{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T22:09:08Z","timestamp":1759961348719},"reference-count":30,"publisher":"Georg Thieme Verlag KG","issue":"10\/11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Planta Med"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>As part of a validation program of antimalarial traditional recipes, an ethnotherapeutic approach was applied in Dionfo, a meso-endemic Guinean rural area where conventional health facilities are insufficient. A prevalence investigation indicated a malarial burden of 4.26%. Ethnomedical and ethnobotanical surveys led to a collection of 63 plant species used against malaria from which Terminalia albida (Combretaceae) was one of the most cited. Ethnotherapeutic evaluation of a remedy based on T. albida was applied to 9 voluntary patients suffering from uncomplicated malaria. Treatment of 7 to 14\u00a0days led to an improvement of clinical symptoms and a complete parasite clearance achievement of 8\/9 patients without side effects. In addition to antiplasmodial activity in vitro and in vivo previously described, this study indicates an efficacy to support the antimalarial traditional use of T. albida, which could constitute a first-aid treatment\n\t\t\t\t\twhen access to other medicines is delayed in the Dionfo community. Ethnotherapeutical investigation could be a valuable approach to guide subsequent investigations on traditional remedies.<\/jats:p>","DOI":"10.1055\/a-1519-5847","type":"journal-article","created":{"date-parts":[[2021,7,6]],"date-time":"2021-07-06T22:43:32Z","timestamp":1625611412000},"page":"850-859","source":"Crossref","is-referenced-by-count":1,"title":["Malaria in Guinean Rural Areas: Prevalence, Management, and Ethnotherapeutic Investigations in Dionfo, Sub-Prefecture of Labe"],"prefix":"10.1055","volume":"87","author":[{"given":"Aliou Mamadou","family":"Bald\u00e9","sequence":"additional","affiliation":[{"name":"Institut de Recherche et de D\u00e9veloppement des Plantes M\u00e9dicinales et Alimentaires de Guin\u00e9e, Dubr\u00e9ka, BP 6411 Conakry, Guin\u00e9e"},{"name":"Facult\u00e9 des Sciences et Techniques de la Sant\u00e9, Universit\u00e9 Gamal Abdel Nasser de Conakry, Guin\u00e9e"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alpha Oumar","family":"Balde","sequence":"additional","affiliation":[{"name":"Facult\u00e9 des Sciences et Techniques de la Sant\u00e9, Universit\u00e9 Gamal Abdel Nasser de Conakry, Guin\u00e9e"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bilo","family":"Bah","sequence":"additional","affiliation":[{"name":"Facult\u00e9 des Sciences et Techniques de la Sant\u00e9, Universit\u00e9 Gamal Abdel Nasser de Conakry, Guin\u00e9e"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Halimatou","family":"Barry","sequence":"additional","affiliation":[{"name":"Facult\u00e9 des Sciences et Techniques de la Sant\u00e9, Universit\u00e9 Gamal Abdel Nasser de Conakry, Guin\u00e9e"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saidou","family":"Traore","sequence":"additional","affiliation":[{"name":"Institut de Recherche et de D\u00e9veloppement des Plantes M\u00e9dicinales et Alimentaires de Guin\u00e9e, Dubr\u00e9ka, BP 6411 Conakry, Guin\u00e9e"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatoumata","family":"Bah","sequence":"additional","affiliation":[{"name":"Facult\u00e9 des Sciences, Universit\u00e9 Julius Ny\u00e9r\u00e9r\u00e9 de Kankan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mamadou Aliou","family":"Balde","sequence":"additional","affiliation":[{"name":"Facult\u00e9 des Sciences et Techniques de la Sant\u00e9, Universit\u00e9 Gamal Abdel Nasser de Conakry, Guin\u00e9e"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aissata","family":"Camara","sequence":"additional","affiliation":[{"name":"Facult\u00e9 des Sciences et Techniques de la Sant\u00e9, Universit\u00e9 Gamal Abdel Nasser de Conakry, Guin\u00e9e"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed Sahar","family":"Traore","sequence":"additional","affiliation":[{"name":"Institut de Recherche et de D\u00e9veloppement des Plantes M\u00e9dicinales et Alimentaires de Guin\u00e9e, Dubr\u00e9ka, BP 6411 Conakry, Guin\u00e9e"},{"name":"Facult\u00e9 des Sciences et Techniques de la Sant\u00e9, Universit\u00e9 Gamal Abdel Nasser de Conakry, Guin\u00e9e"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elhadj Saidou","family":"Balde","sequence":"additional","affiliation":[{"name":"Institut de Recherche et de D\u00e9veloppement des Plantes M\u00e9dicinales et Alimentaires de Guin\u00e9e, Dubr\u00e9ka, BP 6411 Conakry, Guin\u00e9e"},{"name":"Facult\u00e9 des Sciences et Techniques de la Sant\u00e9, Universit\u00e9 Gamal Abdel Nasser de Conakry, Guin\u00e9e"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ibrahima Kalil","family":"Sylla","sequence":"additional","affiliation":[{"name":"Institut de Recherche et de D\u00e9veloppement des Plantes M\u00e9dicinales et Alimentaires de Guin\u00e9e, Dubr\u00e9ka, BP 6411 Conakry, Guin\u00e9e"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sadou","family":"Diallo","sequence":"additional","affiliation":[{"name":"Tradith\u00e9rapeute professionnel, Dionfo-Centre, Lab\u00e9, Guin\u00e9e"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2021,7,6]]},"reference":[{"key":"ref1","volume-title":"Plan Strat\u00e9gique National de Lutte Contre le Paludisme 2013 \u2013 2017. 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