{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T08:32:50Z","timestamp":1740126770105,"version":"3.37.3"},"reference-count":32,"publisher":"Georg Thieme Verlag KG","issue":"05","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Laryngorhinootologie"],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>\n          Hintergrund\u2002Ziel dieser Arbeit war es, verschiedene Aspekte des Kapseldefekts eines pleomorphen Adenoms zu beleuchten und den Einfluss dieses Faktors mithilfe der vorliegenden Daten und der relevanten Literatur auf das Rezidivrisiko zu analysieren.<\/jats:p><jats:p>\n          Material und Methoden\u2002Es handelt sich um eine retrospektive Analyse aller Patienten, welche zwischen 2005 und 2020 bei einem pleomorphen Adenom der Glandula parotidea behandelt wurden. Es erfolgte eine erneute histopathologische Untersuchung der Paraffinbl\u00f6cke aller F\u00e4lle sowie eine Analyse der patientenbezogenen Daten, des Ausma\u00dfes des prim\u00e4ren operativen Eingriffs und des Rezidivrisikos. Die Nachsorgeuntersuchung erfolgte im Sinne einer klinischen und sonografischen Untersuchung.<\/jats:p><jats:p>\n          Ergebnisse\u2002Insgesamt wurden 845 Patienten in einer Datenbank erfasst. Hierunter fanden sich 7 (0,8\u200a%) Rezidive, jedoch alle bei \u201ein sano\u201c resezierten Tumoren. Positive R\u00e4nder zeigten sich in 37 F\u00e4llen (4,4\u200a%). Bei 13 der 37 F\u00e4lle war dies intraoperativ festgestellt worden, wohingegen der Defekt bei 24 der 37 F\u00e4lle erst histopathologisch identifiziert wurde. Bei den 13 F\u00e4llen der makroskopischen Tumorer\u00f6ffnung wurde in 2 F\u00e4llen bei der sonografischen Untersuchung der Verdacht auf ein unilokul\u00e4res Rezidiv des pleomorphen Adenoms gestellt, welches zun\u00e4chst sonografisch kontrolliert wurde.<\/jats:p><jats:p>\n          Schlussfolgerung\u2002Die positiven R\u00e4nder beim parotidealen pleomorphen Adenom scheinen nicht zwangsl\u00e4ufig zum vorprogrammierten Rezidiv zu f\u00fchren.<\/jats:p>","DOI":"10.1055\/a-1528-7821","type":"journal-article","created":{"date-parts":[[2021,6,22]],"date-time":"2021-06-22T22:40:39Z","timestamp":1624401639000},"page":"408-413","source":"Crossref","is-referenced-by-count":0,"title":["Der Einfluss des Kapseldefektes als Risikofaktor f\u00fcr die Rezidivbildung beim pleomorphen Adenom der Glandula parotidea"],"prefix":"10.1055","volume":"101","author":[{"given":"Peter","family":"Buchta","sequence":"additional","affiliation":[{"name":"Hals-Nasen-Ohren-Klinik, Kopf- und Halschirurgie, Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg (FAU), Erlangen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vivian","family":"Thimsen","sequence":"additional","affiliation":[{"name":"Hals-Nasen-Ohren-Klinik, Kopf- und Halschirurgie, Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg (FAU), Erlangen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ann-Kristin","family":"Iro","sequence":"additional","affiliation":[{"name":"Hals-Nasen-Ohren-Klinik, Kopf- und Halschirurgie, Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg (FAU), Erlangen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abbas","family":"Agaimy","sequence":"additional","affiliation":[{"name":"Pathologisches Institut, Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg (FAU), Erlangen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heinrich","family":"Iro","sequence":"additional","affiliation":[{"name":"Hals-Nasen-Ohren-Klinik, Kopf- und Halschirurgie, Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg (FAU), Erlangen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4948-8882","authenticated-orcid":false,"given":"Konstantinos","family":"Mantsopoulos","sequence":"additional","affiliation":[{"name":"Hals-Nasen-Ohren-Klinik, Kopf- und Halschirurgie, Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg (FAU), Erlangen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2021,6,22]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1002\/bjs.18002811102","article-title":"The treatment of tumours of the parotid gland with special reference to total parotidectomy","volume":"28","author":"H Bailey","year":"1941","journal-title":"Br J Surg"},{"key":"ref2","first-page":"23","article-title":"Mysterious mixed tumors of salivary glands","author":"J Mc Farland","year":"1943","journal-title":"Surg Gynecol Obstet"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1136\/bmj.2.4569.245","article-title":"The surgical anatomy of the parotid gland","volume":"2","author":"H Bailey","year":"1948","journal-title":"BMJ"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"404","DOI":"10.1016\/0266-4356(90)90040-r","article-title":"Management of the parotid pleomorphic adenoma, the problem of exposing tumour tissue at operation. 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