{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T14:26:47Z","timestamp":1740148007594,"version":"3.37.3"},"reference-count":30,"publisher":"Georg Thieme Verlag KG","issue":"01","funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"crossref","award":["NRF-2020R1G1A1102033"],"award-info":[{"award-number":["NRF-2020R1G1A1102033"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100002560","name":"Soonchunhyang University","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100002560","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nuklearmedizin"],"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Purpose We investigated the diagnostic performance of single photon emission computed tomography (SPECT)\/computed tomography (CT) as a combination of functional and anatomic imaging, in patients with unspecified chest wall pain.<\/jats:p><jats:p>\n          Methods Fifty-two patients with unspecified chest wall pain and no history of recent major traumatic events or cardiac disease were included. The number and location of radioactive chest wall lesions were evaluated on both planar images and SPECT\/CT. The clinical diagnosis was made based on all of the clinical and imaging data and follow-up information.<\/jats:p><jats:p>\n          Results Chest wall diseases were diagnosed in 42 patients (80.8 %). SPECT\/CT showed abnormal findings in 35 (67.3 %) patients with positive predictive value (PPV) of 97.1 %. SPECT\/CT revealed 56 % more lesions than planar bone scan (P = 0.002) and most of the abnormal radioactive lesions (94.6 %) showed combined morphological changes on the matched CT component. When comparing between age subgroups (&lt; 60 y vs. \u2265 60 y), the prevalence of chest wall disease and diagnosis rate of fracture was significantly higher in the older age group. On SPECT\/CT, the older age group showed higher frequency of having abnormal finding (95.8 % vs. 42.9 %, P &lt; 0.001) and significantly more lesions were detected (a total of 189 vs. 32, P = 0.003).<\/jats:p><jats:p>\n          Conclusion SPECT\/CT showed good diagnostic performance and proved to have higher sensitivity, detecting 56 % more lesions than planar bone scan. A negative result could be helpful for excluding pathologic chest wall disease. SPECT\/CT might be recommended for integration in to the diagnostic workup in patients with unspecified chest wall pain, especially in patients \u2265 60 y of age, considering the high disease prevalence and the high frequency of positive results.<\/jats:p>","DOI":"10.1055\/a-1549-5910","type":"journal-article","created":{"date-parts":[[2021,11,12]],"date-time":"2021-11-12T23:47:40Z","timestamp":1636760860000},"page":"16-24","source":"Crossref","is-referenced-by-count":2,"title":["Diagnostic Value of Bone SPECT\/CT Using 99mTc-Methylene Diphosphonate in Patients with Unspecified Chest Wall Pain"],"prefix":"10.1055","volume":"61","author":[{"given":"Soo Bin","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, Soonchunhyang University Hospital, Soonchunhyang University College of Medicine, Seoul, Korea (the Republic of)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chae Hong","family":"Lim","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, Soonchunhyang University Hospital, Soonchunhyang University College of Medicine, Seoul, Korea (the Republic of)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Won Ho","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery, Soonchunhyang University Hospital, Soonchunhyang University College of Medicine, Seoul, Korea (the Republic of)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jung Hwa","family":"Hwang","sequence":"additional","affiliation":[{"name":"Department of Radiology, Soonchunhyang University Hospital, Soonchunhyang University College of Medicine, Seoul, Korea (the Republic of)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ji Young","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, Jeju National University Hospital, Jeju National University School of Medicine, Jeju, Korea (the Republic of)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Young Hwan","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea (the Republic of)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jung Mi","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, Soonchunhyang University Bucheon Hospital, Soonchunhyang University College of Medicine, Bucheon, Korea (the Republic of)"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2021,11,12]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"863","DOI":"10.1016\/j.pop.2013.08.007","article-title":"Evaluation and treatment of musculoskeletal chest pain","volume":"40","author":"A Ayloo","year":"2013","journal-title":"Prim Care"},{"key":"ref2","first-page":"540","article-title":"Musculoskeletal chest wall pain","volume":"44","author":"T Winzenberg","year":"2015","journal-title":"Aust Fam Physician"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1186\/1471-2296-8-51","article-title":"Chest wall syndrome among primary care patients: a cohort study","volume":"8","author":"F Verdon","year":"2007","journal-title":"BMC Fam Pract"},{"key":"ref4","first-page":"345","article-title":"Episodes of care for chest pain: a preliminary report from MIRNET. 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