{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T08:33:44Z","timestamp":1740126824098,"version":"3.37.3"},"reference-count":24,"publisher":"Georg Thieme Verlag KG","issue":"12","funder":[{"name":"Bundesministerium f\u00fcr Bildung und Forschung\n                    gef\u00f6rdert","award":["01EO1004"],"award-info":[{"award-number":["01EO1004"]}]},{"name":"Bundesministerium f\u00fcr Bildung und Forschung\n                        gef\u00f6rdert","award":["01EO1504"],"award-info":[{"award-number":["01EO1504"]}]},{"name":"STAABCOVID\n                        Programm wird gef\u00f6rdert durch das Bayerische Staatsministerium\n                        f\u00fcr Wissenschaft und Kunst","award":["U.7-H4001.1.7\/24\/2"],"award-info":[{"award-number":["U.7-H4001.1.7\/24\/2"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gesundheitswesen"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>\n          Ziel der Studie Die aktuelle SARS-CoV-2 Forschung fokussiert sich bisher\n                    weitgehend auf symptomatische F\u00e4lle. Die STAAB-COVID-Studie untersuchte\n                    daher die Seropr\u00e4valenz von COVID-19 in der Allgemeinbev\u00f6lkerung\n                    und die psychosozialen Auswirkungen der Pandemie.<\/jats:p><jats:p>\n          Methodik Von Juni-Oktober 2020 wurden im Rahmen des STAAB-COVID-Programms,\n                    einer Unterstudie der \u201eH\u00e4ufigkeit und Einflussfaktoren auf\n                    fr\u00fche STAdien A und B der Herzinsuffizienz in der Bev\u00f6lkerung\n                    (STAAB)\u201c Kohortenstudie, 4860 Probanden aus einer\n                    repr\u00e4sentativen altersstratifizierten Stichprobe W\u00fcrzburger\n                    Einwohner zur Blutabnahme und Fragebogenerhebung eingeladen. Alle Teilnehmenden\n                    erhielten zudem das Angebot, an einer Punktpr\u00e4valenzerhebung\n                    (selbst-entnommener Nasenabstrich Anfang November 2020) teilzunehmen.<\/jats:p><jats:p>\n          Ergebnisse Insgesamt nahmen 3034 Probanden am STAAB-COVID-Programm teil\n                    (Antwortrate 62%). Bei 33 Teilnehmenden (1,1%; 95%\n                    Konfidenzintervall 0,7\u20131,5%) wurden Antik\u00f6rper gegen\n                    SARS-CoV-2 nachgewiesen. H\u00f6here Werte auf der GAD-7-Angstskala waren mit\n                    niedrigeren Raten von SARS-CoV-2-Antik\u00f6rpern assoziiert (Odds\n                    Ratio=0,78 je+1 Punkt im GAD-7; 95% Konfidenzintervall\n                    0,65\u20130,95). Innerhalb dieser eher \u00e4ngstlichen Probandengruppe\n                    war jedoch auch die Absagerate von medizinischen Terminen erh\u00f6ht (Odds\n                    Ratio=1,13 je+1 Punkt im GAD-7; 95% Konfidenzintervall\n                    1,10\u20131,16). Bei sechs von insgesamt 2451 Teilnehmenden der\n                    Punktpr\u00e4valenzerhebung (0,24%; 95% Konfidenzintervall\n                    0,09\u20130,53%) wurde eine akute Infektion nachgewiesen.<\/jats:p><jats:p>\n          Schlussfolgerung Zwischen der ersten und zweiten COVID-19 Welle fanden wir\n                    in W\u00fcrzburg eine geringe Durchseuchung mit SARS-CoV-2. Eine\n                    \u00e4ngstlichere Pers\u00f6nlichkeit war dabei mit einer geringeren\n                    Seropr\u00e4valenz assoziiert. Die Studiendurchf\u00fchrung wurde durch\n                    die bereits bestehende Kohortenstudie entscheidend erleichtert.<\/jats:p>","DOI":"10.1055\/a-1630-7601","type":"journal-article","created":{"date-parts":[[2021,10,13]],"date-time":"2021-10-13T03:31:28Z","timestamp":1634095888000},"page":"965-975","source":"Crossref","is-referenced-by-count":5,"title":["Seropr\u00e4valenz von COVID-19 und psychosoziale Auswirkungen in\n                    der Allgemeinbev\u00f6lkerung: Ergebnisse des STAAB-COVID-One\n                    Programms"],"prefix":"10.1055","volume":"83","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5415-0456","authenticated-orcid":false,"given":"Felizitas A","family":"Eichner","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Klinische Epidemiologie und Biometrie,\n                    Universit\u00e4t W\u00fcrzburg, W\u00fcrzburg,\n                    Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G\u00f6tz","family":"Gelbrich","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Klinische Epidemiologie und Biometrie,\n                    Universit\u00e4t W\u00fcrzburg, W\u00fcrzburg,\n                    Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benedikt","family":"Wei\u00dfbrich","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Virologie und Immunbiologie, Universit\u00e4t\n                    W\u00fcrzburg, Wurzburg, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lars","family":"D\u00f6lken","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Virologie und Immunbiologie, Universit\u00e4t\n                    W\u00fcrzburg, Wurzburg, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oliver","family":"Kurzai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00fcrgen","family":"Deckert","sequence":"additional","affiliation":[{"name":"Klinik und Poliklinik f\u00fcr Psychiatrie, Psychosomatik und\n                    Psychotherapie, Universit\u00e4tsklinikum W\u00fcrzburg, Wurzburg,\n                    Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georg","family":"Ertl","sequence":"additional","affiliation":[{"name":"Innere Medizin, Universit\u00e4tsklinikum W\u00fcrzburg,\n                    Wurzburg, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Barth","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Grit","family":"Hein","sequence":"additional","affiliation":[{"name":"Klinik und Poliklinik f\u00fcr 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