{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,25]],"date-time":"2025-11-25T16:38:35Z","timestamp":1764088715652,"version":"3.45.0"},"reference-count":19,"publisher":"Georg Thieme Verlag KG","issue":"08","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Z Gastroenterol"],"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Fusarium spp. can cause invasive infection with fatal outcomes in immunocompromised patients. Therefore, invasive fusariosis is rare after solid organ transplantation. For this reason, experience and management are limited to single published case reports.<\/jats:p>\n                  <jats:p>We report a 65-year-old female patient with disseminated brain abscesses caused by Fusarium after liver transplantation (LT). The patient underwent LT for secondary sclerosing cholangitis after acute respiratory distress syndrome (ARDS). After a complicated course with aneurysm and thrombosis of the hepatic artery, re-transplantation was performed after one month. Due to inadequate awakening response, cerebral imaging was performed, which showed multiple abscesses. The patient died shortly thereafter, and an autopsy showed fusariosis.<\/jats:p>","DOI":"10.1055\/a-1535-2981","type":"journal-article","created":{"date-parts":[[2021,11,15]],"date-time":"2021-11-15T18:59:32Z","timestamp":1637002772000},"page":"1231-1234","source":"Crossref","is-referenced-by-count":3,"title":["Disseminated cerebral fusariosis in a liver-transplant patient: A case report and review of the literature"],"prefix":"10.1055","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2099-4009","authenticated-orcid":false,"given":"Pernilla","family":"Stropnicky","sequence":"additional","affiliation":[{"name":"Department of General, Visceral, Thoracic, Transplant and Pediatric Surgery, University Medical Centre Schleswig-Holstein - Campus Kiel, Kiel, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katharina","family":"He\u00df","sequence":"additional","affiliation":[{"name":"Department of Pathology, University Medical Centre Schleswig-Holstein - Campus Kiel, Kiel, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Becker","sequence":"additional","affiliation":[{"name":"Department of General, Visceral, Thoracic, Transplant and Pediatric Surgery, University Medical Centre Schleswig-Holstein - Campus Kiel, Kiel, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felix","family":"Braun","sequence":"additional","affiliation":[{"name":"Department of General, Visceral, Thoracic, Transplant and Pediatric Surgery, University Medical Centre Schleswig-Holstein - Campus Kiel, Kiel, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2021,11,15]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"695","DOI":"10.1128\/CMR.00014-07","article-title":"Fusarium infections in immunocompromised patients","volume":"20","author":"M Nucci","year":"2007","journal-title":"Clin Microbiol Rev"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"e20200013","DOI":"10.1590\/0037-8682-0013-2020","article-title":"Human fusariosis: an emerging infection that is difficult to treat","volume":"53","author":"BG Batista","year":"2020","journal-title":"Rev Soc Bras"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"417","DOI":"10.5414\/npp28417","article-title":"Disseminated Fusarium infection with brain abscesses in a lung transplant recipient","volume":"28","author":"BK Kleinschmidt-Demasters","year":"2009","journal-title":"Clin Neuropathol"},{"key":"ref4","first-page":"128","article-title":"Fusarium brain abscess in a patient with diabetes mellitus and liver cirrhosis","volume":"26","author":"Y-J Chen","year":"2017","journal-title":"Acta Neurol Taiwanica"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1111\/myc.12271","article-title":"Fusarium brain abscess: case report and literature review","volume":"58","author":"RR Garcia","year":"2015","journal-title":"Mycoses"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"e13344","DOI":"10.1111\/tid.13344","article-title":"Isolated pulmonary fusariosis caused by Neocosmospora pseudensiformis in a liver transplant recipient: a case report and review of the literature","volume":"22","author":"E Yamasmith","year":"2020","journal-title":"Transpl Infect Dis Off"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"1711","DOI":"10.1002\/lt.20899","article-title":"Systemic fungemia and hepatic localizations of Fusarium solani in a liver transplanted patient: an