00fcsenoperationen in einer HNO-Klinik","volume":"96","author":"P R Issing","year":"2017","journal-title":"Laryngo Rhino Otol"},{"key":"ref6","volume-title":"Diagnostik und Therapie von Schilddr\u00fcsenerkrankungen","author":"F Gr\u00fcnwald","year":"2019","edition":"2. 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