{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,25]],"date-time":"2024-07-25T04:41:25Z","timestamp":1721882485033},"reference-count":27,"publisher":"Georg Thieme Verlag KG","issue":"04","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tierarztl Prax Ausg G Grosstiere Nutztiere"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Das West-Nil-Virus (WNV) ist ein von M\u00fccken \u00fcbertragenes virales Pathogen mit weltweiter Bedeutung und eines der am meisten verbreiteten Flaviviren. Infektionen mit dem WNV wurden erstmalig im Jahr 2018 in Deutschland nachgewiesen und sind aufgrund der zunehmend milderen Winter mit feuchtwarmem Fr\u00fchjahr in Zukunft h\u00e4ufiger zu erwarten. Das WNV zirkuliert haupts\u00e4chlich in einem enzootischen Zyklus zwischen ornithophilen M\u00fccken und bestimmten Wildvogelarten. Menschen und Pferde sind Fehlwirte (\u201edead-end hosts\u201d) einer WNV-Infektion, erkranken h\u00e4ufig nicht, doch k\u00f6nnen einige von ihnen nach Viruskontakt milde fieberhafte Symptome (sog. \u201eWest-Nil-Fieber\u201c) bis hin zu schweren Gehirnentz\u00fcndungen mit t\u00f6dlichem Ausgang entwickeln. Deshalb ist es wichtig, die klinischen Symptome beim Pferd zu kennen und von anderen Differenzialdiagnosen zu unterscheiden. Im Fokus dieses Fallberichts steht daher, weniger bekannte Symptome einer WNV-Infektion wie unspezifisches Fieber, Anorexie oder kolik\u00e4hnliche Symptome konkret aufzuzeigen. Weiterhin werden m\u00f6gliche Differenzialdiagnosen erl\u00e4utert und durchgef\u00fchrte Therapien dargelegt. Zudem wurde der Verlauf des Titers neutralisierender Antik\u00f6rper nach einer Feldinfektion \u00fcber mehrere Monate verfolgt. Auch 7 Monate nach der Infektion lag der Titer noch auf einem hohen Niveau. Anschlie\u00dfend konnte nach einmaliger WNV-Impfung eine sehr gute immunologische Reaktion nachgewiesen werden.<\/jats:p>","DOI":"10.1055\/a-1519-4547","type":"journal-article","created":{"date-parts":[[2021,8,23]],"date-time":"2021-08-23T22:33:51Z","timestamp":1629758031000},"page":"281-286","source":"Crossref","is-referenced-by-count":0,"title":["Best\u00e4tigte West-Nil-Virus-Infektion bei einem Pferd mit minimalen neurologischen Symptomen und g\u00fcnstigem klinischem Verlauf"],"prefix":"10.1055","volume":"49","author":[{"given":"Dagmar S.","family":"Trachsel","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Pferde, allgemeine Chirurgie und Radiologie, Freie Universit\u00e4t Berlin"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karolina","family":"Drozdzewska","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Pferde, allgemeine Chirurgie und Radiologie, Freie Universit\u00e4t Berlin"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felicitas","family":"Bergmann","sequence":"additional","affiliation":[{"name":"Friedrich-Loeffler-Institut, Institut f\u00fcr neue und neuartige Tierseuchenerreger, Greifswald-Insel Riems"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ute","family":"Ziegler","sequence":"additional","affiliation":[{"name":"Friedrich-Loeffler-Institut, Institut f\u00fcr neue und neuartige Tierseuchenerreger, Greifswald-Insel Riems"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heidrun","family":"Gehlen","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Pferde, allgemeine Chirurgie und Radiologie, Freie Universit\u00e4t Berlin"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2021,8,23]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"240","DOI":"10.21836\/Pem20190305","article-title":"West Nile Virus 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