{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T08:33:43Z","timestamp":1740126823802,"version":"3.37.3"},"reference-count":7,"publisher":"Georg Thieme Verlag KG","issue":"01","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gesundheitswesen"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Einleitung Seit Mai 2020 wurden die ersten POC Tests f\u00fcr die\n                    SARS-CoV-2 Diagnostik angeboten, welche mit der Notwendigkeit des\n                    nasopharyngealen Abstrichs verbunden waren. Aufgrund des langen Arbeitskanals\n                    durch die Nasenhaupth\u00f6hle besteht das Risiko einer Schleimhautverletzung\n                    mit konsekutiver Epistaxis.<\/jats:p><jats:p>\n          Methodik Wir beschreiben den Krankheitsverlauf zweier Patientinnen, bei\n                    denen es nach extern durchgef\u00fchrtem nasopharyngealen Test zu einer\n                    massiven interventionspflichtigen Epistaxis nasi kam.<\/jats:p><jats:p>\n          Ergebnisse Bei einer Patientin musste nach frustraner Nasentamponade eine\n                    endonasale Blutstillung in Intubationsnarkose durchgef\u00fchrt werden. Bei\n                    einer zweiten Patientin kam es zu einer Hb-relevanten Epistaxis nasi mit\n                    h\u00e4morrhagischem Schock. Sie wurde intubiert und beatmet\n                    station\u00e4r \u00fcbernommen.<\/jats:p><jats:p>\n          Schlussfolgerung Der transnasale Test in der SARS-CoV-2 Diagnostik\n                    f\u00fchrt in seltenen F\u00e4llen zu lebensbedrohlichen Komplikationen.\n                    Aufgrund der weltweit \u00fcber 5 Millionen t\u00e4glich\n                    durchgef\u00fchrten Tests im Rahmen der aktuellen Pandemie sind\n                    Komplikationen nicht zu vernachl\u00e4ssigen. Es ist unverzichtbar, dass die\n                    den Abstrich durchf\u00fchrende Person die Anatomie detailliert kennt.\n                    Alternative Testmethoden werden bez\u00fcglich ihrer Sensitivit\u00e4t\n                    weiter beurteilt. Hinsichtlich der auch zuk\u00fcnftig bestehenden\n                    Notwendigkeit von SARS-CoV-2-Tests ist eine weitere Etablierung alternativer und\n                    risiko\u00e4rmerer Testverfahren unerl\u00e4sslich.<\/jats:p>","DOI":"10.1055\/a-1537-9562","type":"journal-article","created":{"date-parts":[[2021,9,23]],"date-time":"2021-09-23T22:43:41Z","timestamp":1632437021000},"page":"27-30","source":"Crossref","is-referenced-by-count":1,"title":["Interventionsbed\u00fcrftige Epistaxis nasi nach\n                    SARS-CoV-2-Abstrich"],"prefix":"10.1055","volume":"84","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1028-9149","authenticated-orcid":false,"given":"Melanie","family":"Martin","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Hals-Nasen-Ohren-Heilkunde und Kopf-Hals-Chirurgie,\n                    University Ulm Medical Centre, Ulm, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jens","family":"Greve","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Hals-Nasen-Ohren-Heilkunde und Kopf-Hals-Chirurgie,\n                    University Ulm Medical Centre, Ulm, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas K.","family":"Hoffmann","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Hals-Nasen-Ohren-Heilkunde und Kopf-Hals-Chirurgie,\n                    University Ulm Medical Centre, Ulm, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janina","family":"Hahn","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Hals-Nasen-Ohren-Heilkunde und Kopf-Hals-Chirurgie,\n                    University Ulm Medical Centre, Ulm, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2021,9,23]]},"reference":[{"key":"ref2","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1038\/s41586-020-2196-x","article-title":"Virological assessment of hospitalized patients with COVID-2019","volume":"581","author":"R W\u00f6lfel","year":"2020","journal-title":"Nature"},{"key":"ref3","first-page":"1843","article-title":"Detection of SARS-CoV-2 in Different Types of Clinical Specimens","volume":"323","author":"W Wang","year":"2020","journal-title":"JAMA"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1056\/NEJMc2016321","article-title":"Swabs Collected by Patients or Health Care Workers for SARS-CoV-2 Testing","volume":"383","author":"Y P Tu","year":"2020","journal-title":"N Engl J Med"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1017\/ice.2020.229","article-title":"Pharynx gargle samples are suitable for SARS-CoV-2 diagnostic use and save\n                    personal protective equipment and swabs","volume":"42","author":"M Malecki","year":"2021","journal-title":"Infect Control Hosp Epidemiol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"1356","DOI":"10.1080\/22221751.2020.1775133","article-title":"Evaluating the use of posterior oropharyngeal saliva in a point-of-care assay\n                    for the detection of SARS-CoV-2","volume":"9","author":"J H Chen","year":"2020","journal-title":"Emerg Microbes Infect"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"e145","DOI":"10.1016\/j.jinf.2020.05.071","article-title":"Comparison of SARS-CoV-2 detection in nasopharyngeal swab and saliva","volume":"81","author":"S Iwasaki","year":"2020","journal-title":"J Infect"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1056\/NEJMc2016359","article-title":"Saliva or Nasopharyngeal Swab Specimens for Detection of SARS-CoV-2","volume":"383","author":"A L Wyllie","year":"2020","journal-title":"N Engl J Med"}],"container-title":["Das Gesundheitswesen"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-1537-9562.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,28]],"date-time":"2024-06-28T10:56:12Z","timestamp":1719572172000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-1537-9562"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9,23]]},"references-count":7,"journal-issue":{"issue":"01","published-online":{"date-parts":[[2022,1,13]]},"published-print":{"date-parts":[[2022,1]]}},"URL":"https:\/\/doi.org\/10.1055\/a-1537-9562","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0941-3790","1439-4421"],"issn-type":[{"type":"print","value":"0941-3790"},{"type":"electronic","value":"1439-4421"}],"subject":[],"published":{"date-parts":[[2021,9,23]]}}}