{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T16:49:44Z","timestamp":1781714984841,"version":"3.54.5"},"reference-count":36,"publisher":"Georg Thieme Verlag KG","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Z Gastroenterol"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Guidelines recommend vaccination against SARS-CoV-2 in transplant recipients, candidates, and their household contacts. However, little is known about the acceptance of COVID-19 vaccines in these groups.<\/jats:p><jats:p>In March 2021, we surveyed 826 liver transplant recipients, candidates, and their household contacts to determine acceptance rates and factors influencing the acceptance of the COVID-19 vaccine; 341 patients (40%) and 237 household contacts (28%) returned the questionnaire. Ninety percent of patients returning the survey reported they were willing to receive the vaccine within the next 6 months or had already started vaccination. Only 2% of patients and 4% of household contacts reported refusing the vaccine, and 8% of patients and 9% of household contacts wanted to postpone vaccination because of concerns about side effects. Having received the influenza vaccine in the last 2 seasons was the strongest indicator of acceptance to receive the SARS-CoV-2 vaccine within 6 months (odds ratio 5.11; 95% confidence interval 2.43\u201310.74; p &lt; 0.001). Thirty-two percent of responding patients reported fear of side effects as a reason for having refused vaccination before.<\/jats:p><jats:p>Although the acceptance of the SARS-CoV-2 vaccine was particularly high among German liver transplant recipients, candidates, and household contacts in this survey, transplant physicians are encouraged to discuss safety concerns with patients who have refused the seasonal influenza vaccine in the past.<\/jats:p>","DOI":"10.1055\/a-1649-8568","type":"journal-article","created":{"date-parts":[[2021,10,20]],"date-time":"2021-10-20T22:44:47Z","timestamp":1634769887000},"page":"1288-1296","source":"Crossref","is-referenced-by-count":4,"title":["Acceptance of SARS-CoV-2 vaccines by liver transplant recipients and candidates"],"prefix":"10.1055","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7696-475X","authenticated-orcid":false,"given":"Philipp A.","family":"Reuken","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Innere Medizin IV, Universit\u00e4tsklinikum Jena, Jena, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefanie","family":"Albers","sequence":"additional","affiliation":[{"name":"Medizinische Klinik III, Universit\u00e4tsklinikum Aachen (RWTH), Aachen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Falk","family":"Rauchfuss","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Allgemein-, Viszeral- und Gef\u00e4\u00dfchirurgie, Universit\u00e4tsklinikum Jena, Jena, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pavel","family":"Strnad","sequence":"additional","affiliation":[{"name":"Medizinische Klinik III, Universit\u00e4tsklinikum Aachen (RWTH), Aachen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Utz","family":"Settmacher","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Allgemein-, Viszeral- und Gef\u00e4\u00dfchirurgie, Universit\u00e4tsklinikum Jena, Jena, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Trautwein","sequence":"additional","affiliation":[{"name":"Medizinische Klinik III, Universit\u00e4tsklinikum Aachen (RWTH), Aachen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Stallmach","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Innere Medizin IV, Universit\u00e4tsklinikum Jena, Jena, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tony","family":"Bruns","sequence":"additional","affiliation":[{"name":"Medizinische Klinik III, Universit\u00e4tsklinikum Aachen (RWTH), Aachen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2021,10,20]]},"reference":[{"key":"ref2","doi-asserted-by":"publisher","first-page":"567","DOI":"10.1016\/j.jhep.2020.09.024","article-title":"Outcomes following SARS-CoV-2 infection in patients with chronic liver disease: an international registry study","volume":"74","author":"T Marjot","year":"2021","journal-title":"J Hepatol"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1002\/hep.31797","article-title":"Outcome of COVID-19 in patients with autoimmune hepatitis: an international multi-centre study","author":"C Efe","year":"2021","journal-title":"Hepatol Baltim Md"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"1008","DOI":"10.1016\/S2468-1253(20)30271-5","article-title":"Outcomes following SARS-CoV-2 infection in liver transplant recipients: an international registry study","volume":"5","author":"GJ Webb","year":"2020","journal-title":"Lancet Gastroenterol Hepatol"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.16118","article-title":"Between fear and courage: attitudes, beliefs, and behavior of liver transplantation recipients and waiting list candidates