{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T01:13:33Z","timestamp":1782695613754,"version":"3.54.5"},"reference-count":5,"publisher":"Georg Thieme Verlag KG","issue":"01","funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["81670730"],"award-info":[{"award-number":["81670730"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["81100583"],"award-info":[{"award-number":["81100583"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Research Project of Hunan Health Committee","award":["202103061081"],"award-info":[{"award-number":["202103061081"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Horm Metab Res"],"published-print":{"date-parts":[[2022,1]]},"abstract":"Dear Editor<\/jats:title>Luo et al. 1 reported two cases of autosomal\n dominant pseudohypoparathyroidism type 1B (AD-PHP1B) and reviewed literature about\n the genetic and epigenetic characteristics of AD-PHP1B. Pseudohypoparathyroidism\n (PHP) is a cluster of heterogeneous diseases characterized by hypocalcemia and\n hyperphosphatemia due to resistance to parathyroid hormone (PTH). PHP1B almost\n results from methylation abnormalities of the maternal differentially methylated\n regions (DMRs) and can be divided into sporadic PHP1B and AD-PHP1B 1. As mentioned in this article 1, AD-PHP1B is caused by heterozygous maternal\n deletions within GNAS or STX16, which are associated with loss of methylation at the\n A\/B DMR alone or at all maternally methylated GNAS exons. While sporadic\n PHP1B remains unclear at the molecular level, except for approximately 10%\n of the patients caused by paternal uniparental isodisomy or heterodisomy involving\n chromosome 20q (patUPD20q) 2. Here, we would\n like to present a rare case of sporadic PHP1B occurring in association with\n hypokalemia.<\/jats:p>","DOI":"10.1055\/a-1528-7471","type":"journal-article","created":{"date-parts":[[2021,7,30]],"date-time":"2021-07-30T05:14:11Z","timestamp":1627622051000},"page":"50-51","source":"Crossref","is-referenced-by-count":6,"title":["A Case of Sporadic Pseudohypoparathyroidism Type 1B Presented with\n Hypokalemia"],"prefix":"10.1055","volume":"54","author":[{"given":"Wen-jun","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, The Third Xiangya Hospital Central South\n University, Changsha, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qin","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, The Third Xiangya Hospital Central South\n University, Changsha, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7835-076X","authenticated-orcid":false,"given":"Ping","family":"Jin","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, The Third Xiangya Hospital Central South\n University, Changsha, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2021,7,29]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1055\/a-1341-9891","article-title":"Genetic and epigenetic characteristics of autosomal dominant\n pseudohypoparathyroidism type 1B: case reports and literature review","volume":"53","author":"D Luo","year":"2021","journal-title":"Horm Metab Res"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"E103","DOI":"10.1210\/jc.2012-2639","article-title":"Pseudohypoparathyroidism type 1b due to paternal uniparental disomy of\n chromosome 20q","volume":"98","author":"A Dixit","year":"2013","journal-title":"J Clin Endocrinol Metab"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1186\/s13148-015-0121-1","article-title":"Global analysis of DNA methylation in hepatocellular carcinoma by a liquid\n hybridization capture-based bisulfite sequencing approach","volume":"7","author":"F Gao","year":"2015","journal-title":"Clin Epigenetics"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1507\/endocrj1954.28.595","article-title":"A case report of pseudohypoparathyroidism (Drezner's type I) associated\n with probable Bartter's syndrome","volume":"28","author":"K Iba","year":"1981","journal-title":"Endocrinol Jpn"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1172\/JCI0215219","article-title":"1,25-Dihydroxyvitamin D(3) is a negative endocrine regulator of the\n renin-angiotensin system","volume":"110","author":"Y C Li","year":"2002","journal-title":"J Clin Invest"}],"container-title":["Hormone and Metabolic Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-1528-7471.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,5]],"date-time":"2022-01-05T23:54:22Z","timestamp":1641426862000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-1528-7471"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7,29]]},"references-count":5,"journal-issue":{"issue":"01","published-online":{"date-parts":[[2022,1,5]]},"published-print":{"date-parts":[[2022,1]]}},"URL":"https:\/\/doi.org\/10.1055\/a-1528-7471","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0018-5043","1439-4286"],"issn-type":[{"value":"0018-5043","type":"print"},{"value":"1439-4286","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,7,29]]}}}