{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T21:58:50Z","timestamp":1781906330048,"version":"3.54.5"},"reference-count":32,"publisher":"Georg Thieme Verlag KG","issue":"08","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Klin Monbl Augenheilkd"],"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background There are various imaging techniques for the assessment of the optic disc in glaucoma patients. However, anatomically conspicuous, large or small optic discs can be quite\n\t\t\t\t\tchallenging for an examiner.<\/jats:p><jats:p>\n          Objective The Bruch\u02bcs membrane opening (BMO) by spectral domain optical coherence tomography (SD-OCT) is a modern approach for the quantitative measures of retinal nerve fibre layer\n\t\t\t\t\t(RNFL). The study focuses on comparison analysis of the BMO method and the widely used Heidelberg retina tomograph (HRT) method \u2013 in terms of detection of glaucoma for different optic disc\n\t\t\t\t\tsizes.<\/jats:p><jats:p>\n          Methods 216 Patients examinations during glaucoma consultation hours. Macro- (Ma) and micro-optic discs (Mi) detected by HRT are analysed via BMO analysis in SD-OCT. Correlation\n\t\t\t\t\tbetween BMO area and optic disc measured by HRT has been investigated and examined in terms of severity of visual field defect (MD [dB]).<\/jats:p><jats:p>\n          Results The results of study show that for micro and macro-optic discs there is a modest correlation between the size of optic disc measured by BMO and the size of optic disc\n\t\t\t\t\tmeasured by HRT by applying funduscopic examination (correlation rate r\u2009=\u20090,53; Mi: n\u2009=\u2009111, Ma: n\u2009=\u2009105). For micro-optic discs with a very small BMO area (&lt;\u20091.5\u2009mm2), there\n\t\t\t\t\tis a significant tendency (linear trend test p\u2009&lt;\u20090.05) towards deeper visual field defects (MD &lt; \u2212\u20095\u2009dB).<\/jats:p><jats:p>\n          Conclusion The BMO parameter of SD-OCT allows an assessment of glaucoma for a large range of optic disc sizes. BMO area and optic disc size measured by HRT are not correlated. Micro\n\t\t\t\t\toptic discs with a small BMO area lead to a higher risk of deep visual field defects.<\/jats:p>","DOI":"10.1055\/a-1478-3978","type":"journal-article","created":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T23:00:55Z","timestamp":1625180455000},"page":"1043-1051","source":"Crossref","is-referenced-by-count":5,"title":["Glaucoma Diagnostic Testing: The Influence of Optic Disc Size"],"prefix":"10.1055","volume":"239","author":[{"given":"Pascal","family":"Scheuble","sequence":"additional","affiliation":[{"name":"Sektion Glaukom, Universit\u00e4ts-Augenklinik Bonn, Universit\u00e4tsklinikum Bonn, Deutschland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Petrak","sequence":"additional","affiliation":[{"name":"Sektion Glaukom, Universit\u00e4ts-Augenklinik Bonn, Universit\u00e4tsklinikum Bonn, Deutschland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian Karl","family":"Brinkmann","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Augenheilkunde, Dietrich Bonhoeffer Klinikum Neubrandenburg, Deutschland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2021,7,1]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"1011","DOI":"10.1001\/archopht.1984.01040030813022","article-title":"Neuroretinal rim area in suspected glaucoma and early chronic open-angle glaucoma: Correlation with parameters of visual function","volume":"102","author":"A Balazsi","year":"1984","journal-title":"Arch Ophthal"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1007\/s10792-006-9022-9","article-title":"Interobserver variability in confocal optic nerve analysis (HRT)","volume":"26","author":"M M Hermann","year":"2005","journal-title":"Int 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Garway-Heath","year":"2000","journal-title":"Ophthalmology"}],"container-title":["Klinische Monatsbl\u00e4tter f\u00fcr Augenheilkunde"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-1478-3978.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,17]],"date-time":"2022-08-17T01:59:14Z","timestamp":1660701554000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-1478-3978"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7,1]]},"references-count":32,"journal-issue":{"issue":"08","published-online":{"date-parts":[[2022,8,16]]},"published-print":{"date-parts":[[2022,8]]}},"URL":"https:\/\/doi.org\/10.1055\/a-1478-3978","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0023-2165","1439-3999"],"issn-type":[{"value":"0023-2165","type":"print"},{"value":"1439-3999","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,7,1]]}}}