during the COVID-19 pandemic","author":"PA Reuken","year":"2020","journal-title":"Am J Transplant Off J Am Soc Transplant Am Soc Transpl Surg"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"944","DOI":"10.1016\/j.jhep.2021.01.032","article-title":"EASL position paper on the use of COVID-19 vaccines in patients with chronic liver diseases, hepatobiliary cancer and liver transplant recipients","volume":"74","author":"M Cornberg","year":"2021","journal-title":"J Hepatol"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1002\/hep.31751","article-title":"AASLD Expert Panel Consensus Statement: Vaccines to Prevent COVID-19 Infection in Patients with Liver Disease","author":"OK Fix","year":"2021","journal-title":"Hepatol Baltim Md"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"345","DOI":"10.1055\/a-1372-5595","article-title":"S1-Leitlinie zur Versorgung von Lebertransplantierten w\u00e4hrend der COVID-19-Pandemie \u2013 AWMF-Register Nr. 021\u2013031 \u2013 Stand: 07.01.21","volume":"59","author":"F Tacke","year":"2021","journal-title":"Z F\u00fcr Gastroenterol"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"977","DOI":"10.1007\/s10198-020-01208-6","article-title":"Once we have it, will we use it? A European survey on willingness to be vaccinated against COVID-19","volume":"21","author":"S Neumann-B\u00f6hme","year":"2020","journal-title":"Eur J Health Econ HEPAC Health Econ Prev Care"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1126\/science.372.6537.14","article-title":"Side effect worry grows for AstraZeneca vaccine","volume":"372","author":"G Vogel","year":"2021","journal-title":"Science"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(21)00155-8","article-title":"Short-term safety of the BNT162b2 mRNA COVID-19 vaccine in patients with cancer treated with immune checkpoint inhibitors","author":"B Waissengrin","year":"2021","journal-title":"Lancet Oncol"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"n883","DOI":"10.1136\/bmj.n883","article-title":"Covid-19: EMA defends AstraZeneca vaccine as Germany and Canada halt rollouts","author":"O Dyer","year":"2021","journal-title":"BMJ"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1038\/d41586-021-00785-7","article-title":"What scientists do and don\u2019t know about the Oxford-AstraZeneca COVID vaccine","volume":"592","author":"S Mallapaty","year":"2021","journal-title":"Nature"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2021.4385","article-title":"Immunogenicity of a single dose of SARS-CoV-2 messenger RNA vaccine in solid organ transplant recipients","author":"BJ Boyarsky","year":"2021","journal-title":"J Am Med Assoc"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2021.03.014","article-title":"Weak anti-SARS-CoV-2 antibody response after the first injection of an mRNA COVID-19 vaccine in kidney transplant recipients","author":"I Benotmane","year":"2021","journal-title":"Kidney Int"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2020-219811","article-title":"Potential acceptance of COVID-19 vaccine in rheumatological patients: a monocentric comparative survey","author":"C Campochiaro","year":"2021","journal-title":"Ann Rheum Dis"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines9040302","article-title":"COVID-19 vaccine hesitancy among French people living with HIV","volume":"9","author":"A Vall\u00e9e","year":"2021","journal-title":"Vaccines"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"102880","DOI":"10.1016\/j.msard.2021.102880","article-title":"Willingness to be vaccinated against COVID-19: an exploratory online survey in a Portuguese cohort of multiple sclerosis patients","volume":"51","author":"F Serrazina","year":"2021","journal-title":"Mult Scler Relat Disord"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1007\/s00296-021-04841-3","article-title":"Willingness to get the COVID-19 vaccine among patients with rheumatic diseases, healthcare workers and general population in Turkey: a web-based survey","author":"B Yurttas","year":"2021","journal-title":"Rheumatol Int"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1016\/j.annonc.2021.01.066","article-title":"Acceptance of SARS-CoV-2 vaccination among French patients with cancer: a cross-sectional survey","author":"J Barri\u00e8re","year":"2021","journal-title":"Ann Oncol Off J Eur Soc Med Oncol"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.3390\/healthcare9030351","article-title":"Vaccine Enthusiasm and hesitancy in cancer patients and the impact of a webinar","volume":"9","author":"AH Kelkar","year":"2021","journal-title":"Healthc Basel Switz"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2021.02.005","article-title":"International estimates of intended uptake and refusal of COVID-19 vaccines: a rapid systematic review and meta-analysis of large nationally representative samples","author":"E