{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T08:34:42Z","timestamp":1740126882552,"version":"3.37.3"},"reference-count":16,"publisher":"Georg Thieme Verlag KG","issue":"04","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Z Geburtshilfe Neonatol"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Obwohl sich fast 40% aller Todesf\u00e4lle im Kindes- und Jugendalter\n                    w\u00e4hrend der Neugeborenenperiode ereignen, kommt es in der Neonatologie\n                    nur selten zur Organspende. Wir berichten \u00fcber ein Neugeborenes, bei dem\n                    nach perinataler Asphyxie der endg\u00fcltige, nicht behebbare Ausfall der\n                    Gesamtfunktion des Gro\u00dfhirns, des Kleinhirns und des Hirnstamms\n                    (\u201eHirntod\u201c) gem\u00e4\u00df Transplantationsgesetz\n                    diagnostiziert wurde. Das Herz wurde nach der sogenannten zweiten\n                    richtliniengem\u00e4\u00dfen \u201eHirntoddiagnostik\u201c zur\n                    Organspende entnommen und erfolgreich transplantiert. Besondere juristische\n                    Herausforderungen ergaben sich aus dem Umstand der anonymen Geburt, den\n                    notwendigen Regelungen der Vormundschaft sowie der Zuordnung des\n                    Totenf\u00fcrsorgerechts. Medizinisch standen die speziellen Regelungen der\n                    Diagnostik des irreversiblen Hirnfunktionsausfalls bei Neugeborenen und der\n                    optimale Erhalt der Organfunktion vor Entnahme im Vordergrund. F\u00fcr die\n                    Pflegenden stellte sich der Ablauf grundlegend anders dar als bei einer\n                    Therapieziel\u00e4nderung mit anschlie\u00dfender palliativen Versorgung\n                    in Anwesenheit der Eltern. Angesichts der gro\u00dfen emotionalen\n                    Herausforderungen erwiesen sich die Einbindung aller Beteiligten in die\n                    Entscheidungsabl\u00e4ufe und die \u00dcbernahme der besonderen\n                    Verantwortung als hilfreich.<\/jats:p>","DOI":"10.1055\/a-1509-3688","type":"journal-article","created":{"date-parts":[[2021,8,12]],"date-time":"2021-08-12T22:51:34Z","timestamp":1628808694000},"page":"366-370","source":"Crossref","is-referenced-by-count":0,"title":["...\u2009denn wir d\u00fcrfen sie nicht vergessen! Organspende\n                    in der Neonatologie"],"prefix":"10.1055","volume":"225","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7303-6667","authenticated-orcid":false,"given":"Christof","family":"Dame","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Neonatologie, Charit\u00e9 \u2013\n                    Universit\u00e4tsmedizin Berlin, Berlin, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kerstin","family":"von der Hude","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Neonatologie, Charit\u00e9 \u2013\n                    Universit\u00e4tsmedizin Berlin, Berlin, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Markus","family":"Kliemann","sequence":"additional","affiliation":[{"name":"Region Nord-Ost, Deutsche Stiftung Organtransplantation, Frankfurt,\n                    Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bianka","family":"R\u00f6sner","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Neonatologie, Charit\u00e9 \u2013\n                    Universit\u00e4tsmedizin Berlin, Berlin, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christoph","family":"B\u00fchrer","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Neonatologie, Charit\u00e9 \u2013\n                    Universit\u00e4tsmedizin Berlin, Berlin, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lars","family":"Garten","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Neonatologie, Charit\u00e9 \u2013\n                    Universit\u00e4tsmedizin Berlin, Berlin, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2021,8,12]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"2089","DOI":"10.1056\/NEJMp1809147","article-title":"Of tragedies and miracles - Neonatal organ donation","volume":"379","author":"B E Lechner","year":"2018","journal-title":"N Engl J Med"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1055\/s-0043-124677","article-title":"Neue Herausforderungen: Feststellung des irreversiblen Ausfalls der Hirnfunktion\n                    bei Neugeborenen, Kindern und Jugendlichen","volume":"230","author":"F Masuhr","year":"2018","journal-title":"Klin P\u00e4diatr"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1016\/j.jpeds.2009.07.019","article-title":"Categorizing neonatal deaths: a cross-cultural study in the United States,\n                    Canada, and The Netherlands","volume":"156","author":"A A Verhagen","year":"2010","journal-title":"J Pediatr"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1055\/s-0033-1361104","article-title":"Behandlung der neonatalen Asphyxie unter besonderer Ber\u00fccksichtigung der\n                    therapeutischen Hypothermie","volume":"226","author":"A W Flemmer","year":"2014","journal-title":"Klin P\u00e4diatr"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"CD003311","DOI":"10.1002\/14651858.CD003311.pub3","article-title":"Cooling for newborns with hypoxic ischaemic encephalopathy","author":"S E Jacobs","year":"2013","journal-title":"Cochrane Database Syst Rev"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"F225","DOI":"10.1136\/archdischild-2013-304803","article-title":"The potential for neonatal organ donation in a children\u2019s hospital","volume":"99","author":"E Charles","year":"2014","journal-title":"Arch Dis Child Fetal Neonatal 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Ethical insights and policy implications","volume":"12","author":"M U Ahmad","year":"2019","journal-title":"J Neonatal Perinatal Med"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"2545","DOI":"10.3109\/14767058.2015.1094785","article-title":"Does therapeutic hypothermia reduce acute kidney injury among term neonates with\n                    perinatal asphyxia?--a randomized controlled trial","volume":"29","author":"V Tanigasalam","year":"2016","journal-title":"J Matern Fetal Neonatal Med"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1097\/PCC.0b013e3181668605","article-title":"Pediatric organ donation: what factors most influence parents' donation\n                    decisions?","volume":"9","author":"J R Rodrigue","year":"2008","journal-title":"Pediatr Crit Care Med"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"837","DOI":"10.1136\/archdischild-2018-316382","article-title":"Parents\u2019 experiences of requests for organ and tissue donation: the\n                    value of asking","volume":"104","author":"A S Darlington","year":"2019","journal-title":"Arch Dis Child"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"587","DOI":"10.3389\/fphar.2020.00587","article-title":"A physiology-based pharmacokinetic framework to support drug development and\n                    dose precision during therapeutic hypothermia in neonates","volume":"11","author":"A Smits","year":"2020","journal-title":"Front Pharmacol"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1177\/1971400916678229","article-title":"Hypothermia-treated neonates with hypoxic-ischemic encephalopathy: Optimal\n                    timing of quantitative ADC measurement to predict disease severity","volume":"30","author":"Y K Lee","year":"2017","journal-title":"Neuroradiol J"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"e13679","DOI":"10.1111\/petr.13679","article-title":"Pediatric donor management to optimize donor heart utilization","volume":"24","author":"D Zimpfer","year":"2020","journal-title":"Pediatr Transplant"}],"container-title":["Zeitschrift f\u00fcr Geburtshilfe und 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