{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T22:19:48Z","timestamp":1776723588639,"version":"3.51.2"},"reference-count":31,"publisher":"Georg Thieme Verlag KG","issue":"04","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pneumologie"],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Einleitung\u2002Die n\u00e4chtliche kontinuierliche positive \u00dcberdruckatmung (CPAP) gilt als therapeutischer Goldstandard einer obstruktiven Schlafapnoe (OSA). Die CPAP-Therapie stellt zumeist eine Dauertherapie mit geringen Nebenwirkungen dar. Trotzdem ist die Therapietreue unbefriedigend. In dieser Arbeit wurden die Therapietreue betrachtet und typische Probleme katalogisiert.<\/jats:p><jats:p>Methode\u20021078 OSA-Patienten wurden nach diagnostischer Polygrafie (PG) oder Polysomnografie (PSG) auf eine CPAP-Therapie eingestellt. Die Therapietreue wurde nach 3 Monaten nachverfolgt. Folgende Therapieadh\u00e4renz-Gruppen wurden festgelegt: 1. gute CPAP-Einstellung und Nutzung, 2. CPAP-Abbruch nach anf\u00e4nglicher Nutzung, 3. mangelnde CPAP-Nutzung wegen Nebenwirkungen, 4. Abbruch aufgrund fehlender Motivation\/geringem Leidensdruck, 5. Masken-Unvertr\u00e4glichkeit, 6. CPAP-Versagen aufgrund fehlenden Therapieeffekts, 7. Umstellung auf anderes Beatmungsverfahren, 8. keine Kontrolle erfolgt.<\/jats:p><jats:p>Ergebnisse\u2002Von 1078 CPAP-Patienten erschienen 830 Patienten (77\u200a%) zur Therapiekontrolle. Hiervon waren 450 Patienten (54,2\u200a%) in Gruppe 1, 216 Patienten (26\u200a%) in Gruppe 2, 71 Patienten (8,5\u200a%) in Gruppe 3, 35 Patienten (4,2\u200a%) in Gruppe 4, 14 Patienten (1,7\u200a%) in Gruppe 5, 3 Patienten (0,4\u200a%) in Gruppe 6 und 41 Patienten (4,9\u200a%) in Gruppe 7. Ein geringer obstruktiver Ereignisindex, niedriger CPAP-Druck und tendenziell auch ein geringer Epworth-Sleepiness-Score waren Pr\u00e4diktoren f\u00fcr CPAP-Versagen. F\u00fcr die Therapietreue konnten keine signifikanten Pr\u00e4diktoren dargestellt werden.<\/jats:p><jats:p>Diskussion\u2002Eine effektive Therapienutzung von 54\u200a% nach 3 Monaten ist ein suboptimales Ergebnis. Pr\u00e4diktoren f\u00fcr CPAP-Versagen waren Parameter, die vor Therapie auf geringen Leidensdruck der Patienten deuteten. Trotz gro\u00dfer Patientenkohorte konnten keine signifikanten CPAP-Adh\u00e4renz-Pr\u00e4diktoren durch anthropometrische oder PSG-Daten dargestellt werden. Vielmehr k\u00f6nnten Erfahrungen in den ersten Therapietagen ausschlaggebend sein. CPAP-Ger\u00e4te bieten Komforteinstellungen, die kenntnisgerecht auf den Patienten individualisiert werden m\u00fcssen. Eine gro\u00dfe Auswahl an unterschiedlichen Maskenformen erfordert Erfahrung und Training bei der patientenorientierten Maskenanpassung. Eine 3-monatige Wiedervorstellung erscheint zu lang, um Therapieprobleme zeitnah mit dem Patienten zu besprechen. Telemedizinische M\u00f6glichkeiten oder kurzfristige telefonische Beratungsoptionen sollten in Betracht gezogen werden.<\/jats:p>","DOI":"10.1055\/a-1666-5369","type":"journal-article","created":{"date-parts":[[2021,11,30]],"date-time":"2021-11-30T00:22:02Z","timestamp":1638231722000},"page":"251-259","source":"Crossref","is-referenced-by-count":6,"title":["Therapieadh\u00e4renz 3 Monate nach Einleitung einer nichtinvasiven CPAP-Therapie bei 1078 Patienten mit obstruktiver Schlafapnoe (OSA)"],"prefix":"10.1055","volume":"76","author":[{"given":"Julian","family":"Koehler","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Innere Medizin, SP Pneumologie, Intensiv- und Schlafmedizin, Philipps-Universit\u00e4t Marburg, Marburg"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olaf","family":"Hildebrandt","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Innere Medizin, SP Pneumologie, Intensiv- und Schlafmedizin, Philipps-Universit\u00e4t Marburg, Marburg"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Werner","family":"Cassel","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Innere Medizin, SP Pneumologie, Intensiv- und Schlafmedizin, Philipps-Universit\u00e4t Marburg, Marburg"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Regina","family":"Conradt","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Innere Medizin, SP Pneumologie, Intensiv- und Schlafmedizin, Philipps-Universit\u00e4t Marburg, Marburg"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Petra","family":"Mayr","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Innere Medizin, SP Pneumologie, Intensiv- und Schlafmedizin, Philipps-Universit\u00e4t Marburg, Marburg"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Alter","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Innere Medizin, SP Pneumologie, Intensiv- und Schlafmedizin, 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