emerging fungal agent","volume":"12","author":"F Lodato","year":"2006","journal-title":"Liver Transpl"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"2718","DOI":"10.1016\/j.transproceed.2013.08.010","article-title":"Surveillance of bacterial and fungal infections in the postoperative period following liver transplantation: a series from 2005\u20132011","volume":"45","author":"G Sganga","year":"2013","journal-title":"Transplant Proc"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"e44","DOI":"10.1155\/2012\/272197","article-title":"Successful use of posaconazole to treat invasive cutaneous fungal infection in a liver transplant patient on sirolimus","volume":"23","author":"R Dahlan","year":"2012","journal-title":"Can J Infect Dis Med Microbiol"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"438","DOI":"10.1016\/j.diagmicrobio.2011.08.024","article-title":"Fusarium verticillioides fungemia in a liver transplantation patient: successful treatment with voriconazole","volume":"71","author":"S Cocchi","year":"2011","journal-title":"Diagn Microbiol Infect Dis"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"1237","DOI":"10.1086\/319753","article-title":"Fusarium infection after solid-organ transplantation","volume":"32","author":"P Sampathkumar","year":"2001","journal-title":"Clin Infect Dis"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"599","DOI":"10.1016\/j.transproceed.2010.01.004","article-title":"Cellulitis and nodular skin lesions due to Fusarium spp in liver transplant: case report","volume":"42","author":"M Halpern","year":"2010","journal-title":"Transplant Proc"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"236","DOI":"10.1179\/joc.2009.21.2.236","article-title":"Breakthrough Fusarium spp fungemia during caspofungin therapy in an ABO-incompatible orthotopic liver transplant patient","volume":"21","author":"C Tascini","year":"2009","journal-title":"J Chemother Florence Italy"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1186\/1752-1947-8-101","article-title":"Bilateral endogenous Fusarium solani endophthalmitis in a liver-transplanted patient: a case report","volume":"8","author":"JS J\u00f8rgensen","year":"2014","journal-title":"J Med Case Reports"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"598","DOI":"10.3171\/jns.1983.58.4.0598","article-title":"Fusarium brain abscess: case report","volume":"58","author":"GK Steinberg","year":"1983","journal-title":"J Neurosurg"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1128\/CMR.00053-10","article-title":"Histopathologic diagnosis of fungal infections in the 21st century","volume":"24","author":"J Guarner","year":"2011","journal-title":"Clin Microbiol Rev"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"1491","DOI":"10.1007\/s10096-013-1924-7","article-title":"Fusariosis, a complex infection caused by a high diversity of fungal species refractory to treatment","volume":"32","author":"J Guarro","year":"2013","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"1398","DOI":"10.1086\/503425","article-title":"Posaconazole as salvage treatment for invasive fusariosis in patients with underlying hematologic malignancy and other conditions","volume":"42","author":"II Raad","year":"2006","journal-title":"Clin Infect Dis"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"3298","DOI":"10.1128\/AAC.46.10.3298-3300.2002","article-title":"In vitro activities of investigational triazoles against Fusarium species: effects of inoculum size and incubation time on broth microdilution susceptibility test results","volume":"46","author":"NI Paphitou","year":"2002","journal-title":"Antimicrob Agents Chemother"}],"container-title":["Zeitschrift f\u00fcr Gastroenterologie"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-1535-2981.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,25]],"date-time":"2025-11-25T16:31:28Z","timestamp":1764088288000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-1535-2981"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,15]]},"references-count":19,"journal-issue":{"issue":"08","published-online":{"date-parts":[[2022,8,12]]},"published-print":{"date-parts":[[2022,8]]}},"URL":"https:\/\/doi.org\/10.1055\/a-1535-2981","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0044-2771","1439-7803"],"issn-type":[{"type":"print","value":"0044-2771"},{"type":"electronic","value":"1439-7803"}],"subject":[],"published":{"date-parts":[[2021,11,15]]}}}