{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T13:16:58Z","timestamp":1791811018290,"version":"4.3.4"},"reference-count":12,"publisher":"Georg Thieme Verlag KG","issue":"04","funder":[{"name":"Henan province innovation talents of science and technology plan","award":["184200510020"],"award-info":[{"award-number":["184200510020"]}]},{"DOI":"10.13039\/501100001809","name":"Natural science foundation of China","doi-asserted-by":"crossref","award":["818704540"],"award-info":[{"award-number":["818704540"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Endoscopy"],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background\u2002This study aimed to investigate the diagnostic and therapeutic value of a digital single-operator cholangioscope (SOC) system for endoscopic management of acute appendicitis.<\/jats:p><jats:p>\n          Methods\u200214 patients with acute uncomplicated simple or supportive appendicitis were evaluated between November 2018 and September 2020. The diagnosis of acute appendicitis was confirmed by direct colonoscopy imaging and cholangioscope. The success rate of digital SOC-assisted endoscopic retrograde appendicitis therapy (ERAT), the procedure time, postoperative length of hospital stay, complications, and recurrence rate were recorded.<\/jats:p><jats:p>\n          Results\u2002Technical success rate was 100\u200a%, with high quality imaging of the appendiceal cavity achieved using SOC in all 14 patients. The mean procedure time was 37.8 (standard deviation [SD] 22) minutes. All patients experienced immediate relief from abdominal pain after the procedure. Mean postoperative hospitalization was 1.9 (SD 0.7) days. No recurrence occurred during 2\u201324 months of follow-up.<\/jats:p><jats:p>\n          Conclusion\u2002Digital SOC-assisted ERAT provided a feasible, safe, and effective alternative approach for diagnosis and management of acute uncomplicated appendicitis without the need for X-ray or ultrasonic guidance.<\/jats:p>","DOI":"10.1055\/a-1490-0434","type":"journal-article","created":{"date-parts":[[2021,4,24]],"date-time":"2021-04-24T01:22:08Z","timestamp":1619227328000},"page":"396-400","source":"Crossref","is-referenced-by-count":54,"title":["Digital single-operator cholangioscope for endoscopic retrograde appendicitis therapy"],"prefix":"10.1055","volume":"54","author":[{"given":"Ling-Jian","family":"Kong","sequence":"first","affiliation":[{"name":"Department of Gastroenterology and Hepatology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Gastroenterology and Hepatology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji-Yu","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saif","family":"Ullah","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lixia","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deliang","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huiyu","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bing-Rong","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2021,6,17]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1016\/j.gie.2012.05.029","article-title":"Endoscopic retrograde appendicitis therapy: a pilot minimally invasive technique (with videos)","volume":"76","author":"B R Liu","year":"2012","journal-title":"Gastrointest Endosc"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1055\/a-0581-9119","article-title":"Endoscopic retrograde appendicitis techniques for the treatment of patients with acute appendicitis","volume":"56","author":"L P Ye","year":"2018","journal-title":"Z Gastroenterol"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1007\/s00464-014-3750-0","article-title":"Endoscopic retrograde appendicitis therapy (ERAT): a multicenter retrospective study in China","volume":"29","author":"B R Liu","year":"2015","journal-title":"Surg Endosc"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"3285","DOI":"10.1007\/s10620-016-4245-8","article-title":"Diagnosis of acute appendicitis by endoscopic retrograde appendicitis therapy (ERAT): combination of colonoscopy and endoscopic retrograde appendicography","volume":"61","author":"Y Li","year":"2016","journal-title":"Dig Dis Sci"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1016\/j.ajem.2014.10.004","article-title":"Diagnosis of appendicitis by bedside ultrasound in the ED","volume":"33","author":"M Mallin","year":"2015","journal-title":"Am J Emerg Med"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"1278","DOI":"10.1016\/S0140-6736(15)00275-5","article-title":"Acute appendicitis: modern understanding of pathogenesis, diagnosis, and management","volume":"386","author":"A Bhangu","year":"2015","journal-title":"Lancet"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/j.amjsurg.2010.10.009","article-title":"Negative appendectomy: a 10-year review of a nationally representative sample","volume":"201","author":"S A Seetagal","year":"2011","journal-title":"Am J Surg"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1080\/08941939.2018.1453566","article-title":"Negative appendectomy. It is really preventable?","volume":"32","author":"P C Ambe","year":"2019","journal-title":"J Invest Surg"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"1794","DOI":"10.1016\/j.jpedsurg.2018.10.106","article-title":"The impact of pathological criteria on pediatric negative appendectomy rate","volume":"54","author":"C Maloney","year":"2019","journal-title":"J Pediatr Surg"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1016\/j.amjsurg.2016.05.020","article-title":"Predictive factors and outcomes of negative appendectomy","volume":"213","author":"B G Jeon","year":"2017","journal-title":"Am J Surg"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-020-08129-8","article-title":"The modified endoscopic retrograde appendicitis therapy versus antibiotic therapy alone for acute uncomplicated appendicitis in children","author":"J Kang","year":"2020","journal-title":"Surg Endosc"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"1649","DOI":"10.1007\/s00384-017-2878-5","article-title":"A prospective non-randomized controlled, multicenter trial comparing Appendectomy and Conservative Treatment for Patients with Uncomplicated Acute Appendicitis (the ACTUAA study)","volume":"32","author":"M Podda","year":"2017","journal-title":"Int J Colorectal Dis"}],"container-title":["Endoscopy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-1490-0434.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,10]],"date-time":"2022-08-10T09:53:55Z","timestamp":1660125235000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-1490-0434"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4,23]]},"references-count":12,"journal-issue":{"issue":"04","published-online":{"date-parts":[[2022,3,29]]},"published-print":{"date-parts":[[2022,4]]}},"URL":"https:\/\/doi.org\/10.1055\/a-1490-0434","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0013-726X","1438-8812"],"issn-type":[{"value":"0013-726X","type":"print"},{"value":"1438-8812","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2021,4,23]]},"published":{"date-parts":[[2021,4,23]]}}}