{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T22:13:08Z","timestamp":1783462388807,"version":"3.55.0"},"reference-count":96,"publisher":"Georg Thieme Verlag KG","issue":"08","license":[{"start":{"date-parts":[[2021,6,24]],"date-time":"2021-06-24T00:00:00Z","timestamp":1624492800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Thromb Haemost"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background\u2003One year after the declaration of the coronavirus disease 2019 (COVID-19) pandemic by the World Health Organization (WHO) and despite the implementation of mandatory physical barriers and social distancing, humanity remains challenged by a long-lasting and devastating public health crisis.<\/jats:p><jats:p>\n          Management\u2003Non-pharmacological interventions (NPIs) are efficient mitigation strategies. The success of these NPIs is dependent on the approval and commitment of the population. The launch of a mass vaccination program in many countries in late December 2020 with mRNA vaccines, adenovirus-based vaccines, and inactivated virus vaccines has generated hope for the end of the pandemic.<\/jats:p><jats:p>\n          Current Issues\u2003The continuous appearance of new pathogenic viral strains and the ability of vaccines to prevent infection and transmission raise important concerns as we try to achieve community immunity against severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) and its variants. The need of a second and even third generation of vaccines has already been acknowledged by the WHO and governments.<\/jats:p><jats:p>\n          Perspectives\u2003There is a critical and urgent need for a balanced and integrated strategy for the management of the COVID-19 outbreaks organized on three axes: (1) Prevention of the SARS-CoV-2 infection, (2) Detection and early diagnosis of patients at risk of disease worsening, and (3) Anticipation of medical care (PDA).<\/jats:p><jats:p>\n          Conclusion\u2003The \u201cPDA strategy\u201d integrated into state policy for the support and expansion of health systems and introduction of digital organizations (i.e., telemedicine, e-Health, artificial intelligence, and machine-learning technology) is of major importance for the preservation of citizens' health and life world-wide.<\/jats:p>","DOI":"10.1055\/a-1535-8807","type":"journal-article","created":{"date-parts":[[2021,6,25]],"date-time":"2021-06-25T01:06:16Z","timestamp":1624583176000},"page":"992-1007","source":"Crossref","is-referenced-by-count":27,"title":["The COVID-19 Pandemic and the Need for an Integrated and Equitable Approach: An International Expert Consensus Paper"],"prefix":"10.1055","volume":"121","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2316-6348","authenticated-orcid":false,"given":"Grigoris T.","family":"Gerotziafas","sequence":"additional","affiliation":[{"name":"Sorbonne Universit\u00e9, INSERM, UMR_S 938, Research Group Cancer, Biology and Therapeutics, Centre de recherche Saint-Antoine (CRSA), Institut Universitaire de Canc\u00e9rologie, Paris, France"},{"name":"Thrombosis Center, Tenon-Saint Antoine, H\u00f4pitaux Universitaires de l'Est Parisien, Assistance Publique H\u00f4pitaux de Paris (APHP), France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariella","family":"Catalano","sequence":"additional","affiliation":[{"name":"Research Center on Vascular Disease & Angiology Unit, Department of Biomedical Science, L Sacco Hospital, University of Milan, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiannis","family":"Theodorou","sequence":"additional","affiliation":[{"name":"Centre d'Immunologie et des Maladies Infectieuses UPMC UMRS CR7, Inserm U1135, CNRS ERL 8255, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick Van","family":"Dreden","sequence":"additional","affiliation":[{"name":"Sorbonne Universit\u00e9, INSERM, UMR_S 938, Research Group Cancer, Biology and Therapeutics, Centre de recherche Saint-Antoine (CRSA), Institut Universitaire de Canc\u00e9rologie, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent","family":"Marechal","sequence":"additional","affiliation":[{"name":"Sorbonne Universit\u00e9, INSERM, UMR_S 938, Research Group Cancer, Biology and Therapeutics, Centre de recherche Saint-Antoine (CRSA), Institut Universitaire de Canc\u00e9rologie, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex C.","family":"Spyropoulos","sequence":"additional","affiliation":[{"name":"Donald and Barbara Zucker School of Medicine at Hofstra\/Northwell, Hempstead, New York, United States"},{"name":"Department of Obstetrics and Gynecology, I.M. 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