{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T12:23:40Z","timestamp":1790252620056,"version":"4.1.0"},"reference-count":37,"publisher":"Georg Thieme Verlag KG","issue":"04","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Endoscopy"],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background\u2002Clinical implementation of the resect-and-discard strategy has been difficult because optical diagnosis is highly operator dependent. This prospective study aimed to evaluate a resect-and-discard strategy that is not operator dependent.<\/jats:p><jats:p>\n          Methods\u2002The study evaluated a resect-and-discard strategy that uses the anatomical polyp location to classify colonic polyps into non-neoplastic or low risk neoplastic. All rectosigmoid diminutive polyps were considered hyperplastic and all polyps located proximally to the sigmoid colon were considered neoplastic. Surveillance interval assignments based on these a priori assumptions were compared with those based on actual pathology results and on optical diagnosis. The primary outcome was \u2265\u200a90\u200a% agreement with pathology in surveillance interval assignment.<\/jats:p><jats:p>\n          Results\u20021117 patients undergoing complete colonoscopy were included and 482 (43.1\u200a%) had at least one diminutive polyp.\u200aSurveillance interval agreement between the location-based strategy and pathological findings using the 2020 US Multi-Society Task Force guideline was 97.0\u200a% (95\u200a% confidence interval [CI] 0.96\u20130.98), surpassing the \u2265\u200a90\u200a% benchmark. Optical diagnoses using the NICE and Sano classifications reached 89.1\u200a% and 90.01\u200a% agreement, respectively (P\u200a&lt;\u200a0.001), and were inferior to the location-based strategy. The location-based resect-and-discard strategy allowed a 69.7\u200a% (95\u200a%CI 0.67\u20130.72) reduction in pathology examinations compared with 55.3\u200a% (95\u200a%CI 0.52\u20130.58; NICE and Sano) and 41.9\u200a% (95\u200a%CI 0.39\u20130.45; WASP) with optical diagnosis.<\/jats:p><jats:p>\n          Conclusion\u2002The location-based resect-and-discard strategy achieved very high surveillance interval agreement with pathology-based surveillance interval assignment, surpassing the \u2265\u200a90\u200a% benchmark and outperforming optical diagnosis in surveillance interval agreement and the number of pathology examinations avoided.<\/jats:p>","DOI":"10.1055\/a-1546-9169","type":"journal-article","created":{"date-parts":[[2021,8,27]],"date-time":"2021-08-27T00:28:10Z","timestamp":1630024090000},"page":"354-363","source":"Crossref","is-referenced-by-count":20,"title":["The location-based resect and discard strategy for diminutive colorectal polyps: a prospective clinical 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Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Deslandres","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, University of Montr\u00e9al Hospital Center (CHUM), Montr\u00e9al, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benoit","family":"Panzini","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, University of Montr\u00e9al Hospital Center (CHUM), Montr\u00e9al, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon","family":"Bouchard","sequence":"additional","affiliation":[{"name":"University of Montr\u00e9al Hospital Research Center (CRCHUM), Montr\u00e9al, Quebec, Canada"},{"name":"Division of Gastroenterology, University of Montr\u00e9al Hospital Center (CHUM), Montr\u00e9al, Quebec, 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