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An 18F-FDG PET\/CT revealed an overall low metabolic activity of the lesions with a diffuse bone marrow involvement raising suspicion of a haematological neoplasm. Subsequently, bone marrow and peripheral blood examinations confirmed the diagnosis of aggressive systemic mastocytosis.<\/jats:p>","DOI":"10.1055\/a-1650-9704","type":"journal-article","created":{"date-parts":[[2021,10,29]],"date-time":"2021-10-29T23:30:15Z","timestamp":1635550215000},"page":"58-61","source":"Crossref","is-referenced-by-count":3,"title":["Aggressive systemic mastocytosis with diffuse bone marrow 18F-FDG uptake"],"prefix":"10.1055","volume":"61","author":[{"given":"Renata","family":"Koukalov\u00e1","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, PET centre, Masaryk Memorial Cancer Institute, Brno, Czech Republic"},{"name":"Faculty of Medicine, Masaryk University, Brno, Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ji\u0159\u00ed","family":"Va\u0161ina","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, PET centre, Masaryk Memorial Cancer Institute, Brno, Czech Republic"},{"name":"Faculty of Medicine, Masaryk University, Brno, Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ji\u0159\u00ed","family":"\u0160tika","sequence":"additional","affiliation":[{"name":"Central European Institute of Technology (CEITEC), Brno, Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Doubek","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Haematology and Oncology, University Hospital Brno, Brno, Czech Republic"},{"name":"Faculty of Medicine, Masaryk University, Brno, Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Petr","family":"Szturz","sequence":"additional","affiliation":[{"name":"Department of Oncology, University of Lausanne (UNIL) and Lausanne University Hospital (CHUV), Lausanne, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2021,10,29]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"508","DOI":"10.1002\/ajh.26118","article-title":"Systemic mastocytosis in adults: 2021 Update on diagnosis, risk stratification and management","volume":"96","author":"A Pardanani","year":"2021","journal-title":"Am J Hematol"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1038\/nbt.1754","article-title":"Integrative genomics viewer","volume":"29","author":"JT Robinson","year":"2011","journal-title":"Nat Biotechnol"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"1235","DOI":"10.2214\/ajr.179.5.1791235","article-title":"FDG positron emission tomography in patients with systemic mastocytosis","volume":"179","author":"G Zettinig","year":"2002","journal-title":"AJR Am J Roentgenol"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"220","DOI":"10.1097\/RLU.0b013e3181638e5e","article-title":"Imaging of systemic mastocytosis by FDG-PET\/CT demonstrates increased activity in cortical bone","volume":"33","author":"RT Tomihama","year":"2008","journal-title":"Clin Nucl Med"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"2013","DOI":"10.1007\/s00259-015-3117-3","article-title":"FDG-PET\/CT findings in systemic mastocytosis: a French multicentre study","volume":"42","author":"S Djelbani-Ahmed","year":"2015","journal-title":"Eur J Nucl Med Mol Imaging"}],"container-title":["Nuklearmedizin - NuclearMedicine"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-1650-9704.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,6,30]],"date-time":"2022-06-30T06:06:59Z","timestamp":1656569219000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-1650-9704"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10,29]]},"references-count":5,"journal-issue":{"issue":"01","published-online":{"date-parts":[[2022,2,4]]},"published-print":{"date-parts":[[2022,2]]}},"URL":"https:\/\/doi.org\/10.1055\/a-1650-9704","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0029-5566","2567-6407"],"issn-type":[{"value":"0029-5566","type":"print"},{"value":"2567-6407","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,10,29]]}}}