{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,6,28]],"date-time":"2024-06-28T00:11:17Z","timestamp":1719533477850},"reference-count":49,"publisher":"Georg Thieme Verlag KG","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Fortschr Neurol Psychiatr"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Die Pr\u00e4valenz von Traumatisierung bei schizophrenen Patienten ist\n                    h\u00f6her als in der Normalbev\u00f6lkerung. Meta-Analysen zeigen\n                    signifikante Zusammenh\u00e4nge zwischen traumatischen Kindheitserfahrungen\n                    und psychotischen Erkrankungen. Sowohl Patienten mit Schizophrenie, als auch\n                    solche mit Posttraumatischer Belastungsst\u00f6rung (PTBS) sind\n                    gekennzeichnet durch hirnmorphologische (Amygdala und Hippocampus)\n                    Ver\u00e4nderungen. Bei beiden Patientengruppen lassen sich zudem\n                    neuroendokrinologische Ver\u00e4nderungen (Cortisol und \u03b1-Amylase),\n                    aber auch ein schlechteres klinisches Outcome finden. In der psychodynamischen\n                    Theoriediskussion finden sich nur wenige Ans\u00e4tze zu Trauma und Psychose.\n                    Hier ist vor allem Frieda Fromm-Reichmann zu nennen, die schon fr\u00fch auf\n                    die gro\u00dfe Bedeutung kindlicher Traumatisierung vor allem von\n                    Misshandlung und sexuellem Missbrauch f\u00fcr die sp\u00e4tere Entstehung\n                    schizophrener Erkrankungen hinwies und erste Prinzipien analytischer\n                    Psychosetherapie mit der Bearbeitung der durch das Trauma verursachten tiefen\n                    Lebensangst im Hier und Jetzt der \u00dcbertragungssituation entwickelte. Es\n                    wird vermutet, dass schizophrene St\u00f6rungen und PTBS als\n                    Trauma-Folgeerkrankungen aufzufassen sind, die in einem bislang unbekannten\n                    Ma\u00dfe auch komorbid auftreten.<\/jats:p>","DOI":"10.1055\/a-1535-1655","type":"journal-article","created":{"date-parts":[[2021,8,13]],"date-time":"2021-08-13T22:38:07Z","timestamp":1628894287000},"page":"512-522","source":"Crossref","is-referenced-by-count":0,"title":["Traumatisierung und schizophrene St\u00f6rungen \u2013 eine\n                    mehrdimensionale Betrachtung"],"prefix":"10.1055","volume":"90","author":[{"given":"Georg","family":"Juckel","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Psychiatrie, Psychotherapie und\n                    Pr\u00e4ventivmedizin, LWL-Universit\u00e4tsklinikum,\n                    Ruhr-Universit\u00e4t Bochum"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paraskevi","family":"Mavrogiorgou","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Psychiatrie, Psychotherapie und\n                    Pr\u00e4ventivmedizin, LWL-Universit\u00e4tsklinikum,\n                    Ruhr-Universit\u00e4t Bochum"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2021,8,13]]},"reference":[{"key":"ref1","first-page":"333","article-title":"Traumafolgest\u00f6rungen\u2013Diagnostik und Behandlung","volume":"55","author":"L Schellong","year":"2015","journal-title":"Internist Prax"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1037\/0022-006X.70.1.246","article-title":"Trauma exposure and posttraumatic stress disorder in psychosis: findings from a\n                    first-admission cohort","volume":"70","author":"Y Neria","year":"2002","journal-title":"J Consult Clin Psychol"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1016\/j.schres.2005.03.003","article-title":"Histories of childhood maltreatment in schizophrenia: relationships with\n                    premorbid functioning, symptomatology and cognitive deficits","volume":"76","author":"L S Schenkel","year":"2005","journal-title":"Schizophr Res"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1093\/schbul\/sbl053","article-title":"Environment and schizophrenia: environmental factors in schizophrenia: childhood\n                    trauma \u2013 a critical review","volume":"33","author":"C Morgan","year":"2007","journal-title":"Schizophr Bull"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"661","DOI":"10.1093\/schbul\/sbs050","article-title":"Childhood adversities increase the risk of psychosis: a meta-analysis of\n                    patient-control, prospective- and cross-sectional cohort studies","volume":"38","author":"F Varese","year":"2012","journal-title":"Schizophr Bull"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1016\/j.schres.2018.06.043.","article-title":"Gender differences in childhood trauma in first episode psychosis: Association\n                    with symptom severity over two years","volume":"205","author":"M Pruessner","year":"2019","journal-title":"Schizophr Res"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"485","DOI":"10.1007\/s10597-009-9248-x","article-title":"Trauma and posttraumatic stress disorder (PTSD) in patients with schizophrenia\n                    or schizoaffective disorder","volume":"45","author":"MJ J Lommen","year":"2009","journal-title":"Community Ment Health J"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"697","DOI":"10.1093\/schbul\/sbt032","article-title":"Sexual trauma increases the risk of developing psychosis in an ultra high-risk\n                    \u201eprodromal\u201c population","volume":"40","author":"A D Thompson","year":"2014","journal-title":"Schizophr Bull"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1111\/j.1600-0447.2010.01542.x","article-title":"Experience of trauma and conversion to\n                    psychosis in an ultra-high-risk (prodromal) group","volume":"121","author":"A Bechdolf","year":"2010","journal-title":"Acta\n                    Psychiatr Scand"},{"key":"ref10","first-page":"161","article-title":"The European Prediction of Psychosis Study (EPOS): integrating early recognition\n                    and intervention in Europe","volume":"4","author":"J Klosterk\u00f6tter","year":"2005","journal-title":"World Psychiatry"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"935","DOI":"10.1111\/eip.12714","article-title":"Childhood adversity predicts persistence of suicidal thoughts differently in\n                    females and males at clinical high-risk patients of psychosis. 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