{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T13:49:24Z","timestamp":1784036964818,"version":"3.55.0"},"reference-count":74,"publisher":"Georg Thieme Verlag KG","issue":"01","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Planta Med"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Potentilla alba is a valuable medicinal plant that has been highly praised even before its first appearance in herbal books; however, it has now been forgotten in Western Europe. Currently, this species is used in Eastern Europe as a remedy to treat dysentery and various thyroid gland dysfunctions. The present review summarizes the advances in the phytochemical, pharmacological, and toxicological research related to this plant species. Clinical trials that have been conducted to date support its traditional use for treating thyroid disorders, although its exact mechanism of action, bioavailability, and pharmacokinetics data are missing.<\/jats:p>","DOI":"10.1055\/a-1663-6461","type":"journal-article","created":{"date-parts":[[2021,10,29]],"date-time":"2021-10-29T23:20:50Z","timestamp":1635549650000},"page":"19-29","source":"Crossref","is-referenced-by-count":6,"title":["New Perspectives for the Use of Potentilla alba Rhizomes to Treat Thyroid Gland Impairments"],"prefix":"10.1055","volume":"89","author":[{"given":"Daniel","family":"Augustynowicz","sequence":"additional","affiliation":[{"name":"Department of Pharmacognosy, Faculty of Pharmacy with the Division of Laboratory Medicine, Medical University of Bia\u0142ystok, Bia\u0142ystok, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magdalena","family":"Podolak","sequence":"additional","affiliation":[{"name":"Student\u02bcs Scientific Association, Department of Pharmacognosy, Medical University of Bia\u0142ystok, Bia\u0142ystok, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Klaus Peter","family":"Latt\u00e9","sequence":"additional","affiliation":[{"name":"War\u00e4gerweg 21, Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Micha\u0142","family":"Tomczyk","sequence":"additional","affiliation":[{"name":"Department of Pharmacognosy, Faculty of Pharmacy with the Division of Laboratory Medicine, Medical University of Bia\u0142ystok, Bia\u0142ystok, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2021,10,29]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"1534","DOI":"10.1136\/bmj.319.7224.1534","article-title":"Hypericum extract versus imipramine or placebo in patients with moderate depression: randomised multicentre study of treatment for eight weeks","volume":"319","author":"M Philipp","year":"1999","journal-title":"BMJ"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"2935","DOI":"10.2174\/138161210793176464","article-title":"The efficacy and safety of herbal medicines used in the treatment of hyperlipidemia; a systematic review","volume":"16","author":"S Hasani-Ranjbar","year":"2010","journal-title":"Curr Pharm Des"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/j.bjp.2014.03.006","article-title":"Traditional use and safety of herbal medicines","volume":"24","author":"D L Moreira","year":"2014","journal-title":"Rev Bras Farmacogn"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1080\/10408398.2010.512426","article-title":"Herbs-are they safe enough? an overview","volume":"52","author":"D Singh","year":"2012","journal-title":"Crit Rev Food Sci Nutr"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"113412","DOI":"10.1016\/j.jep.2020.113412","article-title":"Recent phytochemical and pharmacological advances in the genus Potentilla L. sensu lato \u2013 An update covering the period from 2009 to 2020","volume":"266","author":"D Augustynowicz","year":"2021","journal-title":"J Ethnopharmacol"},{"key":"ref6","first-page":"58","article-title":"Thyrotoxicosis syndrome: new clinical opportunities for the correction of thyroid dysfunction","volume":"16","author":"V I Pankiv","year":"2020","journal-title":"Internat J Endocrinol"},{"key":"ref7","first-page":"9","article-title":"Technological aspects of the development of the tablet dry extract Potentilla alba L","volume":"21","author":"O A Semkina","year":"2018","journal-title":"Probl Biol Med Pharm Chem"},{"key":"ref8","volume-title":"Spedies Plantarum","author":"C Linn\u00e9","year":"1753"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/j.jep.2008.12.022","article-title":"Potentilla \u2013 a review of its phytochemical and pharmacological profile","volume":"122","author":"M Tomczyk","year":"2009","journal-title":"J Ethnopharmacol"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"297","DOI":"10.15835\/nbha3915452","article-title":"On the occurence in Romania of Potentillo albae-Quercetum petraeae Libbert 1933 association","volume":"39","author":"A Indreica","year":"2011","journal-title":"Not Bot Hort Agrobot Cluj"},{"key":"ref12","volume-title":"Rote Liste gef\u00e4hrdeter Tiere, Pflanzen und Pilze Deutschlands. 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Naturschutz und Biologische Vielfalt","author":"D Metzing","year":"2018"},{"key":"ref13","first-page":"58","article-title":"White cinquefoil, an effective agent for treating thyroid gland diseases","volume":"2","author":"G K Smyk","year":"1975","journal-title":"Farm Zh (Kiev)"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"1637","DOI":"10.1007\/s10722-018-0640-7","article-title":"Molecular cytogenetic characterization, leaf anatomy and ultrastructure of the medicinal plant Potentilla alba L","volume":"65","author":"T E Samatadze","year":"2018","journal-title":"Genet Resour Crop Evol"},{"key":"ref15","first-page":"28","article-title":"Pharmacognostic study of the rhizomes and the roots Potentilla alba L","volume":"1","author":"N G Bogacheva","year":"2016","journal-title":"Prob Biol Med Pharm Chem"},{"key":"ref16","volume-title":"New Kre\u00fcterbuch","author":"L Fuchs","year":"1543"},{"key":"ref17","volume-title":"Neu vollkommen Kr\u00e4uter-Buch: Darinnen \u00fcber 3000. 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Matkowski","year":"2006","journal-title":"Herba Pol"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"3080","DOI":"10.3390\/molecules25133080","article-title":"Potentilla alba extracts affect the viability and proliferation of non-cancerous and cancerous colon human epithelial cells","volume":"25","author":"K Kowalik","year":"2020","journal-title":"Molecules"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1134\/S1068162017070032","article-title":"Isolation and analysis of extractives from white cinquefoil (Potentilla alba L.) grown under different conditions","volume":"43","author":"N G Bazarnova","year":"2017","journal-title":"Russ J Bioorganic Chem"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1111\/j.1095-8339.1961.tb01079.x","article-title":"Chromatography and taxonomy in the Rosaceae with the special reference to Potentilla and Prunus","volume":"58","author":"E C Bate-Smith","year":"1961","journal-title":"Bot J Linn 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