{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T17:35:26Z","timestamp":1758476126563},"reference-count":29,"publisher":"Georg Thieme Verlag KG","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Horm Metab Res"],"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Vitamin D deficiency is a major widespread health concern and is linked to a high\nrisk of cardiovascular disease (CVD). Thus, we have investigated the association\nof vitamin D with various CVD risk markers. The present study comprises 90\ncontrol and 90 type 2 diabetes mellitus (T2DM) subjects of both sexes (age\nrange, 30\u201350 years). The 25 hydroxyvitamin D [25(OH)D] and CVD risk\nmarkers including high sensitive C-reactive protein (hs-CRP), monocyte\nchemoattractant protein-1 (MCP-1), intact parathyroid hormone (I-PTH),\nfibroblast growth factor (FGF)-23, erythrocyte sedimentation rate (ESR), and\nfibrinogen were measured by using standard assays. Blood viscosity and\natherogenic index of plasma calculated using standard formulae. The ten-year\ncardiovascular risk was assessed using the Framingham risk score (FRS). 25(OH)D,\nhs-CRP, MCP-1, FGF-23, ESR, fibrinogen, atherogenic index of plasma and FRS were\nsignificantly different between control and T2DM groups (p&lt;0.05).\n25(OH)D showed a significant negative correlation with MCP-1, ESR, blood\nviscosity, atherogenic index of plasma and FRS among total study subjects.\nFurther, logistics regression analysis showed an association of 25(OH)D with\nMCP-1, hematocrit, fibrinogen, and blood viscosity. The association between\n25(OH)D and various CVD risk markers suggests that 25(OH)D might help in the\nprediction of CVD risk.<\/jats:p>","DOI":"10.1055\/a-1534-2747","type":"journal-article","created":{"date-parts":[[2021,8,25]],"date-time":"2021-08-25T22:47:11Z","timestamp":1629931631000},"page":"676-682","source":"Crossref","is-referenced-by-count":3,"title":["Serum 25(OH)D Concentration and Cardiovascular Disease Risk Markers\nAmong Middle-Aged Healthy and Type 2 Diabetic Subjects"],"prefix":"10.1055","volume":"53","author":[{"given":"Yogita","family":"Dhas","sequence":"additional","affiliation":[{"name":"Symbiosis School of Biological Sciences, Symbiosis International\n(Deemed University), Lavale, Pune, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joyita","family":"Banerjee","sequence":"additional","affiliation":[{"name":"Symbiosis School of Biological Sciences, Symbiosis International\n(Deemed University), Lavale, Pune, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gauri","family":"Damle","sequence":"additional","affiliation":[{"name":"Madhunayani Diabetes Care & Eye Laser Centre, Pune,\nIndia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neetu","family":"Mishra","sequence":"additional","affiliation":[{"name":"Symbiosis School of Biological Sciences, Symbiosis International\n(Deemed University), Lavale, Pune, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2021,8,25]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"1605","DOI":"10.1161\/CIRCULATIONAHA.114.008729","article-title":"Cardiovascular diseases in India: current epidemiology and future\ndirections","volume":"133","author":"D Prabhakaran","year":"2016","journal-title":"Circulation"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1093\/ajcn\/79.3.362","article-title":"Vitamin D: importance 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