{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T21:58:35Z","timestamp":1782424715546,"version":"3.54.5"},"reference-count":38,"publisher":"Georg Thieme Verlag KG","issue":"08","license":[{"start":{"date-parts":[[2021,5,4]],"date-time":"2021-05-04T00:00:00Z","timestamp":1620086400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Thromb Haemost"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Historically, the vaccination strategies developed in the second half of the 20th century have facilitated the eradication of infectious diseases. From the onset of COVID-19 pandemic to the end of April 2021, more than 150 million cases and 3 million deaths were documented worldwide with disruption of the economic and social activity, and with devastating material, physical, and psychological consequences. Reports of unusual and severe thrombotic events, including cerebral and splanchnic venous thrombosis and other autoimmune adverse reactions, such as immune thrombocytopenia or thrombotic microangiopathies in connection with some of the SARS-CoV-2 vaccines, have caused a great deal of concern within the population and the medical community. This report is intended to provide practical answers following an overview of our knowledge on these thrombotic events that are extremely rare but have serious consequences. Vaccine hesitancy threatens to reverse the progress made in controlling vaccine-preventable diseases. These adverse events must be put into perspective with an objective analysis of the facts and the issues of the vaccination strategy during this SARS-CoV-2 pandemic. Health care professionals remain the most pertinent advisors and influencers regarding vaccination decisions; they have to be supported to provide reliable and credible information on vaccines. We need to inform, reassure, and support our patients when the prescription is made. Facing these challenges and observations, a panel of experts express their insights and propose a tracking algorithm for vaccinated patients based on a 10-point guideline for decision-making on what to do and not to do.<\/jats:p>","DOI":"10.1055\/a-1499-0119","type":"journal-article","created":{"date-parts":[[2021,5,4]],"date-time":"2021-05-04T22:55:35Z","timestamp":1620168935000},"page":"982-991","source":"Crossref","is-referenced-by-count":52,"title":["SARS-CoV-2 Vaccine and Thrombosis: An Expert Consensus on Vaccine-Induced Immune Thrombotic Thrombocytopenia"],"prefix":"10.1055","volume":"121","author":[{"given":"Ismail","family":"Elalamy","sequence":"additional","affiliation":[{"name":"Hematology and Thrombosis Center, H\u00f4pital Tenon, H\u00f4pitaux Universitaires de l'Est Parisien, Assistance Publique H\u00f4pitaux de Paris, Facult\u00e9 de M\u00e9decine, Sorbonne Universit\u00e9, Paris, France"},{"name":"Research Group \u201cCancer, Haemostasis and Angiogenesis,\u201d INSERM U938, Centre de Recherche Saint-Antoine, Institut Universitaire de Canc\u00e9rologie, Faculty of Medicine, Sorbonne University, Paris, France"},{"name":"Department of Obstetrics and Gynaecology, The First I.M. Sechenov Moscow State Medical University, Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2316-6348","authenticated-orcid":false,"given":"Grigoris","family":"Gerotziafas","sequence":"additional","affiliation":[{"name":"Hematology and Thrombosis Center, H\u00f4pital Tenon, H\u00f4pitaux Universitaires de l'Est Parisien, Assistance Publique H\u00f4pitaux de Paris, Facult\u00e9 de M\u00e9decine, Sorbonne Universit\u00e9, Paris, France"},{"name":"Research Group \u201cCancer, Haemostasis and Angiogenesis,\u201d INSERM U938, Centre de Recherche Saint-Antoine, Institut Universitaire de Canc\u00e9rologie, Faculty of Medicine, Sorbonne University, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonia","family":"Alamowitch","sequence":"additional","affiliation":[{"name":"AP-HP, Service des Urgences c\u00e9r\u00e9bro-vasculaires, H\u00f4pital Piti\u00e9-Salp\u00e9tri\u00e8re, Paris, France"},{"name":"Centre de recherche de Saint Antoine, INSERM, UMRS 938, Sorbonne Universit\u00e9 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Pierre","family":"Laroche","sequence":"additional","affiliation":[{"name":"Service de m\u00e9decine vasculaire, h\u00f4pital Saint-\u00c9loi, CHU de Montpellier, Montpellier cedex 5, France"},{"name":"M\u00e9dip\u00f4le, 1139, chemin du Lavarin, Avignon, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Van Dreden","sequence":"additional","affiliation":[{"name":"Research Group \u201cCancer, Haemostasis and Angiogenesis,\u201d INSERM U938, Centre de Recherche Saint-Antoine, Institut Universitaire de Canc\u00e9rologie, Faculty of Medicine, Sorbonne University, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Walter","family":"Ageno","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine and Thrombosis Center, Ospedale di Circolo and Department of Medicine and Surgery, University of Insubria, Varese, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Beyer-Westendorf","sequence":"additional","affiliation":[{"name":"Department of Medicine I, Division of Haematology and Haemostaseology, University Hospital Carl Gustav Carus, Technische Universit\u00e4t Dresden, Dresden, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander T.","family":"Cohen","sequence":"additional","affiliation":[{"name":"Department of Haematological Medicine, Guys and St Thomas' NHS Foundation Trust, King's College London, London, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Jimenez","sequence":"additional","affiliation":[{"name":"Respiratory Department, Ramon y Cajal Hospital (IRYCIS), CIBER Enfermedades Respiratorias (CIBERES), Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin","family":"Brenner","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, The First I.M. 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