{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T08:33:41Z","timestamp":1740126821623,"version":"3.37.3"},"reference-count":17,"publisher":"Georg Thieme Verlag KG","issue":"13","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Perinatol"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:p>\n            Objective\u2003This study aimed to identify extremely premature infants (&lt; 31 weeks of gestation and\/or &lt;1,500\u2009g) affected by congenital hypothyroidism (CH) with delayed elevation of thyrotropin (TSH) and to evaluate the detection strategy for this pathology in our reference screening population.<\/jats:p><jats:p>\n            Study Design\u2003A descriptive and retrospective study was carried out with samples collected from western Andalusia and the autonomous city of Ceuta.<\/jats:p><jats:p>\n            Results\u2003This protocol allowed us to detect six neonates with delayed TSH elevation. One of them, due to serious heart problems, died without being able to confirm CH. In two neonates, however, it was possible to detect CH, another two presented a persistent TSH elevation but normal free T4, and another one presented a temporary TSH elevation.<\/jats:p><jats:p>\n            Conclusion\u2003It is essential to repeat the CH screening in extremely premature infants, not only at the age of 15 days but also with a third sample at the moment of hospital discharge to detect cases with delayed TSH elevation.<\/jats:p><jats:p>\n            Key Points\n          <\/jats:p>","DOI":"10.1055\/a-1627-0240","type":"journal-article","created":{"date-parts":[[2021,8,31]],"date-time":"2021-08-31T22:43:35Z","timestamp":1630449815000},"page":"1421-1424","source":"Crossref","is-referenced-by-count":0,"title":["Evaluation of the Congenital Hypothyroidism Detection Strategy in Extremely Preterm Infants in Western Andalusia"],"prefix":"10.1055","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6313-4191","authenticated-orcid":false,"given":"Ricardo","family":"Rubio-S\u00e1nchez","sequence":"additional","affiliation":[{"name":"Department of Clinical Biochemistry, Virgen de Valme University Hospital, Seville, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"N\u00fa\u00f1ez-Jurado","sequence":"additional","affiliation":[{"name":"Department of Clinical Biochemistry, Virgen del Roc\u00edo University Hospital, Seville, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enrique","family":"Melguizo-Madrid","sequence":"additional","affiliation":[{"name":"Department of Clinical Biochemistry, Virgen del Roc\u00edo University Hospital, Seville, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana I.","family":"\u00c1lvarez-R\u00edos","sequence":"additional","affiliation":[{"name":"Department of Clinical Biochemistry, Virgen del Roc\u00edo University Hospital, Seville, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carmen","family":"Delgado-Pecell\u00edn","sequence":"additional","affiliation":[{"name":"Department of Clinical Biochemistry, Virgen del Roc\u00edo University Hospital, Seville, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2021,9,24]]},"reference":[{"issue":"04","key":"ref1","first-page":"205","article-title":"[Fifty years of neonatal screening for congenital diseases in Spain]","volume":"90","author":"M L Couce","year":"2019","journal-title":"An Pediatr (Engl Ed)"},{"issue":"04","key":"ref2","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1136\/adc.2010.190280","article-title":"Prevention of intellectual disability through screening for congenital hypothyroidism: how much and at what level?","volume":"96","author":"S D Grosse","year":"2011","journal-title":"Arch Dis Child"},{"volume-title":"Programas de cribado neonatal en Espa\u00f1a: Actualizaci\u00f3n y propuestas de futuro","year":"2009","author":"J L Mar\u00edn","key":"ref3"},{"issue":"02","key":"ref4","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1210\/jc.2013-1891","article-title":"European Society for Paediatric Endocrinology consensus guidelines on screening, diagnosis, and management of congenital hypothyroidism","volume":"99","author":"J L\u00e9ger","year":"2014","journal-title":"J Clin Endocrinol Metab"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/s13633-017-0051-0","article-title":"Congenital hypothyroidism: insights into pathogenesis and treatment","volume":"2017","author":"C E