{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,14]],"date-time":"2026-03-14T01:07:40Z","timestamp":1773450460545,"version":"3.50.1"},"reference-count":33,"publisher":"Georg Thieme Verlag KG","issue":"12","license":[{"start":{"date-parts":[[2021,12,14]],"date-time":"2021-12-14T00:00:00Z","timestamp":1639440000000},"content-version":"vor","delay-in-days":13,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Endosc Int Open"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background and study aims\u2002Colon capsule endoscopy (CCE) has the potential to explore the entire gastrointestinal tract. The aim of this study was to assess the applicability of CCE as pan-endoscopy.<\/jats:p><jats:p>\n          Patients and methods\u2002Healthy participants received CCE with bowel preparation (bisacodyl, polyethylene electrolyte glycol (PEG)\u200a+\u200aascorbic acid) and booster regimen (metoclopramide, oral sulfate solution (OSS)). For each segment of the gastrointestinal tract, the following quality parameters were assessed: cleanliness, transit times, reading times, patient acceptance and safety of the procedure. When all gastrointestinal segments had cleansing score good or excellent, cleanliness of the whole gastrointestinal tract was assessed as good. Participants\u2019 expected and perceived burden was assessed by questionnaires and participants were asked to grade the procedure (scale 0\u201310). All serious adverse events (SAEs) were documented.<\/jats:p><jats:p>\n          Results\u2002A total of 451 CCE procedures were analyzed. A good cleansing score was achieved in the stomach in 69.6%, in the SB in 99.1\u200a% and in the colon in 76.6\u200a%. Cleanliness of the whole gastrointestinal tract was good in 52.8\u200a% of the participants. CCE median transit time of the whole gastrointestinal tract was 583 minutes IQR 303\u2013659). The capsule reached the descending colon in 94.7\u200a%. Median reading time per procedure was 70 minutes (IQR 57\u201383). Participants graded the procedure with a 7.8.\u200aThere were no procedure-related SAEs.<\/jats:p><jats:p>\n          Conclusions\u2002CCE as pan-endoscopy has shown to be a safe procedure with good patient acceptance. When cleanliness of all gastrointestinal segments per patient, completion rate and reading time will be improved, CCE can be applied as a good non-invasive alternative to evaluate the gastrointestinal tract.<\/jats:p>","DOI":"10.1055\/a-1578-1800","type":"journal-article","created":{"date-parts":[[2021,12,14]],"date-time":"2021-12-14T23:42:03Z","timestamp":1639525323000},"page":"E1852-E1859","source":"Crossref","is-referenced-by-count":18,"title":["Applicability of colon capsule endoscopy as pan-endoscopy: From bowel preparation, transit, and rating times to completion rate and patient acceptance"],"prefix":"10.1055","volume":"09","author":[{"given":"Fanny E.R.","family":"Vuik","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center, Rotterdam, the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah","family":"Moen","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center, Rotterdam, the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stella A.V.","family":"Nieuwenburg","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center, Rotterdam, the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eline H.","family":"Schreuders","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center, Rotterdam, the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ernst J.","family":"Kuipers","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center, Rotterdam, the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manon C.W.","family":"Spaander","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center, Rotterdam, the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2021,12,14]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1007\/s11894-018-0628-7","article-title":"Applications of colon capsule endoscopy","volume":"20","author":"S F Pasha","year":"2018","journal-title":"Curr Gastroenterol Rep"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.1016\/j.cgh.2016.04.038","article-title":"Accuracy of First- and second-generation colon capsules in endoscopic detection of colorectal polyps: a systematic review and meta-analysis","volume":"14","author":"C Spada","year":"2016","journal-title":"Clin Gastroenterol Hepatol"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1055\/a-1249-3938","article-title":"Diagnostic accuracy of capsule endoscopy compared with colonoscopy for polyp detection: systematic review and meta-analyses","volume":"53","author":"T Kj\u00f8lhede","year":"2021","journal-title":"Endoscopy"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"3367","DOI":"10.3390\/cancers12113367","article-title":"Colon capsule endoscopy vs. ct colonography following incomplete colonoscopy: a systematic review with meta-analysis","volume":"12","author":"U Deding","year":"2020","journal-title":"Cancers (Basel)"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1055\/a-1258-4819","article-title":"Imaging alternatives to colonoscopy: CT colonography and colon capsule. 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