{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,4,26]],"date-time":"2024-04-26T14:32:39Z","timestamp":1714141959256},"reference-count":46,"publisher":"Georg Thieme Verlag KG","issue":"08","license":[{"start":{"date-parts":[[2021,8,3]],"date-time":"2021-08-03T00:00:00Z","timestamp":1627948800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Psychiatr Prax"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Seit Dezember 2020 stehen in der Europ\u00e4ischen Union Impfstoffe gegen SARS-CoV-2 zur Verf\u00fcgung. Psychisch erkrankte Personen haben ein erh\u00f6htes Risiko f\u00fcr einen schweren oder t\u00f6dlichen Verlauf einer SARS-CoV-2-Infektion. So stellt sich die Frage, inwiefern Interaktionen zwischen den neuen SARS-CoV-2-Impfstoffen und Psychopharmaka zu erwarten sind. Grunds\u00e4tzlich fehlen bislang noch konkrete Daten \u00fcber die Vertr\u00e4glichkeit und Wirksamkeit einer Impfung gegen SARS-CoV-2 unter Psychopharmakotherapie \u2013 aus Untersuchungen zu Impfstoffen gegen andere Krankheitserreger lassen sich jedoch potenzielle Interaktionen ableiten, wie zum Beispiel eine reduzierte Immunantwort mit geringerer klinischer Wirksamkeit oder eine Erh\u00f6hung von Medikamentenspiegeln aufgrund einer indirekten Hemmung von metabolisierenden Enzymen durch Impfstoffe. Andererseits zeigen depressive Patienten, die mit Antidepressiva medikament\u00f6s behandelt werden, eine bessere Immunantwort.<\/jats:p>","DOI":"10.1055\/a-1531-4460","type":"journal-article","created":{"date-parts":[[2021,8,3]],"date-time":"2021-08-03T22:48:01Z","timestamp":1628030881000},"page":"399-403","source":"Crossref","is-referenced-by-count":2,"title":["COVID-19-Impfung unter Psychopharmakotherapie"],"prefix":"10.1055","volume":"48","author":[{"given":"Johanna","family":"Seifert","sequence":"first","affiliation":[{"name":"Klinik f\u00fcr Psychiatrie, Sozialpsychiatrie und Psychotherapie, Medizinische Hochschule Hannover, Hannover"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johannes","family":"Heck","sequence":"first","affiliation":[{"name":"Institut f\u00fcr Klinische Pharmakologie, Medizinische Hochschule Hannover, 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