Cherella","year":"2017","journal-title":"Int J Pediatr Endocrinol"},{"volume-title":"Programa de cribado neonatal de enfermedades endocrino-metab\u00f3licas de Andaluc\u00eda","year":"2016","author":"R Camino","key":"ref6"},{"issue":"06","key":"ref7","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1016\/j.jpeds.2014.02.031","article-title":"Screening preterm infants for congenital hypothyroidism: better the second time around","volume":"164","author":"S H LaFranchi","year":"2014","journal-title":"J Pediatr"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/j.jpeds.2018.11.044","article-title":"Increased congenital hypothyroidism detection in preterm infants with serial newborn screening","volume":"207","author":"D C Kaluarachchi","year":"2019","journal-title":"J Pediatr"},{"issue":"01","key":"ref9","doi-asserted-by":"crossref","first-page":"15","DOI":"10.6065\/apem.2019.24.1.15","article-title":"Screening and management of thyroid dysfunction in preterm infants","volume":"24","author":"H R Chung","year":"2019","journal-title":"Ann Pediatr Endocrinol Metab"},{"issue":"20","key":"ref10","doi-asserted-by":"crossref","first-page":"2191","DOI":"10.1001\/jama.2013.281053","article-title":"World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects","volume":"310","author":"World Medical Association","year":"2013","journal-title":"JAMA"},{"issue":"07","key":"ref11","doi-asserted-by":"crossref","first-page":"3209","DOI":"10.1210\/jcem.87.7.8662","article-title":"Subclinical hypothyroidism in early childhood: a frequent outcome of transient neonatal hyperthyrotropinemia","volume":"87","author":"F Calaciura","year":"2002","journal-title":"J Clin Endocrinol Metab"},{"key":"ref12","first-page":"1","article-title":"Resultados del cribado neonatal de Andaluc\u00eda Occidental tras una d\u00e9cada de experiencia","volume":"94","author":"C Delgado-Pecell\u00edn","year":"2020","journal-title":"Rev Esp Salud P\u00fablica"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.jpeds.2018.09.044","article-title":"Optimal timing of repeat newborn screening for congenital hypothyroidism in preterm infants to detect delayed thyroid-stimulating hormone elevation","volume":"205","author":"N McGrath","year":"2019","journal-title":"J Pediatr"},{"issue":"04","key":"ref14","doi-asserted-by":"crossref","first-page":"F286","DOI":"10.1136\/adc.2007.134999","article-title":"Repeat testing for congenital hypothyroidism in preterm infants is unnecessary with an appropriate thyroid stimulating hormone threshold","volume":"93","author":"M Korada","year":"2008","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"issue":"03","key":"ref15","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1067\/mpd.2002.120268","article-title":"Very low birth weight newborns do not need repeat screening for congenital hypothyroidism","volume":"140","author":"M A Vincent","year":"2002","journal-title":"J Pediatr"},{"issue":"01","key":"ref16","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.pedneo.2017.04.006","article-title":"Screening of congenital hypothyroidism in preterm, low birth weight and very low birth weight neonates: a systematic review","volume":"59","author":"M Hashemipour","year":"2018","journal-title":"Pediatr Neonatol"},{"issue":"05","key":"ref17","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1530\/EJE-15-1233","article-title":"Congenital hypothyroidism with delayed TSH elevation in low-birth-weight infants: incidence, diagnosis and management","volume":"175","author":"P Cavarzere","year":"2016","journal-title":"Eur J Endocrinol"}],"container-title":["American Journal of Perinatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-1627-0240.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,18]],"date-time":"2023-09-18T23:12:49Z","timestamp":1695078769000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-1627-0240"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,8,31]]},"references-count":17,"journal-issue":{"issue":"13","published-online":{"date-parts":[[2023,9,18]]},"published-print":{"date-parts":[[2023,10]]}},"URL":"https:\/\/doi.org\/10.1055\/a-1627-0240","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0735-1631","1098-8785"],"issn-type":[{"type":"print","value":"0735-1631"},{"type":"electronic","value":"1098-8785"}],"subject":[],"published-other":{"date-parts":[[2021,8,31]]},"published":{"date-parts":[[2021,8,31]]}}}