Robinson","year":"2021","journal-title":"Vaccine"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1186\/s41256-021-00188-1","article-title":"Willingness of Greek general population to get a COVID-19 vaccine","volume":"6","author":"G Kourlaba","year":"2021","journal-title":"Glob Health Res Policy"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"100495","DOI":"10.1016\/j.eclinm.2020.100495","article-title":"Determinants of COVID-19 vaccine acceptance in the US","volume":"26","author":"AA Malik","year":"2020","journal-title":"EClinicalMedicine"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1007\/s00103-019-03063-0","article-title":"Understanding vaccine acceptance and demand-and ways to increase them","volume":"63","author":"KB Habersaat","year":"2020","journal-title":"Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1038\/s41467-020-20226-9","article-title":"Psychological characteristics associated with COVID-19 vaccine hesitancy and resistance in Ireland and the United Kingdom","volume":"12","author":"J Murphy","year":"2021","journal-title":"Nat Commun"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"799","DOI":"10.1080\/10810730.2020.1868630","article-title":"Hesitant or not? The association of age, gender, and education with potential acceptance of a COVID-19 vaccine: a country-level analysis","volume":"25","author":"JV Lazarus","year":"2020","journal-title":"J Health Commun"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1007\/s10900-021-00987-0","article-title":"Factors associated with willingness to be vaccinated against COVID-19 in a large convenience sample","author":"C Dorman","year":"2021","journal-title":"J Community Health"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"2276","DOI":"10.18549\/PharmPract.2021.1.2276","article-title":"Determinants of COVID-19 vaccine acceptance in a high infection-rate country: a cross-sectional study in Russia","volume":"19","author":"VD Tran","year":"2021","journal-title":"Pharm Pract"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines9030210","article-title":"Acceptance of a COVID-19 vaccine in Japan during the COVID-19 pandemic","volume":"9","author":"M Machida","year":"2021","journal-title":"Vaccines"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1080\/21645515.2021.1899732","article-title":"Factors associated with the willingness and acceptance of SARS-CoV-2 vaccine from adult subjects in China","author":"D Liu","year":"2021","journal-title":"Hum Vaccines Immunother"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10071388","article-title":"Acceptance and intake of COVID-19 vaccines among older Germans","volume":"10","author":"M Malesza","year":"2021","journal-title":"J Clin Med"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"2317","DOI":"10.18549\/PharmPract.2021.1.2317","article-title":"Attitudes towards COVID-19 vaccination, vaccine hesitancy and intention to take the vaccine","volume":"19","author":"M Cordina","year":"2021","journal-title":"Pharm Pract"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph18041993","article-title":"Willingness to receive SARS-CoV-2 vaccination and associated factors among Chinese adults: a cross sectional survey","volume":"18","author":"L Gan","year":"2021","journal-title":"Int J Environ Res Public Health"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1016\/j.jpeds.2020.08.005","article-title":"Willingness to vaccinate children against influenza after the coronavirus disease 2019 Pandemic","volume":"228","author":"RD Goldman","year":"2021","journal-title":"J Pediatr"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines8040711","article-title":"Attitudes and beliefs on influenza vaccination during the COVID-19 Pandemic: results from a representative Italian survey","volume":"8","author":"A Domnich","year":"2020","journal-title":"Vaccines"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"844","DOI":"10.1016\/j.healun.2018.03.001","article-title":"Does vaccination in solid-organ transplant recipients result in adverse immunologic sequelae? A systematic review and meta-analysis","volume":"37","author":"WR Mulley","year":"2018","journal-title":"J Heart Lung Transplant Off Publ Int Soc Heart Transplant"}],"container-title":["Zeitschrift f\u00fcr Gastroenterologie"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-1649-8568.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,11]],"date-time":"2021-12-11T00:32:59Z","timestamp":1639182779000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-1649-8568"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10,20]]},"references-count":36,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2021,12,10]]},"published-print":{"date-parts":[[2021,12]]}},"URL":"https:\/\/doi.org\/10.1055\/a-1649-8568","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0044-2771","1439-7803"],"issn-type":[{"value":"0044-2771","type":"print"},{"value":"1439-7803","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,10,20]]}}}