{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,19]],"date-time":"2025-04-19T18:01:33Z","timestamp":1745085693456},"reference-count":24,"publisher":"Georg Thieme Verlag KG","issue":"06","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pneumologie"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>In der Corona-Pandemie werden zunehmend nicht-invasive Verfahren zur Behandlung des akuten hypox\u00e4mischen Versagens bei COVID-19 eingesetzt. Hier stehen mit der HFOT (high-flow oxygen therapy), CPAP (continuous positive airway pressure) und der NIV (non-invasive ventilation) unterschiedliche Verfahren zur Verf\u00fcgung, die das Ziel einer Intubationsvermeidung verfolgen. Der aktuelle \u00dcbersichtsartikel fasst die heterogene Studienlage zusammen. Wesentlich ist die Erkenntnis, dass diese nicht-invasiven Verfahren durchaus auch bei einem schweren, akuten hypox\u00e4mischen Versagen erfolgreich sein k\u00f6nnen und damit die Intubation wie auch Tubus-assoziierte Komplikationen vermeiden k\u00f6nnen. Demgegen\u00fcber bleibt aber ebenso zu betonen, dass die prolongierte unterst\u00fctzte Spontanatmung ebenfalls zu Komplikationen f\u00fchrt und dass demzufolge insbesondere ein sp\u00e4tes NIV-Versagen mit erheblich verschlechterter Prognose einhergeht, was vor dem Hintergrund weiterhin hoher NIV-Versagensraten in Deutschland bedeutsam ist. Der aktuelle Artikel verweist schlie\u00dflich auch auf einen Parallelartikel in dieser Ausgabe, der die medial in der \u00d6ffentlichkeit in Deutschland gef\u00fchrte Debatte zu diesem Thema aufgreift und deren inhaltliche Fragw\u00fcrdigkeit, aber auch die negativen Auswirkungen auf die Gesellschaft und die Fachwelt adressiert. Gleichzeitig wird die Bedeutung von regelm\u00e4\u00dfig zu \u00fcberarbeitenden Leitlinien untermauert.<\/jats:p>","DOI":"10.1055\/a-1486-1015","type":"journal-article","created":{"date-parts":[[2021,5,11]],"date-time":"2021-05-11T23:03:30Z","timestamp":1620774210000},"page":"424-431","source":"Crossref","is-referenced-by-count":6,"title":["Bedeutung nicht-invasiver Verfahren in der Therapie des akuten hypox\u00e4mischen Versagens bei COVID-19"],"prefix":"10.1055","volume":"75","author":[{"given":"Wolfram","family":"Windisch","sequence":"additional","affiliation":[{"name":"Lungenklinik Merheim, Kliniken der Stadt K\u00f6ln gGmbH"},{"name":"Universit\u00e4t Witten\/Herdecke"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernd","family":"Sch\u00f6nhofer","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Innere Medizin, Pneumologie und Intensivmedizin; Evangelisches Klinikum Bethel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel Sebastian","family":"Majorski","sequence":"additional","affiliation":[{"name":"Lungenklinik Merheim, Kliniken der Stadt K\u00f6ln gGmbH"},{"name":"Universit\u00e4t Witten\/Herdecke"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maximilian","family":"Wollsching-Strobel","sequence":"additional","affiliation":[{"name":"Lungenklinik Merheim, Kliniken der Stadt K\u00f6ln gGmbH"},{"name":"Universit\u00e4t Witten\/Herdecke"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carl-Peter","family":"Cri\u00e9e","sequence":"additional","affiliation":[{"name":"Evangelisches Krankenhaus G\u00f6ttingen Weende, Abteilung f\u00fcr Pneumologie, Bovenden-Lenglern"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah Bettina","family":"Schwarz","sequence":"additional","affiliation":[{"name":"Lungenklinik Merheim, Kliniken der Stadt K\u00f6ln gGmbH"},{"name":"Universit\u00e4t Witten\/Herdecke"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Westhoff","sequence":"additional","affiliation":[{"name":"Universit\u00e4t Witten\/Herdecke"},{"name":"Lungenklinik Hemer, Zentrum f\u00fcr Pneumologie und Thoraxchirurgie, Hemer"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2021,5,11]]},"reference":[{"key":"ref1","first-page":"528","article-title":"Invasive and Non-Invasive Ventilation in Patients With COVID-19","volume":"117","author":"W Windisch","year":"2020","journal-title":"Dtsch Arztebl Int"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1055\/a-1321-3400","article-title":"Risikoabsch\u00e4tzung bei Patienten mit chronischen Atemwegs- und Lungenerkrankungen im Rahmen der SARS-CoV-2-Pandemie","volume":"75","author":"M Lommatzsch","year":"2021","journal-title":"Pneumologie"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1055\/a-1157-9976","article-title":"Positionspapier zur praktischen Umsetzung der apparativen Differenzialtherapie der akuten respiratorischen Insuffizienz bei COVID-19. 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